Monitoring and Stabilizing Behavioral Rhythms to Improve Mental Health

翻译后摘要：HealthRhythms公司。 大量证据支持这样的观点，即行为常规（或“社会节奏”）的规律性中断可能导致 精神症状的发作和全面爆发的事件，通过其对内源性昼夜节律的影响，反之亦然 稳定的社交习惯可以防止新的情绪发作。基于我们的信念，监测、评估和 增加行为节律的规律性对于改善心理健康具有广泛的适用性，我们建立了 HealthRhythms，Inc.（www.healthrhythms.com）的目标是利用移动的技术来增加心理健康的层面 照顾所有的医疗保健。我们的产品模式充分利用了智能手机的普遍性和亲密性， 感测行为参数，其表示在用户的自然环境中捕获的24/7基础上的心理健康的关键指标。 环境，而不是零星的，在临床测量的特点精神卫生保健的日期。产品 我们设想最终将有三个支柱：节奏感测、节奏趋势和节奏稳定。中的前两 这些支柱已经开发，我们产品的数千个许可证已经售出。充分发挥两国 迄今为止取得的成就，SBIR第二阶段直接提案在三个方面扩展了我们的工作：1）进一步验证我们现有的 技术，2）开发我们技术的下一阶段，3）扩展和改进我们的预测模型， 展示我们技术的成本效益。具体目标是：目标1：增强我们的节奏趋势 通过对3,000多名患者的数据进行深入检查和分析，我们的产品已经 被部署。目标2：开发我们技术的预期节律稳定支柱。目标3：扩大 包括在我们的预测模型的数据，并证明其实用性。

Abstract: HealthRhythms, Inc. Substantial evidence supports the idea that disruptions in the regularity of behavioral routines (or ‘social rhythms’) can lead to the onset of psychiatric symptoms and full blown episodes via their impact on endogenous circadian rhythms and, conversely that stable social routines protect against new mood episodes. Based on our conviction that monitoring, evaluating, and increasing the regularity of behavioral rhythms has broad applicability for improving mental health, we established HealthRhythms, Inc. (www.healthrhythms.com) with the goal of using mobile technology to add the layer of mental health care to all of healthcare. Our product model capitalizes on the ubiquity and intimacy of smartphones and their capacity to sense parameters of behavior that represent key indicators of mental health on a 24/7 basis captured in the user’s natural environment, opposed to the sporadic, in-clinic measurement that has characterized mental healthcare to date. The product we envision will ultimately have three pillars: Rhythm Sensing, Rhythm Trending, and Rhythm Stabilization. The first two of these pillars have been developed and thousands of licenses for our product have already been sold. Building on our accomplishments to date, this SBIR Phase II Direct proposal extends our work in three ways: 1) further validating our existing technology, 2) developing the next stage of our technology and 3) expanding and improving our prediction models and demonstrating the cost-effectiveness of our technology. The Specific Aims are: Aim 1: Enhance our Rhythm Trending capabilities through intensive examination and analysis of data from the 3,000+ patients with whom our product has already been deployed. Aim 2: Develop the envisioned Rhythm Stabilization pillar of our technology. Aim 3: Expand the nature of the data included in our prediction models and demonstrate their utility.