Advanced Research Institute in Mental Health and Aging

“心理健康和老龄化高级研究所（ARI）”的总体目标是提高 成功转型为具有高影响力的独立调查员的早期职业教师数量 心理健康和老龄化方面的研究，推进 NIMH 战略计划的所有四个战略目标。的 人口正在迅速老龄化——无论是在寿命、绝对数量还是相对于其他年龄层方面——无论是在 美国和世界大部分地区。这些人口变化既为新人带来了挑战，也带来了机遇。 几代研究人员解释了衰老对精神疾病的影响，并减少了个人 以及老年人精神疾病的社会负担。关注心理健康的调查人员数量 相对于科学和公共卫生挑战的规模而言，老龄化的影响很小。 ARI 将提供早期职业生涯 为教师提供指导性教育计划，以促进他们过渡到：目标 1（独立调查员） 通过获得 NIH R01 级（或同等）资助来衡量，其次是通过其他方式获得研究资助 研究证明，NIH 机制或联邦拨款计划以及目标 2（科学领袖） 指导、保留活跃研究人员、出版物、学术推广、参与团队科学、 和科学服务（例如 NIH 研究部门。ARI 国家指导网络是一个多学科的网络） 由高级和中期职业科学家组成的团队，他们具有互补的技能，涵盖了翻译领域 大脑、干预和实施科学。 ARI 教育计划支持 16 名早期职业人士 每年都有教师（称为学者）参加，每位学者参与两年。关键要素包括： 持续的指导侧重于拨款写作和职业发展，与生物统计学家的咨询，以及 专业发展。该计划包括每年一次的面对面春季静修、结构化的长途旅行 后续行动和基于网络的职业发展研讨会。该程序的新功能包括 1. 增强 为导师和学者提供正式导师培训和资源的教育计划；和 2. 通过指导研究员计划建立生物统计咨询支持。公共卫生影响： 老年人心理健康需求未得到满足是一个重大的公共卫生问题，不仅影响到老年人 患有精神障碍，但他们的家庭、护理提供者、社区以及提供和治疗精神障碍的机构 支付护理费用。研究挑战包括减轻老年人精神疾病的负担，同时也 解释衰老过程如何影响精神疾病的风险、表现和结果 整个成人的一生。应对这一挑战的研究能力在很大程度上取决于持续不断的研究 来自各个翻译领域的新独立研究人员丰富了该领域 最先进的培训和创新理念。 ARI 将通过开发下一代技术来建立这种能力 独立研究人员和科学领导者在心理健康和衰老方面进行高影响力的研究。

The overarching goal of the "Advanced Research Institute (ARI) in Mental Health and Aging” is to increase the number of early-career faculty successfully transitioning to independent investigators conducting high impact research in mental health and aging that advances all four strategic objectives of the NIMH Strategic Plan. The population is aging rapidly – in terms of longevity, absolute numbers and relative to other ages -- both in the US and in much of the world. These demographic changes offer both challenges and opportunities for new generations of researchers to explicate the contribution of aging to mental illness and to reduce the personal and societal burden of mental illness in older adults. The number of investigators focused on mental health and aging is small relative the size of the scientific and public health challenges. ARI will provide early-career faculty a mentored, educational program to foster their transition to: Aim 1 (Independent Investigators) measured by obtaining NIH R01-level (or equivalent) funding and, secondarily, research funding through other NIH mechanisms or federal grant programs, and Aim 2 (Scientific Leaders) as evidenced by research mentoring, retention as active researchers, publications, academic promotion, participation in team science, and scientific service (e.g., NIH Study sections. The ARI national Mentoring Network is a multi-disciplinary team of senior and mid-career scientists with complementary skills which span the translational spectrum of brain, interventions and implementation science. The ARI Educational Program supports 16 early-career faculty (called Scholars) annually with each Scholar’s participating for two years. Key elements include: sustained mentoring focused on grant-writing and career development, consultation with biostatisticians, and professional development. The program includes an annual in-person Spring Retreat, structured long-distance follow-up, and web-based career development seminars. New features to this program include 1. enhancing the educational program with formal mentor training and resources for both Mentors and Scholars; and 2. building biostatistical consultation support through a mentored fellows program. Public Health Impact: The unmet mental health needs of older adults is a significant public health problem that affects not only those who suffer from mental disorders but their families, care providers, communities, and institutions that deliver and pay for care. The research challenge includes reducing the burden of mental illness in older adults while also explicating how the process of aging contributes to the risk, expression, and outcomes of mental illness throughout the adult life span. The capacity of research to meet this challenge rests largely on ongoing enrichment of the field with new independent investigators from across the translational spectrum with state-of- the-art training and innovative ideas. ARI will build this capacity by developing the next generation of independent investigators and scientific leaders conducting high impact research in mental health and aging.