NExT NX232-107-158-006 TO#3 Milestone 3 (base) - PK & Bioavail Stud w/Selected Anticancer Compounds in Mice, PK & Pharm Evals of Agents Being Developed for Cancer Patients, HHSN261201600024I/HHSN26100

本任务单的目的是表征小分子候选抗癌化合物在小鼠体内的血浆药代动力学（PK）和生物利用度，以支持NExT项目团队。研究结果的快速转变是必需的。在此任务订单下，有九(9)个额外研究选项。需要提供包含所有化合物研究数据的综合电子表格（Excel）。这将使NExT项目团队能够对化合物进行全面分析。

The purpose of this Task Order is to characterize the plasma pharmacokinetics (PK) and bioavailability of small molecule candidate anticancer compounds in mice in support of NExT project team(s). Rapid turn-around of study results is required. There are nine (9) options for additional studies under this task order. Delivery of a comprehensive spreadsheet (Excel) containing data for all compounds studied is required. This will allow the NExT project team to conduct a comprehensive analysis across compounds.