Mortality among injecting drugs users - a follow-up study of injecting drug user cohorts.

注射吸毒者的死亡率——注射吸毒者群体的后续研究。

• 批准号: nhmrc : 398501
• 负责人: A/Pr Mark Stoove
• 金额: $ 3.17万
• 依托单位: Turning Point Alcohol and Drug Centre
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2006
• 资助国家: 澳大利亚
• 起止时间: 2006-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mortality-injecting-drugs-user-cohorts/96288
• 关键词: Mortality; among; injecting; drugs; users

This study will follow-up injecting drug users that participated in research in the 1990s and 2000s to examine mortality rates in these groups over time. Identifying information from these studies will be cross-referenced with National Death Index data to determine participants that died and the dates of their death. This study will be the first in Australia to determine mortality rates over time in a defined cohort of injecting drug users outside drug treatment settings. Studying a defined group overcomes some of the problems associated with mortality rate estimates based simply on the number of injecting drug-related deaths. Although the number of deaths can be found, the number of people at risk of injecting drug-related death is unclear because of the hidden nature of drug use and the dynamic characteristics of drug use and drug markets. The examination of mortality trends among injecting drug users over time can provide insights regarding changes in drug use patterns and markets. For example, this study will examine changes in injecting drug use mortality across periods of high heroin availability in the late '90s and periods of interrupted heroin supply - the heroin 'drought' - from 2000 onwards. In addition, factors related to injecting drug-related mortality can be explored by comparing the characteristics of injecting drug users that died and those that survived, such as drug use and drug treatment histories, co-morbidities such as mental illness and socio-demographic backgrounds. This information can inform overdose prevention and harm reduction strategies by identifying individuals most at risk of injecting drug-related mortality. This study will also draw attention to the significant public health burden of injecting drug use. In addition, by comparing the results from this study with other similar studies from overseas, we can more reliably compare mortality among groups of Australian injecting drug users with their peers in other countries.

这项研究将对20世纪90年代和21世纪初参与研究的注射吸毒者进行随访，以检查这些群体随时间的死亡率。来自这些研究的识别信息将与国家死亡指数数据交叉引用，以确定死亡参与者及其死亡日期。这项研究将是澳大利亚第一个在药物治疗环境外确定注射吸毒者队列随时间的死亡率的研究。对一个确定的群体进行研究，克服了仅仅根据与注射毒品有关的死亡人数来估计死亡率的一些问题。虽然可以找到死亡人数，但由于吸毒的隐秘性以及吸毒和毒品市场的动态特点，面临注射毒品相关死亡风险的人数尚不清楚。对注射吸毒者长期死亡率趋势的审查可以提供有关吸毒模式和市场变化的见解。例如，本研究将检查90年代后期海洛因高供应量时期和2000年以后海洛因供应中断时期（海洛因“干旱”时期）注射吸毒死亡率的变化。此外，可以通过比较死亡和存活的注射吸毒者的特征，如吸毒和药物治疗史、精神疾病等合并症和社会人口背景，来探索与注射毒品有关的死亡率相关的因素。这些信息可以通过确定最有可能导致注射毒品相关死亡的个人，为预防过量用药和减少危害战略提供信息。这项研究还将提请注意注射吸毒的重大公共卫生负担。此外，通过将本研究的结果与国外其他类似研究的结果进行比较，我们可以更可靠地比较澳大利亚注射吸毒者群体与其他国家同龄人的死亡率。