Optimizing a dyadic physical activity intervention for Hispanics with osteoarthritis and their physical activity supporter

项目总结/摘要 西班牙裔人不太可能达到身体活动指南，而那些患有骨关节炎的人更有可能报告 更大的关节疼痛，功能限制和工作限制比非西班牙裔白人。在西班牙裔中，社会 文化因素是重要的干预考虑因素，因为相互依存的价值 在传统的西班牙文化中独立。据推测，文化敏感的PA干预措施 为西班牙裔人设计，提供了减少体力活动差异的潜力，因此也减少了OA症状。这 一项研究将调整西班牙裔骨关节炎患者的自我管理6周步行干预，Camine con Gusto（轻松行走），适用于由患有骨关节炎的西班牙裔人及其社交网络成员组成的二人组 谁支持他们的身体活动尝试（“支持者”）。发展一种二元的身体活动干预 由相互依存的文化价值观塑造的将使西班牙裔骨关节炎患者及其支持者参与进来 从而积极地影响彼此的身体活动并提供更大的骨关节炎症状 救灾两个目标将实现拟议研究的总体目标：1）开发四个候选二元 靶向PA和OA症状的组分;和2）使用药物组合物测定组分的初始功效。 随机前后试点研究。在第一个目标下，将制定四个二元干预组成部分， 利益相关者小组的意见和指导小组的指导。五个干预条件将是 测试实施的可接受性和可行性（每种条件N= 10对）。四个条件包括 候选成分之一+ Camine con Gusto，第五个条件将包括所有候选成分 + Camine con Gusto.根据定性和定量评估以及利益攸关方小组 根据反馈意见，将修订四个二元干预组成部分，为目标2做准备。根据第二个 目的：采用随机析因设计确定二元干预的初始疗效 西班牙裔骨关节炎患者的日常步骤。析因设计将引导测试条件 由组分的不同组合组成，当添加到Camine con Gusto中时， 每日步行六周的疗效。这一目标也将允许检查的往复影响 西班牙裔骨关节炎患者和他们的体育活动支持者之间的日常步骤， 二元分析（行为者-伙伴相互依存模式）。拟议的研究将解决以下几个局限性： 以前的干预措施，a）侧重于西班牙裔骨关节炎，和B）检查一系列的二元 这些组件单独使用，以确定在未来试验中应保留的组件。发现将 通过未来的R 01通知随机对照试验，以评价优化的二元干预的有效性 仅包含“活动”组件的软件包。

PROJECT SUMMARY/ABSTRACT Hispanics are less likely to meet physical activity guidelines and those with osteoarthritis are more likely to report greater joint pain, functional limitations, and work limitations than non-Hispanic Whites. Among Hispanics, social and cultural factors are important intervention considerations because of the value placed on interdependence over independence in traditional Hispanic culture. It is hypothesized that culturally sensitive PA interventions designed for Hispanics offer potential to reduce disparities in physical activity and therefore OA symptoms. This study will adapt the self-administered 6-week walking intervention for Hispanics with osteoarthritis, Camine con Gusto (Walk with Ease) for dyads consisting of Hispanics with osteoarthritis and a member of their social network who supports their physical activity attempts (“supporter”). Developing a dyadic physical activity intervention shaped by the cultural value of interdependence will engage Hispanics with osteoarthritis and their supporters equally, thus positively influencing each other’s physical activity and providing greater osteoarthritis symptom relief. Two aims will achieve the overall goals of the proposed study: 1) Develop four candidate dyadic components targeting PA and OA symptoms; and 2) Determine the initial efficacy of the components using a randomized pre-post pilot study. Under the first aim, four dyadic intervention components will be developed with the input from a stakeholder panel and guidance from the mentoring team. Five intervention conditions will be tested for acceptability and feasibility of implementation (N= 10 dyads per condition). Four conditions will include one of the candidate components + Camine con Gusto and the fifth condition will include all candidate components + Camine con Gusto. Based on qualitative and quantitative assessments and stakeholder panel feedback, the four dyadic intervention components will be revised in preparation for Aim 2. Under the second aim, a randomized factorial design will be implemented to determine the initial efficacy of the dyadic intervention components on the daily steps of Hispanics with osteoarthritis. The factorial design will pilot test conditions consisting of different combinations of the components that when added to Camine con Gusto demonstrate initial efficacy in daily steps over six weeks. This aim will also allow for the examination of the reciprocating influences between Hispanics with osteoarthritis and their physical activity supporters on each other’s daily steps using dyadic analysis (actor-partner interdependence model). The proposed study will address several limitations of previous interventions by a) focusing on Hispanics with osteoarthritis, and b) examining an array of dyadic components separately to determine those components that should be retained in a future trial. Findings will inform a randomized controlled trial via a future R01 to evaluate the efficacy of the optimized dyadic intervention package containing only “active” components.