Pitt HIV-TB research and training program in India

皮特在印度的艾滋病毒结核病研究和培训项目

• 批准号: 9545359
• 负责人: Phalguni GUPTA
• 金额: $ 7.5万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-05-15 至 2020-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9545359
• 关键词: Acute; Advisory Committees; Area; Basic Science; Behavioral Sciences; Clinical; Clinical Sciences; Clinical Trials; Collaborations; Communicable Diseases; Community based prevention; Complement; Conduct Clinical Trials; Diagnosis; Diagnostic; Drug resistance; Epidemiology; Genetic Fingerprintings; Goals; Government; HIV; HIV/TB; Health Policy; Health Professional; Immunology; India; Infection; Institution; Joints; Knowledge; Laboratories; Leprosy; Malaria; Microbiology; Modality; Modernization; Needs Assessment; Physicians; Policies; Population; Program Evaluation; Public Health; Publishing; Recruitment Activity; Research; Research Institute; Research Personnel; Research Training; Rural Population; Science; Societies; Structure; Training; Training Programs; Travel; Tuberculosis; Universities; base; co-infection; health care service; health training; improved; innovation; multidisciplinary; novel; prevent; professor; programs; rapid diagnosis

 DESCRIPTION (provided by applicant): We propose to launch a Training and Research Program on HIV and TB in India at the University of Pittsburgh (Pitt-India-HTRTP). This new Pitt-India-HTRTP program will operate in collaboration with our partners at LEPRA Society (LepS), Hyderabad, India, one of the major research and clinical centers working on HIV and TB. Over the last couple of years, researchers from the University of Pittsburgh have been working with the investigators at LepS in conducting community based prevention studies and developing novel rapid diagnosis of TB. LepS is a 90-year old non-governmental organization providing healthcare services to rural populations of India inflicted with TB, Leprosy, HIV and Malaria. Recently, LepS started a research center to complement its clinical activities, but there is still an acute shortage of scholars and physicians with knowledge in modern research (laboratory, clinical, and behavioral sciences) to meet the ever-growing public health challenges of preventing and controlling drug resistant and normal TB in HIV infected populations. Based on comprehensive needs assessment by LepS management in conjunction with the ongoing research programs at the University of Pittsburgh, we identified multiple areas in which LepS workers can be trained to further their research capacity. Goal of the Pitt-India-HTRTP is to enhance the research capacity of LepS by training health care professionals in multidisciplinary cutting-edge research, publish pioneering research as well as participate in clinical trials to improve control of HIV and TB in India. The proposed training program will be led by Dr. Phalguni Gupta, Professor, Department of Infectious Diseases and Microbiology (IDM) and Co- Directors, Drs. Velpandi Ayyavoo, Professor of IDM with expertise in HIV, Anil Ojha, Assistant Professor of IDM with expertise in TB, and Todd Reinhart, Professor of IDM with expertise in HIV immunology. In addition, a joint Training Advisory Committee from the University of Pittsburgh, LepS, and the Government-affiliated research and health-policy institutions in India will provide ongoing critical evaluations of the program structure, recruitment, research plans, and placement. While most of the long-term training (leading to degrees) and short-term training will be at the University of Pittsburgh, some short-term training in clinical and basic sciences wil be provided through our partners at the National Institute for Research in Tuberculosis (NIRT), and Center for DNA fingerprinting and Diagnostics (CDFD) in India for only those trainees who cannot travel to the US. The proposed Program offers a unique opportunity for the coordinated, interdisciplinary training of health professionals from India in HIV/TB research in epidemiology, behavioral sciences, and laboratory sciences. Through this Pitt-India-HTRTP training program, health care professionals at LepS will gain knowledge about innovative research in HIV, TB and HIV/TB co-infections, and conduct clinical trials in these areas, sensitive diagnosis, and optimum treatment modalities against these infections. These enhancements will enable LepS to make informed policy decision on implementing effective control programs against HIV and TB.

 描述（由申请人提供）：我们建议在匹兹堡大学（Pitt-India-HTRTP）启动印度艾滋病毒和结核病培训和研究计划。这个新的皮特-印度-HTRTP计划将与我们在印度海得拉巴LEPRA协会（LepS）的合作伙伴合作，该协会是致力于艾滋病毒和结核病的主要研究和临床中心之一。在过去的几年里，匹兹堡大学的研究人员一直在与LepS的研究人员合作，进行基于社区的预防研究，并开发新的结核病快速诊断方法。LepS是一个有90年历史的非政府组织，为印度农村结核病、麻风病、艾滋病毒和疟疾患者提供医疗服务。最近，LepS启动了一个研究中心，以补充其临床活动，但仍然严重缺乏具有现代研究（实验室，临床和行为科学）知识的学者和医生，以应对预防和控制艾滋病毒感染人群中耐药性和正常结核病的日益增长的公共卫生挑战。根据LepS管理层的综合需求评估，结合匹兹堡大学正在进行的研究项目，我们确定了LepS工作人员可以接受培训以提高其研究能力的多个领域。Pitt-India-HTRTP的目标是通过培训多学科前沿研究的卫生保健专业人员，出版开创性研究以及参与临床试验来提高LepS的研究能力，以改善印度对艾滋病毒和结核病的控制。拟议的培训计划将由传染病和微生物学系教授Phalguni Gupta博士和联合主任领导，传染病和微生物学系教授Velpandi Ayyavoo博士具有艾滋病毒方面的专业知识，传染病和微生物学系助理教授Anil Ojha具有结核病方面的专业知识，传染病和微生物学系教授托德莱因哈特具有艾滋病毒免疫学方面的专业知识。此外，来自匹兹堡大学、LepS和印度政府附属研究和卫生政策机构的联合培训咨询委员会将对项目结构、招聘、研究计划和安置进行持续的关键评估。虽然大部分的长期培训（导致学位）和短期培训将在匹兹堡大学，一些临床和基础科学的短期培训将通过我们的合作伙伴在国家结核病研究所（NIRT）和DNA指纹识别和诊断中心（CDFD）在印度提供，只有那些学员谁不能前往美国。拟议的方案为来自印度的卫生专业人员在流行病学、行为科学和实验室科学方面的艾滋病毒/结核病研究提供了一个协调的跨学科培训的独特机会。通过Pitt-India-HTRTP培训计划，LepS的卫生保健专业人员将获得有关艾滋病毒，结核病和艾滋病毒/结核病合并感染创新研究的知识，并在这些领域进行临床试验，敏感诊断和针对这些感染的最佳治疗方式。这些改进将使LepS能够就实施有效的艾滋病毒和结核病控制计划做出明智的政策决定。