Training of Junior Faculty for Careers in Omics of Lung Diseases

肺部疾病组学初级教师职业培训

• 批准号: 9283609
• 负责人: ROBERT L. GROSSMAN
• 金额: $ 33.89万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-01 至 2018-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9283609
• 关键词: Area; Asthma; Biology; Chicago; Childhood; Communities; Complex; Data Collection; Data Set; Diabetes Mellitus; Disease; Educational Curriculum; Enrollment; Environmental Risk Factor; Epigenetic Process; Faculty; Genetic; Goals; Hypertension; Informatics; Learning; Lung; Lung diseases; Mentors; Monitor; Names; Organ; Pathway interactions; Physicians; Program Development; Pulmonary Fibrosis; Research; Research Training; Resources; SECTM1 gene; Scientist; Series; Sleep Apnea Syndromes; Syndrome; Training; Training Programs; Translating; Universities; Work; biological systems; career; career development; clinical phenotype; disease diagnosis; experience; health economics; insight; programs; respiratory; respiratory health; skills; tool; training opportunity

DESCRIPTION (provided by applicant): The Univ of Chicago K12 Career Development Program in Omics of Lung Diseases will establish a new pathway for the further training of physician and non-physician junior faculty scientists in the integration and analysis of large data sets to gain new insights into the pathogenetic mechanisms underlying lung diseases and translate these insights into tools for disease diagnosis, treatment, and monitoring. Only junior faculty will be enrolled as Scholars in this 2-year training program, which requires at least 80% commitment. Each will engage in an individualized curriculum of classroom courses and hands-on training, and will apply these skills in a multidimensional, highly-mentored research learning experience. The pro- gram focuses on three respiratory health problems - asthma, childhood sleep disordered breathing, and pulmonary fibrosis - because of their enormous health and economic importance's and the deep and broad expertise at UC in these areas; and because each is paradigmatic of common but complex disease syndromes in which many different combinations of genetic, epigenetic, and environmental factors conspire to generate a series of closely similar clinical phenotypes that are collectively named as single entities. Recognizing the commonalities of seemingly disparate diseases, we include a fourth training pathway that emphasizes a systems biological approach that spans all three disease groups. An explicit goal of this program that its training opportunities and benefits will extend beyond the relatively few Scholars whose stipends it will provide, into the larger respiratory biology community at our University and in Chicago, and to young scientists pursuing omics/informatics approaches to common, complex diseases whose principal target organs are other than the lung (e.g., diabetes, hypertension, etc). We expect that at least 7 Scholars will be trained in this program, which leverages extensive data collections and other research and training resources already available at the University, and brings faculty into the study of respiratory disease who had not previously worked in this area.

描述（由申请人提供）：芝加哥大学K12肺部疾病组学职业发展计划将为医师和非医师初级教师科学家在大数据整合和分析方面的进一步培训建立新的途径

项目成果

Neonatal Thrombocytopenia: Etiology and Diagnosis.

• DOI: 10.3928/00904481-20150710-11
• 发表时间: 2015-07
• 期刊: Pediatric annals
• 影响因子: 1.1
• 作者: Sillers L;Van Slambrouck C;Lapping-Carr G
• 通讯作者: Lapping-Carr G

Insights into Selected Aspects of Pediatric Sleep Medicine.

深入了解儿科睡眠医学的某些方面。

• DOI: 10.1164/rccm.201502-0279rr
• 发表时间: 2015
• 期刊: American journal of respiratory and critical care medicine
• 影响因子: 24.7
• 作者: Gileles-Hillel,Alex;Philby,MonaF;Lapping-Carr,Gabrielle
• 通讯作者: Lapping-Carr,Gabrielle

Anemia in the Neonate: The Differential Diagnosis and Treatment.

• DOI: 10.3928/00904481-20150710-08
• 发表时间: 2015-07
• 期刊: Pediatric annals
• 影响因子: 1.1
• 作者: Nassin ML;Lapping-Carr G;de Jong JL
• 通讯作者: de Jong JL

From granuloma to fibrosis: sarcoidosis associated pulmonary fibrosis.

• DOI: 10.1097/mcp.0000000000000301
• 发表时间: 2016-09
• 期刊: Current opinion in pulmonary medicine
• 影响因子: 3.3
• 作者: Bonham CA;Strek ME;Patterson KC
• 通讯作者: Patterson KC