Preventing Prematurity and Poor Pregnancy Outcomes Training Grant

预防早产和不良妊娠结局培训补助金

• 批准号: 8470673
• 负责人: John Jeffrey Reese
• 金额: $ 28.32万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-05-01 至 2016-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8470673
• 关键词: Grant; Pregnancy Outcome; Training; premature; prevent

DESCRIPTION (provided by applicant): This new T-32 application, "Preventing Prematurity and Poor Pregnancy Outcomes Training Grant", from the Division of Neonatology/Department of Pediatrics at Vanderbilt University School of Medicine is for the establishment of a postdoctoral training program for pediatric subspecialty fellows with a research and career focus in (a) developmental and perinatal biology, (b) genetic, environmental and biochemical/molecular causes of birth defects, preterm birth and its sequelae and (c) improvement in birth outcomes through translational, epidemiological, quality improvement and comparative effectiveness research. The long-term goals of this program are to develop physician-scientists and future leaders in perinatal research who will make career-long contributions that will positively impact birth outcomes. The Specific Aims are to identify promising trainees early in pediatric subspecialty fellowship training and provide them with a robust, interdisciplinary research experience under the supervision of a qualified mentor with ready access to adequate laboratory resources, populations or datasets of mothers and infants at risk of poor birth outcomes. This program will capitalize on the vast institutional resources at Vanderbilt including the Vanderbilt CTSA, a plethora of core facilities, the Masters in Public Health and Masters of Science in Clinical Investigation, the Quality Scholars Program and the Vanderbilt Evidence-based Practice Center. Given the strong applicant pool, we propose to fund two positions per year in each of the 2nd and 3rd years of fellowship training with commitment of institutional funds for continued training in a 4th year when desired. A talented group of NIH-funded investigators with proven track records of successful mentorship have been chosen from across multiple disciplines representing the unique research strengths of Vanderbilt University. The program's structured research training will instill the skills and knowledge required to address critical issues in perinatal health outcomes. Promising junior faculty have been identified as "mentors-in-training". A 4 member steering committee and a 6-member advisory committee of intramural and extramural experts in the fields of developmental biology, perinatal health outcomes and physician-scientist training will provide guidance on trainee selection and progress and overall program success.

描述(申请人提供)：这项新的T-32申请，“预防早产和不良妊娠结局培训补助金”，由新生/儿科范德比尔特大学医学院儿科，是为了建立一个面向儿科专科研究员的博士后培训计划，其研究和职业重点是：(A)发育和围产期生物学，(B)出生缺陷、早产及其后遗症的遗传、环境和生化/分子原因，以及(C)通过翻译、流行病学、质量改进和比较有效性研究来改善出生结果。该计划的长期目标是培养内科科学家和围产期研究的未来领导者，他们将做出职业生涯的贡献，对出生结果产生积极影响。具体目标是在儿科专科研究金培训早期确定有前途的受训者，并在合格导师的监督下为他们提供强大的跨学科研究经验，随时可以获得足够的实验室资源、人口或有不良出生结果风险的母亲和婴儿的数据集。该计划将利用范德比尔特的大量机构资源，包括范德比尔特CTSA、众多核心设施、公共卫生硕士和临床调查理学硕士、高质量学者计划和范德比尔特循证实践中心。鉴于申请者人数众多，我们建议在第二年和第三年的研究金培训中每年资助两个职位，并承诺在需要的情况下在第四年继续培训的机构资金。从代表范德比尔特大学独特研究优势的多个学科中挑选了一支由NIH资助的研究人员组成的才华横溢的团队，他们拥有成功的指导记录。该计划的结构化研究培训将灌输解决围产期健康结果关键问题所需的技能和知识。有前途的初级教员已被确定为“培训导师”。由发育生物学、围产期健康结果和医生-科学家培训领域的校内和校外专家组成的4人指导委员会和6人咨询委员会将就受训人员的选择和进展以及总体方案成功提供指导。