RR&D Research Career Scientist Award Application

RR

基本信息

  • 批准号:
    9394573
  • 负责人:
  • 金额:
    --
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2017
  • 资助国家:
    美国
  • 起止时间:
    2017-07-01 至 2022-06-30
  • 项目状态:
    已结题

项目摘要

Problem. Neurological disease and injury are major causes of disability, reflecting the need for more effective interventions. Additionally, accounting for the aging Veteran population, there is a projected 20% increase in disability for individuals age 85 and older, within the next 10 years. For example, approximately 6,000 VA annual admissions are for stroke, and at least 50% have serious, long term disability. Equally compelling statistics exist for traumatic brain injury (TBI) and other neurological diseases and injury. Research Activities and Overarching Goals. In strong support of the VHA Vision 2020 Strategic Plan and the RR&D mission, Dr. Daly is Director of the VA BRRC, whose mission is as follows: Discover mechanisms of pathology and impairment presenting obstacles to neural function, and generate innovative treatments to potentiate neural plasticity and neural network reorganization that will substantially improve motor, cognitive, and emotion function affected by neurologic disease or injury, sufficient to enhance quality of life and return to society and life role participation. To that end, Dr. Daly’s empowering BRRC leadership has attracted an interdisciplinary critical mass of electrical and biomedical engineers, biomechanists, neurologists, physical and occupational therapists, experimental and clinical neuropsychologists, exercise and neuromuscular physiologists, neuroscientists, and chemical and biophysicists. Significant discoveries have included information regarding the pathologies underlying neural dysfunction and innovative methods for restoring neural control of motor, cognitive, and emotion function for those with TBI, stroke, Parkinson’s disease, spinal cord injury, and multiple sclerosis. Supporting the VHA Mission and goals, and in addition to her BRRC leadership, Dr. Daly directs the Cognitive and Motor Learning Research Program, whose mission is to identify, engage, and restore the neural control that drives recovery of motor function in stroke survivors. Goals of currently ongoing studies are as follows: 1. Identify brain pattern changes that drive motor recovery. 2. Generate novel treatment methods that more accurately target pathology and impairment. 3. Apply motor learning principles that engage brain plasticity mechanisms allowing for productive practice of progressively more normal coordinated gait and upper limb function. 4. Generate and test treatment modules for gait components and upper limb function components. 5. Test gait and upper limb coordination treatment protocols in the clinical environment. Discoveries include the following: development and successful testing of a gait coordination training protocol that is clinically and statistically effective in chronic moderately impaired stroke survivors; successful feasibility pilot testing of a unique two-year care program for gait coordination, mobility, and fitness in stroke survivors; brain activation changes identified that drive upper limb motor recovery; development and successful testing of an upper limb function training protocol that is clinically and statistically effective in chronic moderately/severely impaired stroke survivors; necessary essential content of coordination training protocols includes long-duration, intensive coordination practice of finely incremental progression through a difficulty hierarchy.
问题。神经系统疾病和损伤是致残的主要原因,反映出需要更多的治疗

项目成果

期刊论文数量(0)
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会议论文数量(0)
专利数量(0)

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JANIS J. DALY其他文献

JANIS J. DALY的其他文献

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{{ truncateString('JANIS J. DALY', 18)}}的其他基金

Optima Human Performance System (HPS) for Measurement of Innovative Gait Recovery Methods
用于测量创新步态恢复方法的 Optima 人体表现系统 (HPS)
  • 批准号:
    8950179
  • 财政年份:
    2015
  • 资助金额:
    --
  • 项目类别:
Combined Cognitive and Gait Training
认知和步态联合训练
  • 批准号:
    8500036
  • 财政年份:
    2012
  • 资助金额:
    --
  • 项目类别:
Combined Cognitive and Gait Training
认知和步态联合训练
  • 批准号:
    9172712
  • 财政年份:
    2012
  • 资助金额:
    --
  • 项目类别:
Combined Cognitive and Gait Training
认知和步态联合训练
  • 批准号:
    9130599
  • 财政年份:
    2012
  • 资助金额:
    --
  • 项目类别:
Combined Cognitive and Gait Training
认知和步态联合训练
  • 批准号:
    8270120
  • 财政年份:
    2012
  • 资助金额:
    --
  • 项目类别:
Combined Cognitive and Gait Training
认知和步态联合训练
  • 批准号:
    8957023
  • 财政年份:
    2012
  • 资助金额:
    --
  • 项目类别:
Non-Invasive Brain-Signal Training To Induce Motor Control Recovery after Stroke
非侵入性脑信号训练可诱导中风后运动控制恢复
  • 批准号:
    8045658
  • 财政年份:
    2008
  • 资助金额:
    --
  • 项目类别:
Non-Invasive Brain-Signal Training To Induce Motor Control Recovery after Stroke
非侵入性脑信号训练可诱导中风后运动控制恢复
  • 批准号:
    8459232
  • 财政年份:
    2008
  • 资助金额:
    --
  • 项目类别:
Non-Invasive Brain-Signal Training To Induce Motor Control Recovery after Stroke
非侵入性脑信号训练可诱导中风后运动控制恢复
  • 批准号:
    7514987
  • 财政年份:
    2008
  • 资助金额:
    --
  • 项目类别:
Non-Invasive Brain-Signal Training To Induce Motor Control Recovery after Stroke
非侵入性脑信号训练可诱导中风后运动控制恢复
  • 批准号:
    7680226
  • 财政年份:
    2008
  • 资助金额:
    --
  • 项目类别:
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