Development of the Enteric Nervous System: Cells, Signals, Genes, and Therapy
肠神经系统的发育:细胞、信号、基因和治疗
基本信息
- 批准号:9541099
- 负责人:
- 金额:$ 1.96万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-02-15 至 2019-01-31
- 项目状态:已结题
- 来源:
- 关键词:AreaAttentionAwardBirdsBostonCell TherapyCellsCellular biologyChildhoodCollaborationsCongenital MegacolonCountryDevelopmentDevelopmental BiologyDiagnosisDiseaseDistalEnteralEnteric Nervous SystemEventFacultyFosteringFunctional disorderFutureGastroenterologistGoalsGrantGrowthHong KongHumanInternationalIntestinesKnowledgeLeadLondonMaintenanceMentorsMentorshipMolecular BiologyMorbidity - disease rateNeuropathyNew YorkParticipantPathologistProductivityResearch PersonnelRodentScienceScientistSignal TransductionStem cellsStructureSurgeonTimeTravelUnderrepresented MinorityWomanZebrafishbasecareercareer developmentcostdesignexpectationgene therapygenetic analysisinterestmeetingsmembernervous system developmentnovelpublic health relevancesenior facultysuccesssymposiumsystems research
项目摘要
Project Summary/Abstract
Over the past 20 years, remarkable progress has been made in our understanding of the enteric nervous system
(ENS) and of the congenital and acquired neurointestinal diseases that result from abnormal development or
maintenance of the ENS. Many of the advances in understanding ENS development have been made by cell,
molecular, and developmental biology studies and genetic analyses using a variety of species, including avians,
rodents, zebrafish, and humans. These fundamental studies have contributed not only a detailed appreciation of
the complexities of ENS development, but are now also yielding novel opportunities to develop cell-based
therapies for treating enteric neuropathies.
Researchers studying ENS development gathered in New York in 2006 for their first international symposium.
This triennial meeting was subsequently held in London (2009), Hong Kong (2012), and Rotterdam (2015). The
symposium brings together clinicians and researchers, including developmental and cell biologists, pathologists,
geneticists, physiologists, pediatric gastroenterologists and surgeons, and stem cell researchers, who all share
a common interest in the development and pathophysiology of the enteric nervous system and the diagnosis
and treatment of neurointestinal diseases. All of the Symposia have been very successful, each hosting
approximately 150 participants from 20 different countries from around the world. The 5th International
Symposium on “Development of the Enteric Nervous System: Cells, Signals, Genes and Therapy” will be held
in Boston in April, 2018. This will be the first meeting focused on ENS development to be held in the U.S. in 12
years and builds on the success of the prior meetings and the growing importance of ENS research.
The specific aims of this R13 application are as follows: (1) To encourage the participation of young investigators,
particularly women and minorities under-represented in science, at this 5th International Symposium by offering
10 Travel Awards to offset registration costs and travel expenses; and (2) To enhance the likelihood of long-term
success for young investigators pursuing academic careers by establishing mentored relationships with select
faculty and members of the meeting’s Organizing Committee. It is our expectation that this meeting will help to
build lasting mentorship and collaborations that will help to advance the career development of the Travel Award
recipients.
项目总结/文摘
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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ALLAN M GOLDSTEIN其他文献
ALLAN M GOLDSTEIN的其他文献
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