Motor variability as a window into sustained attention

运动变异性是持续注意力的窗口

• 批准号: 9813024
• 负责人: Jeff Moher
• 金额: $ 35.71万
• 依托单位: CONNECTICUT COLLEGE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9813024
• 关键词: Affect; Attention; Attention deficit hyperactivity disorder; Basic Science; Behavior; Behavioral; Biomechanics; Brain; Brain Diseases; Cessation of life; Clinical; Clinical Research; Cognitive; Collection; Connecticut; Data; Data Analyses; Data Collection; Diagnosis; Disease; Environment; Equilibrium; Experimental Designs; Frequencies; Functional Magnetic Resonance Imaging; Future; Goals; Hand; Human; Impairment; Individual; Intervention; Journals; Knowledge; Link; Measurement; Measures; Medical Errors; Memory; Modeling; Modernization; Motor; Motor output; Movement; Mydriasis; Neurosciences Research; Output; Participant; Peer Review; Performance; Persons; Phase; Play; Population; Process; Research; Role; Schizophrenia; Science; Stroke; Students; Sum; Surgeon; System; Testing; United States; Universities; Work; academic review; base; career; cognitive process; college; cost; experience; experimental study; falls; improved; inattention; interest; neural network; novel; novel strategies; outcome prediction; practical application; response; selective attention; stroke recovery; summer research; sustained attention; symposium; systems research; undergraduate student

Project Summary Attention and action are often studied in isolation. However, recent research has highlighted the extent to which attention and action overlap in both behavioral and brain mechanisms. Thus, to advance knowledge in these fields, it is valuable to study attention and action as a combined system. In the current proposal, we will examine the link between sustained attention and action output. First, we will determine whether drifts in sustained attention that occur when a participant loses focus are correlated with increased variability in motor output. In other words, if a person’s motor movements become less consistent, does this suggest that they are losing focus? Second, we will examine whether brain networks previously linked with sustained attention are also related to motor output variability. If this relationship is observed, it would provide further converging evidence for a strong link between sustained attention and motor output. Finally, we will examine whether and how the physical demands of an action response can influence sustained attention. That is, if more demanding actions are required, is it easier to maintain focused attention? Data obtained from the current proposal will provide new empirical and theoretical knowledge about attention and action systems. In addition, there are valuable practical applications that would arise from the proposed results. For example, the ability to diagnose when a person is losing focus by measurements of simple motor movements would be highly vaulable. Finally, a number of brain disorders are known to involve deficits in attention and/or action, including ADHD, schizophrenia, and stroke. Results from the proposed basic research may provide important knowledge for future approaches in both diagnosis and treatments of these and other diseases involving attention and/or action. Undergraduate students at Connecticut College will play in active role in all phases of the proposed research. These students will be involved in experimental design, data collection, data analysis, and the presentation of the results both at national conferences and in peer-reviewed academic journals. The proposal will provide a unique opportunity for students to conduct functional magnetic resonance imaging (fMRI) research at Brown University during summer research sessions. fMRI research is at the forefront of modern human neuroscience research, and these students will gain direct experience both with the collection and analysis of fMRI data. These opportunities will significantly strengthen the research environment at Connecticut College and be particularly valuable for Connecticut College undergraduates interested in a future career in the sciences.

项目摘要 注意和动作经常被孤立地研究。但是，最近的研究强调了 行为和大脑机制都重叠的注意力和动作重叠。那就促进知识 这些领域，将注意力和行动作为一个组合系统很有价值。 在当前的提案中，我们将研究持续关注和动作输出之间的联系。首先，我们会的 确定当参与者失去焦点与关联相关时，是否会持续关注的漂移 电动机输出的变化增加。换句话说，如果一个人的运动运动变得不一致， 这是否表明他们正在失去关注？其次，我们将检查以前是否以前 与持续注意的关联也与电动机输出变异性有关。如果观察到这种关系， 将提供进一步的融合证据，以持续关注和电动机输出之间存在牢固的联系。 最后，我们将研究动作反应的物理要求以及如何影响持续的 注意力。也就是说，如果需要更苛刻的行动，是否更容易保持集中注意力？ 从当前建议获得的数据将提供有关注意的新经验和理论知识 和动作系统。此外，还有一些有价值的实用应用程序将由拟议的 结果。例如，何时通过测量简单电动机失去注意力的诊断能力 运动将是高度验证的。最后，已知许多脑部疾病涉及定义 注意和/或动作，包括多动症，精神分裂症和中风。拟议的基础研究的结果 可以为未来的诊断和治疗方法提供重要的知识 疾病涉及注意和/或行动。 康涅狄格学院的本科生将在拟议研究的所有阶段中发挥积极作用。 这些学生将参与实验设计，数据收集，数据分析以及介绍 在国家会议和同行评审的学术期刊上的结果。该提案将提供 学生在布朗进行功能磁共振成像（fMRI）研究的独特机会 夏季研究期间的大学。 fMRI研究处于现代人类神经科学的最前沿 研究，这些学生将通过FMRI数据的收集和分析获得直接的经验。 这些机会将大大加强康涅狄格学院的研究环境，并成为 对于康涅狄格大学的本科生特别有价值，对科学的未来职业感兴趣。