Brief couples-based alcohol intervention for HIV-infected MSM and their primary partners
对感染艾滋病毒的男男性行为者及其主要伴侣进行简短的基于夫妻的酒精干预
基本信息
- 批准号:9345106
- 负责人:
- 金额:$ 24.58万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-05-10 至 2021-04-30
- 项目状态:已结题
- 来源:
- 关键词:AIDS preventionAIDS/HIV problemAddressAdherenceAlcohol consumptionAlcoholsBisexualCounselingCouplesDataDevelopmentDrug usageElementsFoundationsFutureGaysGoalsHIVHealthHealth behaviorHeavy DrinkingIndividualInterventionInterviewLinkLiver diseasesManualsModelingMotivationOutcomeParticipantPatientsPopulationPreventive InterventionProceduresProtocols documentationPublic HealthPublishingRandomizedRandomized Clinical TrialsRandomized Controlled TrialsReportingResearchResourcesRiskSample SizeSelf EfficacySpecialistStructureSubgroupSubstance Use DisorderTarget PopulationsTestingTimeTrainingTreatment EfficacyUnited StatesViralViral Load resultWorkalcohol abstinencealcohol abuse therapyalcohol interventionantiretroviral therapyarmbasebehavior changebrief motivational interventioncognitive functioncomparative efficacycost effectivenessdrinkingdrinking behaviorevidence basefollow-upimprovedinformantinsightintervention participantsliver functionmalemembermenmen who have sex with menmortalitymotivational interventionproblem drinkerrecruitreduced alcohol usesatisfactionsexsex risksexual risk takingskillssocialtheoriestherapy adherencetherapy developmentuptakeviral detection
项目摘要
Project Summary
Heavy alcohol use in HIV-infected patients contributes to suboptimal adherence to antiretroviral therapy
(ART), greater sexual risk taking, higher viral loads, and worsened liver and cognitive functioning. Gay,
bisexual, and other men who have sex with men (MSM) continue to represent almost half of all HIV/AIDS
cases in the United States, and heavy drinking is particularly high among this HIV-infected sub-group. Brief
motivational interventions have been shown to reduce alcohol consumption among HIV-infected MSM;
however, these individual-level interventions have demonstrated only modest effects in reducing drinking in
this population, indicating that sustained behavior change requires attending to social and interpersonal
contexts as well. To date, there are no existing brief, couples-based interventions to address heavy alcohol
use among HIV-infected MSM and their primary partners that do not require alcohol abstinence treatment
goals. Furthermore, there are no published data on the extent to which changes in couples alcohol use
relate to key HIV-related outcomes (ART adherence, viral suppression, sexual risk). The overall aim of this
project is to develop and test the feasibility, acceptability, and preliminary efficacy of a brief couples-based
motivational intervention to address heavy alcohol use among HIV-infected MSM and their primary partner.
This treatment development project builds on our individual-level motivational intervention (MI) with HIV-
infected MSM by using components from our significant other-involved motivational intervention (SO-MI)
and couples-based HIV prevention interventions, and seeks to provide insights into the mechanisms of
couple-level behavior change, including motivation, individual and dyadic self-efficacy, and partner support.
A two-step sequence of treatment development will be used to achieve these aims. Stage 1a includes
interviews with key informants (N = 15 couples), manual development, therapist training, and a one-arm
pilot with qualitative exit interviews (N = 12 couples). Stage 1b consists of a small-randomized clinical trial in
which 50 heavy drinking HIV-infected MSM will be randomly assigned to either couples intervention, which
involves participation of their partner, or to the existing individual intervention, which does not. Both
conditions will consist of four sessions conducted over a one-month period. Participants will be interviewed
at baseline, and 3-months and 6-months. Findings will provide data on the feasibility, acceptability and
preliminary efficacy of the couples-based motivational intervention to reduce alcohol use among HIV-
infected MSM and their primary partners. If this research shows initial promise, we will use findings to
support an R01 application to test the intervention efficacy in a fully powered randomized controlled trial.
This research could provide a foundation for improving the health of HIV-infected heavy drinking MSM.
项目总结
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Kristi E Gamarel其他文献
Kristi E Gamarel的其他文献
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{{ truncateString('Kristi E Gamarel', 18)}}的其他基金
A multi-level approach to improve HIV prevention and care for transgender women of color
改善跨性别有色人种女性艾滋病毒预防和护理的多层次方法
- 批准号:
10767072 - 财政年份:2023
- 资助金额:
$ 24.58万 - 项目类别:
Strengthening community responses to economic vulnerability and HIV inequities
加强社区应对经济脆弱性和艾滋病毒不平等问题的对策
- 批准号:
10476669 - 财政年份:2022
- 资助金额:
$ 24.58万 - 项目类别:
A multi-level approach to improve HIV prevention and care for transgender women of color
改善跨性别有色人种女性艾滋病毒预防和护理的多层次方法
- 批准号:
10546317 - 财政年份:2022
- 资助金额:
$ 24.58万 - 项目类别:
Strengthening community responses to economic vulnerability and HIV inequities
加强社区应对经济脆弱性和艾滋病毒不平等问题的对策
- 批准号:
10625694 - 财政年份:2022
- 资助金额:
$ 24.58万 - 项目类别:
Addressing violence and HIV cascade of care outcomes among transgender women
解决跨性别女性中的暴力和艾滋病毒护理结果连锁反应
- 批准号:
9912488 - 财政年份:2020
- 资助金额:
$ 24.58万 - 项目类别:
A multicomponent intervention to address gender-based violence in HIV prevention for women
采取多方干预措施解决妇女艾滋病毒预防中基于性别的暴力问题
- 批准号:
10005664 - 财政年份:2020
- 资助金额:
$ 24.58万 - 项目类别:
Addressing violence and HIV cascade of care outcomes among transgender women
解决跨性别女性中的暴力和艾滋病毒护理结果连锁反应
- 批准号:
10077889 - 财政年份:2020
- 资助金额:
$ 24.58万 - 项目类别:
A couples-based approach to HIV prevention for transgender women and their male partners
针对跨性别女性及其男性伴侣的基于夫妇的艾滋病毒预防方法
- 批准号:
10412053 - 财政年份:2018
- 资助金额:
$ 24.58万 - 项目类别:
A couples-based approach to HIV prevention for transgender women and their male partners
针对跨性别女性及其男性伴侣的基于夫妇的艾滋病毒预防方法
- 批准号:
10170430 - 财政年份:2018
- 资助金额:
$ 24.58万 - 项目类别:
Brief couples-based alcohol intervention for HIV-infected MSM and their primary partners
对感染艾滋病毒的男男性行为者及其主要伴侣进行简短的基于夫妻的酒精干预
- 批准号:
9922838 - 财政年份:2018
- 资助金额:
$ 24.58万 - 项目类别: