Research Design, Epidemiology and Biostatistics Core

项目概要/摘要：研究设计、流行病学和生物统计学核心 美国印第安人-阿拉斯加土著临床和转化研究中心（AI-AN） CTRC）研究设计、流行病学和生物统计学（RDEB）核心是提供RDEB服务， 蒙大拿州和阿拉斯加州临床和转化研究的设计和分析资源。这些 这些研究将致力于改善美国印第安人和阿拉斯加原住民（AI/AN）的健康状况 生活在这两个州RDEB核心是学术机构之间的独特合作努力 蒙大拿州（蒙大拿州立大学[MSU]和蒙大拿大学[UM]）和阿拉斯加州（阿拉斯加大学 安克雷奇[UAA]和费尔班克斯[UAF]），以及阿拉斯加的部落健康组织，阿拉斯加土著部落 健康联盟（ANTHC）和中南部基金会（SCF），形成全州系统的中心 阿拉斯加原住民的医疗保健。 RDEB核心主任将设在ANTHC，核心将通过中央管理 ANTHC的办公室。一名联合主任将设在密歇根州立大学。ANTHC是一个部落健康组织联盟， 阿拉斯加，它提供整个阿拉斯加部落卫生系统的卫生服务。这些服务包括 支持临床和转化研究（CTR），并支持阿拉斯加本土流行病学中心。 RDEB核心成员将包括具有CTR经验的临床医生、流行病学家和生物统计学家。 RDEB核心将：（1）在蒙大拿州建立一个流行病学家和生物统计学家的可访问网络， 阿拉斯加支持调查人员申请并通过试点项目计划核心资助;（2）增加 在阿拉斯加州和蒙大拿州从事CTR的个人劳动力， 为有兴趣培养CTR技能并获得知识的学生和研究人员提供实习机会 在公共卫生竞技场的经验;和（3）协调年度会议，重点是特定的人工智能/人工智能健康 问题，汇集生物统计学家，流行病学家，研究调查员，临床提供者，AI/AN 专家和领导人以及国家疾病特异性专家，以解决研究设计和生物统计 在阿拉斯加州和蒙大拿州进行CTR时面临的挑战。 通过这些机制，RDEB核心将促进CTR在蒙大拿州的增长和发展 和阿拉斯加，加强这两个州的CTR劳动力，并加快科学翻译 这一发现改善了美国印第安人和阿拉斯加土著人的健康状况。 PHS 398/2590（Rev.06/09）

Project Summary/Abstract: Research Design, Epidemiology, and Biostatistics Core The purpose of the American Indian-Alaska Native Clinical and Translational Research Center (AI-AN CTRC) Research Design, Epidemiology, and Biostatistics (RDEB) Core is to provide RDEB services and resources for the design and analysis of clinical and translational studies in Montana and Alaska. These studies will target research efforts to improve the health of American Indian and Alaska Native (AI/AN) people living in these two IDeA states. The RDEB Core is a unique collaborative effort between academic institutions in Montana (Montana State University [MSU] and University of Montana [UM]) and Alaska (University of Alaska Anchorage [UAA] and Fairbanks [UAF]), and Tribal health organizations in Alaska, the Alaska Native Tribal Health Consortium (ANTHC) and Southcentral Foundation (SCF), which form the hub of the statewide system of health care for Alaska Native people. The RDEB Core director will be based at ANTHC and the Core will be administrated through a central office at ANTHC. A Co-director will be based at MSU. ANTHC is a consortium of Tribal Health Organizations in Alaska which provides health services throughout the Alaska Tribal Health System. These services include support for clinical and translational research (CTR) and support for the Alaska Native Epidemiology Center. RDEB Core membership will include clinicians, epidemiologists and biostatisticians with experience in CTR. The RDEB core will: (1) create an accessible network of epidemiologists and biostatisticians in Montana and Alaska to support investigators applying for and funded through the Pilot Projects Program Core; (2) increase the workforce of individuals engaged in CTR in Alaska and Montana through provision of didactic and internship opportunities for students and researchers interested in building their CTR skills and gaining experience in the public health arena; and (3) coordinate annual meetings focused on specific AI/AN health issues, bringing together biostatisticians, epidemiologists, research investigators, clinical providers, AI/AN experts and leaders and national disease specific experts to address the research design and biostatistical challenges faced in doing CTR in Alaska and Montana. Through these mechanisms, the RDEB core will facilitate the growth and development of CTR in Montana and Alaska, enhance the CTR workforce in these two IDeA states, and accelerate the translation of scientific discovery into improved health for American Indian and Alaska Native people. PHS 398/2590 (Rev. 06/09) Page Continuation Format Page