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Regulation of Retinal Cell Death in Diabetes

Regulation of Retinal Cell Death in Diabetes
糖尿病视网膜细胞死亡的调节
批准号：
8197200
负责人：
Steven F Abcouwer
金额：
$44.57万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-05-01 至 2014-04-30
来源：
https://reporter.nih.gov/project-details/8197200
关键词：
AnimalsAnti-Inflammatory AgentsAnti-inflammatoryApoptoticBiochemicalBiological ModelsBlindnessBlood VesselsBrain DiseasesCell DeathCell SurvivalCellsCessation of lifeClinicalDataDiabetes MellitusDiabetic RetinopathyDiabetic mouseEquilibriumExhibitsEyeGlucoseGoalsGrowth FactorHealthHormonesHyperglycemiaIGF1 geneIGF2 geneImmuneInflammationInflammation MediatorsInflammatoryInsulinInsulin ReceptorInterdisciplinary StudyInterleukinsLasersLeadLightMediatingMetabolic stressMolecular GeneticsMusNerve DegenerationNervous system structureNeuronsOutcomePathway interactionsPersonsPharmaceutical PreparationsPhlorhizinPhosphotransferasesProductionProtein BiosynthesisProtein IsoformsProto-Oncogene Proteins c-aktRattusRegulationResearch PersonnelRetinaRetinalRetinal DegenerationRoleSignal PathwaySignal TransductionSignal Transduction PathwaySomatomedinsSystemSystemic infectionTNF geneTamoxifenTestingToxic effectVascular PermeabilitiesVisionVisual impairmentWithdrawalWorkabstractingangiogenesiscytokinediabetic ratimprovedinsightmouse modelneuron apoptosisneuronal survivalneurotoxicneurotoxicityneurotrophic factorneutralizing antibodynovelpreventreceptorrecombinaseresearch studyresponseretinal neurontool

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