Program Integration and Management

项目摘要--计划集成和管理 P01资助申请包括四个由研究人员发起和领导的地理研究项目 不同的地点与围绕前列腺癌转移主题构建的两个核心资源相互作用。 我们的P01结合了多学科的专业知识和最先进的研究项目，并由 领先的机构在我们对前列腺癌诱因的理解方面取得了成功的进展 转移。此应用程序中建议的项目和核心高度集成，并准备 最大限度地发挥方案项目拨款机制的优势，实现其总体目标。这个多中心 结构既是P01的最大优势，也是一项挑战。行政部门将特别重视 重要的是，它将提供协调的管理结构，允许每个参与机构 有效地互动和沟通。 提出了一种灵活的、高度互动的管理结构，通过这种结构，研究计划可以相互协作 可以不断地监测发展和进展情况。计划集成的总体目标和 管理是为以下目的提供领导、指导、协调和行政服务 提高研究生产力，保持高效的研究环境。一个重要的目标 将通过项目之间的互动促进思想交流和促进合作 领导、核心董事和研究小组的所有成员。为了实现总体目标， 计划集成与管理将重点关注以下主要目标：1)领导力；2)现场 协调与行政管理；3)通信管理；4)科学监督。 这样创造的研究环境将提供一个特殊的机会，通过重新塑造潜在的 劣势-多个参与机构-转变为显著的优势，即非常广泛和 前列腺癌研究人员的深度联盟，具有良好的承诺历史和 在前列腺癌转移方面的研究成果。

Project Summary - Program Integration and Management This P01 grant application consists of four investigator-initiated and led research projects at geographically distinct locations interacting with two core resources constructed around a theme of prostate cancer metastasis. Our P01 joins multi-disciplinary expertise and state-of-the art research projects with commitments from a leading institution to produce successful advances in our understanding of the drivers of prostate cancer metastasis. The projects and cores proposed in this application are highly integrated and are poised to take maximum advantage of the program project grant mechanism to achieve its overall goals. This multi-center structure is both the greatest strength of this P01 and yet is also a challenge. Administration will be especially important in that it will provide the coordinated management structure, allowing each participating institution to interact and communicate effectively. A flexible, highly interactive administrative structure is proposed whereby research plans can be collaboratively developed and progress can be continuously monitored. The overall objective of Program Integration and Management is to provide leadership, direction, coordination, and administrative services for the purposes of enhancing research productivity and maintaining a highly effective research environment. An important goal will be to foster the exchange of ideas and promote collaboration through interactions between the Project Leaders, Core Directors and all members of the research groups. In order to achieve the overall objective, Program Integration & Management will focus on the following primary objectives: 1) Leadership; 2) Site Coordination & Administrative Management; 3) Communications Management and 4) Scientific Oversight. The research environment so created will provide an exceptional opportunity by recasting a potential weakness- the multiple participating institutions - into a significant strength, namely, a remarkably broad and deep coalition of prostate cancer investigators with a demonstrated history of commitment and accomplishment in the study of prostate cancer metastasis.