Biodiversity surveys in Indonesia and discovery of health and energy solutions

印度尼西亚生物多样性调查以及健康和能源解决方案的发现

• 批准号: 7929567
• 负责人: Kyria Boundy-Mills
• 金额: $ 69.92万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-15 至 2013-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7929567
• 关键词: AIDS/HIV problem; Academy; Address; Agreement; Animals; Area; Arthropods; Bacteria; Biocompatible Materials; Biodiversity; Biological Factors; Biota; Birds; Cellulases; Charge; Collection; Complex; Data; Deposition; Development; Disease; Education and Outreach; Educational workshop; Ensure; Enzymes; Equipment and supply inventories; Ethics; Expeditions; Feedback; Forestry; Goals; Government Officials; Group Structure; Guidelines; Health; Human; Human Resources; Immune System Diseases; Indonesia; Industry; Insecta; Institutes; Institution; International; Invertebrates; Island; Knowledge; Lead; Lipids; Local Government; Malignant Neoplasms; Mammals; Metric; Microbe; Modeling; Molds; Multimedia; Museums; Natural Resources; Nature; Online Systems; Organism; Participant; Pattern; Pharmacologic Substance; Plant Leaves; Plant Roots; Plants; Policies; Principal Investigator; Process; Production; Property; Rain; Recommendation; Recording of previous events; Research; Resources; Sampling; San Francisco; Schedule; Science; Scientist; Screening procedure; Secure; Series; Shipping; Ships; Site; Soil; Solutions; Southeastern Asia; Specimen; Structure; Sulawesi; Surveys; Technology; Technology Transfer; Telecommunications; Therapeutic; Therapeutic Agents; Time; Training; Transcription Factor AP-1; United Nations; Universities; Vascular Plant; Vertebrates; Work; Yeasts; addiction; base; benefit sharing; cancer therapy; cellulase; data sharing; design; experience; forest; fungus; improved; knowledge base; material transfer agreement; meetings; microbial; novel; novel therapeutics; plant fungi; preclinical study; product development; programs; sound

DESCRIPTION (provided by applicant): The simultaneous study, conservation, and sustainable use of natural resources in tropical biodiversity hotspots require collaborative research partnerships of unprecedented scope and complexity, and the alarming rate at which biodiversity is being lost in many tropical regions has resulted in an urgent need for such efforts. We have assembled a multi-disciplinary, multi-institutional, international team to address the following objectives: 1) undertake surveys of biodiversity present in select taxonomic groups within the tropical forests of southeastern Sulawesi, a poorly studied yet threatened area of high species endemism within the biodiversity hotspot Wallacea; 2) explore the application of micro- and macro-organisms for natural product development for specific human health and bioenergy issues; 3) use the information from biodiversity surveys to develop recommendations for strategies to conserve endangered biomes and associated traditional and scientific knowledge bases; 4) develop and encourage local conservation planning, education, and outreach efforts that are ecologically, economically, and socio-politically sound; and 5) develop strong, equitable partnerships with effective international agreements relating to technology transfer, materials access, and benefit sharing. The project is organized into six Associate Programs: Macroorganism surveys; Microbial surveys; Discovery of energy solutions; Discovery of human health solutions; Conservation research and vertebrate surveys; and Conservation partnerships, training, and ethics. Our team includes scientists from three US Universities: UC Davis (lead), UC Berkeley, and UC San Francisco, and three prominent Indonesian institutions: Indonesian Institute of Science (lead agency), Indonesian Ministry of Forestry, and Bandung Institute of Technology. We will also form partnerships with private companies aimed at the commercial development of natural products for Pharmaceuticals and energy production, and we have secured collaborators from several other leading research institutions (e.g., Bishop Museum). An Indonesian-based Steering Committee, an International Advisory Board, and a web-based telecommunications and data-sharing network will provide critical guidance and interactive feedback loops for all participants throughout the course of the project. The results of this project will make significant contributions to a broad range of issues, including knowledge of patterns of biodiversity in southeast Asia, identification and isolation of natural products with potential therapeutic value to treat globally important diseases and to address human energy needs, development of effective biodiversity conservation strategies and proactive outreach and education programs to promote those strategies, and establishment of models for effective and equitable international collaborative partnerships and ethical and sustainable international sharing of biogenetic resources.

热带生物多样性热点地区自然资源的同步研究、保护和可持续利用需要前所未有的范围和复杂性的合作研究伙伴关系，许多热带地区生物多样性正在以惊人的速度丧失，因此迫切需要这种努力。我们组建了一个多学科、多机构的国际团队，以实现以下目标：1）对苏拉威西岛东南部热带森林中的选定分类群进行生物多样性调查，这是一个研究不足但受到威胁的地区，在生物多样性热点Wallacea内具有高度的物种特有性; 2）探索微生物和宏观生物体在天然产品开发中的应用，以解决特定的人类健康和生物能源问题; 3）利用生物多样性调查的信息，为保护濒危生物群落和相关的传统和科学知识基础的战略提出建议; 4）发展和鼓励当地的保护规划，教育和推广工作，是生态，经济和社会政治健全的; 5）与有关技术转让、材料获取和利益分享的有效国际协定建立强有力的、公平的伙伴关系。该项目分为六个副计划：大型生物调查;微生物调查;能源解决方案的发现;人类健康解决方案的发现;保护研究和脊椎动物调查;和保护伙伴关系，培训和道德。我们的团队包括来自三所美国大学的科学家：加州大学戴维斯分校（牵头），加州大学伯克利分校和加州大学旧金山分校弗朗西斯科，以及三个著名的印度尼西亚机构：印度尼西亚科学研究所（牵头机构），印度尼西亚林业部和万隆理工学院。我们还将与私营公司建立合作伙伴关系，旨在商业开发用于制药和能源生产的天然产品，我们已经从其他几个领先的研究机构（例如，主教博物馆）。一个设在埃塞俄比亚的指导委员会、一个国际咨询委员会以及一个网上电信和数据共享网络将在整个项目过程中为所有参与者提供重要指导和互动反馈回路。该项目的成果将对一系列广泛的问题作出重大贡献，包括了解东南亚的生物多样性模式，确定和分离具有潜在治疗价值的天然产品，以治疗全球重要疾病和满足人类能源需求，制定有效的生物多样性保护战略，以及积极的宣传和教育方案，以促进这些战略，并建立有效和公平的国际合作伙伴关系模式，在国际上以合乎道德和可持续的方式分享生物遗传资源。