Generation of mouse model of human cancer

人类癌症小鼠模型的产生

• 批准号: 7970048
• 负责人: Lino Tessarollo
• 金额: $ 29.07万
• 依托单位: DIVISION OF BASIC SCIENCES - NCI
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7970048
• 关键词: CCR; Disease; Ensure; Generations; Genes; Genetic; Genomics; Goals; Human; Human Pathology; Knowledge; Learning; Methods; Mus; Mutate; Patients; Research Personnel; Technical Expertise; Time; human cancer mouse model; human disease; improved; mouse genome; mouse model; sound; tool

We keep providing CCR investigators with the most recent and advanced technological knowledge on how to manipulate the mouse genome to best mimic human disease. This is a very difficult task because every year we learn more about the genetic component of disease in human and about the differences between the human and mouse. At the same time we are constantly improving our tools to facilitate the targeting of the mouse genome and we ensure that our methods are versatile and are economically sound.

我们不断为CCR研究人员提供最新和最先进的技术， 关于如何操纵小鼠基因组以最好地模拟人类疾病的知识。这是一个非常 这是一项艰巨的任务，因为每年我们都会更多地了解疾病的遗传成分， 人类以及人类和老鼠之间的区别。同时抱定 不断改进我们的工具，以促进小鼠基因组的靶向，我们确保 我们的方法是多功能的，而且经济合理。