Monitoring and Stabilizing Behavioral Rhythms to Improve Mental Health

摘要：HealthRhythms, Inc. 大量证据支持这一观点，即行为习惯（或“社会节奏”）的规律性被破坏可能会导致 通过对内源性昼夜节律的影响而导致精神症状的发作和全面发作，反之亦然 稳定的社交习惯可以防止新的情绪发作。基于我们的信念，监控、评估和 增加行为节律的规律性对于改善心理健康具有广泛的适用性，我们确定 HealthRhythms, Inc. (www.healthrhythms.com) 的目标是利用移动技术增加心理健康层面 关心所有的医疗保健。我们的产品模型利用了智能手机的普遍性和亲密性及其能力 代表心理健康关键指标的行为感知参数，以 24/7 为基础，在用户的自然状态中捕获 环境，而不是迄今为止精神保健特征的零星的临床测量。产品 我们设想最终将拥有三个支柱：节奏感知、节奏趋势和节奏稳定。前两个 这些支柱已经开发出来，我们的产品已售出数千个许可证。建立在我们的 迄今为止的成就，该 SBIR 第二阶段直接提案以三种方式扩展了我们的工作：1）进一步验证我们现有的 技术，2）开发我们技术的下一阶段，3）扩展和改进我们的预测模型和 展示我们技术的成本效益。具体目标是： 目标 1：增强我们的节奏趋势 通过对我们的产品已经治疗过的 3,000 名患者的数据进行深入检查和分析来实现 已部署。目标 2：开发我们设想的节律稳定技术支柱。目标 3：扩大 我们的预测模型中包含的数据并证明了它们的实用性。

Abstract: HealthRhythms, Inc. Substantial evidence supports the idea that disruptions in the regularity of behavioral routines (or ‘social rhythms’) can lead to the onset of psychiatric symptoms and full blown episodes via their impact on endogenous circadian rhythms and, conversely that stable social routines protect against new mood episodes. Based on our conviction that monitoring, evaluating, and increasing the regularity of behavioral rhythms has broad applicability for improving mental health, we established HealthRhythms, Inc. (www.healthrhythms.com) with the goal of using mobile technology to add the layer of mental health care to all of healthcare. Our product model capitalizes on the ubiquity and intimacy of smartphones and their capacity to sense parameters of behavior that represent key indicators of mental health on a 24/7 basis captured in the user’s natural environment, opposed to the sporadic, in-clinic measurement that has characterized mental healthcare to date. The product we envision will ultimately have three pillars: Rhythm Sensing, Rhythm Trending, and Rhythm Stabilization. The first two of these pillars have been developed and thousands of licenses for our product have already been sold. Building on our accomplishments to date, this SBIR Phase II Direct proposal extends our work in three ways: 1) further validating our existing technology, 2) developing the next stage of our technology and 3) expanding and improving our prediction models and demonstrating the cost-effectiveness of our technology. The Specific Aims are: Aim 1: Enhance our Rhythm Trending capabilities through intensive examination and analysis of data from the 3,000+ patients with whom our product has already been deployed. Aim 2: Develop the envisioned Rhythm Stabilization pillar of our technology. Aim 3: Expand the nature of the data included in our prediction models and demonstrate their utility.