Mechanisms of cognitive interference from value-based choice conflict

基于价值的选择冲突的认知干扰机制

• 批准号: 9323534
• 负责人: AMITAI SHENHAV
• 金额: $ 28.72万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-01 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9323534
• 关键词: Affect; Alzheimer' s Disease; Area; Attention; Behavioral; Bipolar Disorder; Brain; Brain region; Centers of Research Excellence; Cognition; Cognitive; Conflict (Psychology); Cues; Data; Dependence; Detection; Disease; Electroencephalography; Event; Experimental Designs; Exposure to; Face; Feedback; Functional Magnetic Resonance Imaging; Future; Health; Human; Knowledge; Lateral; Light; Literature; Location; Maps; Measures; Mediating; Mental disorders; Methods; Modeling; Nature; Neuraxis; Outcome; Performance; Process; Reaction Time; Response to stimulus physiology; Role; Scalp structure; Schizophrenia; Signal Transduction; Source; Stimulus; Testing; Theoretical model; Time; Unipolar Depression; Visual Cortex; Visual attention; Work; area V1; base; behavioral response; executive function; extrastriate visual cortex; nervous system disorder; neuroimaging; response; retinotopic; selective attention; stimulus processing; visual processing

PROJECT SUMMARY (See instructions): Detection of and adaptation to stimulus-response conflict are critical and central aspects of human executive function. Yet, how such adaptation occurs is not well understood. Conflict occurs when multiple stimuli or multiple aspects of the same stimulus become associated with different behavioral responses. Behaviorally, conflict results in slower responses and increased errors. However, observers show moment-to-moment adaptation to conditions of conflict. An outcome of this adaptation is that subsequent conflicting stimuli have less of a negative impact on performance. It has been theorized that top-down control in response to conflict engages selective attention mechanisms to reduce additional conflict; this type of dynamic endogenous modulation has promise as a more ecologically valid model to study selective attention than classic experimental designs. However, the existing literature is inconsistent regarding the nature of these conflict driven attention effects. Some results point to multiple mechanisms of conflict driven attention operating at early stages of visual processing. Other results suggest that some attention mechanisms, such as distractor inhibition, for which there is substantial experimental evidence, may not play an important role in attention driven by contextual conflict. These same data do not support conflict related attention effects for early visual processing. This project proposes to use functional MRI and scalp electroencephalography to explore the brain mechanisms responsible for conflict adaptation, asking when, where and how these mechanisms affect visual processing. Specifically, we ask whether and how the brain uses selective visual attention to filter out unwanted information in response to conflict, whether conflict-driven perceptual modulation operates on feature and space based processing and whether such modulation is allocated in anticipation of impending stimulus events.

项目总结（见说明）：检测和适应刺激-反应冲突是人类执行功能的关键和中心方面。然而，这种适应是如何发生的还不清楚。当多个刺激或同一刺激的多个方面与不同的行为反应相关联时，就会发生冲突。从行为上讲，冲突会导致反应较慢和错误增加。然而，观察员们表现出对冲突条件的时时刻刻的适应。这种适应的结果是，随后的冲突刺激对表现的负面影响较小。理论上，自上而下的控制，以应对冲突，从事选择性注意机制，以减少额外的冲突，这种类型的动态内源性调制有希望作为一个更生态有效的模型来研究选择性注意比经典的实验设计。然而，现有的文献是不一致的这些冲突驱动的注意力效应的性质。一些结果指出，在视觉处理的早期阶段，冲突驱动的注意力的多种机制。其他结果表明，一些有大量实验证据的注意力机制，例如干扰物抑制，可能在上下文冲突驱动的注意力中不发挥重要作用。这些相同的数据并不支持早期视觉处理的冲突相关的注意力效应。本项目拟利用功能性磁共振成像和头皮脑电图来探索负责冲突适应的大脑机制，询问这些机制何时、何地以及如何影响视觉处理。具体来说，我们问大脑是否以及如何使用选择性视觉注意力来过滤掉不需要的信息，以响应冲突，是否冲突驱动的感知调制功能和空间为基础的处理，以及这种调制是否分配在预期即将发生的刺激事件。