Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy (KneeBRIGHT)

用于基于游戏的家庭治疗的膝关节生物反馈康复接口 (KneeBRIGHT)

• 批准号: 9794639
• 负责人: Eileen T. Krepkovich
• 金额: $ 83.27万
• 依托单位: BARRON ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-30 至 2022-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9794639
• 关键词: Activities of Daily Living; Address; Adherence; Architecture; Area; Award; Biofeedback; Certification; Clinic; Clinical Trials; Computer software; Degenerative polyarthritis; Development; Disease; Electrodes; Electromyography; Evidence based practice; Exercise; Exercise Therapy; Exhibits; Feasibility Studies; Feedback; Goals; Health Services Accessibility; Home environment; Insurance; Interview; Knee; Knee Osteoarthritis; Laboratories; Measures; Modeling; Motivation; Muscle; Outcome; Pain; Patient Monitoring; Patients; Performance; Phase; Physical Function; Production; Protocols documentation; Provider; Public Health; Recovery of Function; Rehabilitation therapy; Resistance; Risk; Safety; Small Business Innovation Research Grant; Symptoms; System; Technology; Teletherapy; Testing; Time; Torque; Training; Travel; United States; Universities; Validation; Video Games; Virginia; Wireless Technology; arthropathies; base; compliance behavior; cost; dashboard; design; disability; efficacy testing; evidence base; exercise regimen; exercise rehabilitation; experience; functional improvement; functional outcomes; functional status; improved; innovation; muscle strength; pain reduction; pain symptom; patient engagement; programs; prototype; quadriceps muscle; sensor; strength training; success; tool; usability

PROJECT SUMMARY/ABSTRACT Significance: The Knee Biofeedback Rehabilitation Interface for Game-based Home Therapy (“KneeBRIGHT”) system combines electromyography (EMG) biofeedback with video game therapy (VGT) to provide knee osteoarthritis (OA) patients with an engaging, effective tool for conducting rehabilitation exercises at home. KneeBRIGHT aims to motivate patients with knee OA to conduct regular muscle strengthening exercise through an engaging, EMG-driven video game therapy. The system combines wireless EMG electrodes that are convenient for patients to use in a home setting with software that provides automated guidance through evidence-based, progressive exercise routines. Importantly, these exercises are presented to the patient in the form of fun and engaging games to promote a positive experience and encourage continued adherence. Problem to be Addressed: OA is the leading cause of disability in the United States. Rehabilitation through quadriceps strengthening is a well-established treatment for patients with OA of the knee, but patient adherence to exercise routines is low due to lack of guidance regarding optimal protocols and lack of engagement during the repetitive routines that patients find tedious and boring. Long-Term Goal: Improve knee OA outcomes through effective and motivating rehabilitation exercises. Phase I Results: During the Phase I effort, a prototype KneeBRIGHT system was developed and verified in a laboratory setting. The feasibility testing with 19 knee OA patients demonstrated statistically significant increases in muscle activation, engagement levels, and duration of voluntary exercise during the KneeBRIGHT exercises when compared with exercises conducted with a conventional EMG biofeedback system. Phase II Hypotheses: The Phase II program will test the hypotheses that patients performing exercise routines using KneeBRIGHT will: (1) achieve superior muscle strength gain compared to a conventional EMG biofeedback protocol; and (2) exhibit increased adherence compared to the conventional system. Phase II Summary: Barron Associates (award-winning innovators in video game therapy) has partnered with the University of Virginia for this SBIR Phase II program to demonstrate efficacy and user acceptance of the KneeBRIGHT system. The specific objectives of the Phase II program are to: (1) develop the Phase II commercial KneeBRIGHT EMG modules; (2) develop the Phase II commercial KneeBRIGHT game software with adaptive exercise protocols and expanded game activities; (3) develop a provider dashboard to enable clinicians to monitor patient performance remotely; and (4) perform efficacy testing of muscle strength, functional improvement (via Knee Osteoarthritis Outcome Score), and adherence (when compared to a conventional system) with knee OA patients in a 12-week clinical trial. Impact: The system will have a significant overall impact on public health by increasing patient adherence to home exercise and thereby reducing pain symptoms and restoring physical function to knee OA patients.

项目总结/摘要 意义：用于游戏式家庭治疗的膝关节生物反馈康复界面（“KneeBRIGHT”） 该系统结合了肌电图（EMG）生物反馈和视频游戏治疗（VGT）， 为骨关节炎（OA）患者提供一种在家中进行康复锻炼的有效工具。 KneeBRIGHT旨在激励膝关节OA患者定期进行肌肉强化锻炼 通过一个引人入胜的，以肌电图为驱动的视频游戏疗法。该系统结合了无线EMG电极， 方便患者在家庭环境中使用， 循证的渐进式锻炼计划重要的是，这些练习是在 一种有趣和吸引人的游戏形式，以促进积极的体验并鼓励继续坚持。 要解决的问题：OA是美国残疾的主要原因。教养 股四头肌强化是膝关节OA患者的一种公认治疗方法，但患者 由于缺乏关于最佳方案的指导和缺乏 在病人觉得乏味和无聊的重复性程序中， 长期目标：通过有效和激励性的康复锻炼改善膝关节OA的结局。 第一阶段的结果：在第一阶段的工作中，开发了一个原型KneeBright系统，并在 实验室设置。对19例膝关节OA患者进行的可行性测试显示， 增加肌肉激活，参与水平，以及在KneeBRIGHT期间自愿运动的持续时间 与常规EMG生物反馈系统进行的练习相比， 第二阶段假设：第二阶段计划将测试患者进行日常锻炼的假设 使用KneeBright将：（1）与传统EMG相比，获得上级肌肉力量增益 生物反馈方案;和（2）与常规系统相比表现出增加的粘附性。 第二阶段总结：巴伦协会（屡获殊荣的视频游戏治疗创新者）已与 弗吉尼亚大学的SBIR第二阶段计划，以证明有效性和用户接受的 KneeBright系统。第二阶段计划的具体目标是：（1）开发第二阶段 商业化KneeBrightEMG模块;（2）开发第二阶段商业化KneeBrightTM游戏软件 与自适应锻炼协议和扩展的游戏活动;（3）开发一个提供商仪表板， 临床医生远程监测患者的表现;以及（4）执行肌肉力量的功效测试， 功能改善（通过膝关节骨关节炎结局评分）和依从性（与 常规系统）与膝关节OA患者在12周的临床试验中。 影响：该系统将通过提高患者对以下方面的依从性，对公共卫生产生重大的整体影响： 家庭锻炼，从而减轻疼痛症状并恢复膝关节OA患者的身体功能。