Implementation and Evaluation of a Screening Tool for Sexual Dysfunction for Pediatric Cancer Survivors
小儿癌症幸存者性功能障碍筛查工具的实施和评估
基本信息
- 批准号:10448895
- 负责人:
- 金额:$ 21.66万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-07-21 至 2027-06-30
- 项目状态:未结题
- 来源:
- 关键词:AddressAdolescent and Young AdultAdoptionAdultAffectAgeArousalAwardCancer SurvivorshipChildChronicClient satisfactionClinicClinicalClinical TrialsColoradoCommunicationDataDetectionDevelopmentDiagnosisDissemination and ImplementationEducational workshopEffectivenessEnsureEnvironmentEvaluationFeedbackFemaleFosteringFutureGoalsHealthHybridsInterventionInterviewKnowledgeLong-Term EffectsLong-Term SurvivorsMalignant Childhood NeoplasmMalignant NeoplasmsMedicalMedical RecordsMental HealthMentorsMentorshipMethodsModificationMulticenter StudiesOncologyOncology GroupOutcomeOutcomes ResearchPainPatient Outcomes AssessmentsPatientsPatternPediatric HematologyPediatric HospitalsPediatric OncologyPersonsPhysiologicalPopulationPragmatic clinical trialProcessProgram DevelopmentProviderQualitative ResearchQuality of CareQuality of lifeQuestionnairesReach Effectiveness Adoption Implementation and MaintenanceReportingResearchResearch DesignResearch MethodologyResearch PersonnelResearch ProposalsResearch TrainingScienceScreening procedureSex FunctioningSexual DysfunctionStandardizationSurveysTestingTimeTrainingTraining SupportTranslational ResearchUnited StatesUniversitiesUniversity resourcesWorkagedcareercareer developmentchildhood cancer survivorcontextual factorsdesigndissemination scienceeffectiveness evaluationeffectiveness implementation studyeffectiveness implementation trialeffectiveness testingexperiencefuture implementationhealth related quality of lifehybrid type 1 designimplementation evaluationimplementation facilitatorsimplementation frameworkimplementation outcomesimplementation scienceimprovedinformantinnovationintervention effectmultidisciplinaryneuro-oncologypatient orientedpatient-clinician communicationpeerpragmatic trialpreferenceprimary outcomeprogramsprospectiverandomized trialrecruitresearch to practiceroutine screeningsatisfactionscreeningsecondary outcomesexskillssocialsocioeconomicssurvivorshiptooltreatment as usual
项目摘要
PROJECT SUMMARY/ABSTRACT
Background: Sexual dysfunction (SD) is estimated to occur in up to 50% of childhood cancer survivors (CCS)
and has important implications for quality of life and mental health. Effective management of SD in AYA-CCS is
substantially limited due to lack of screening and detection of SD in cancer survivorship settings. Adolescent and
young adult-aged CCS (AYA-CCS) may be particularly vulnerable to SD and its under-recognition due to
developmental challenges. This study addresses this critical barrier and serves as the first step in progressing
toward the long-term goal of improving health-related quality of life in AYA CCS through improved screening,
recognition and treatment of SD among CCS. Candidate: The proposed award will enable the candidate, Dr.
Sopfe, to develop the skills necessary to progress toward her career as an independent researcher leading high
quality pragmatic trials. Training: Specifically, Dr. Sopfe will gain experience in Dissemination & Implementation
(D&I) science, pragmatic clinical trials, and mixed methods, which will propel her toward a research career aimed
at developing and disseminating interventions to improve quality of life for CCS. In addition to experiential training
through the research plan, Dr. Sopfe will benefit from a multidisciplinary mentorship team: Primary Mentor, Dr.
Peterson (hybrid trials, qualitative research, patient-reported outcomes); Co-Mentor, Dr. Chow (pediatric cancer
survivorship, clinical trials); and Methods Mentor, Dr. Studts (D&I, mixed methods). Dr. Sopfe’s training plan
includes formal didactic coursework, workshops, and career development programs. Research Plan: This
proposal’s overall objective is to use patient and provider stakeholder input to refine and test an approach to SD
screening for AYA CCS in a clinic setting. Informed by D&I frameworks, this research proposal will used mixed
methods and iterative testing and modification to refine an SD screening approach (Aim 1). This approach will
be then tested in a pilot type 1 hybrid effectiveness-implementation study (Aims 2 and 3), employing mixed
methods to assess patient and provider outcomes. Environment: The environment for this project is exceptional
with a strong academic Section of Pediatric Hematology/Oncology/BMT at the University of Colorado, the
resources of the University of Colorado Adult and Child Consortium for Health Outcomes Research and Delivery
Science (ACCORDS) (D&I Science Program, Qualitative & Mixed Methods Research Core). The clinical trial will
occur through the 1) Children’s Hospital Colorado (CHCO) HOPE Survivorship Program; CHCO Neuro-Oncology
group; and 3) Seattle Children’s Hospital Cancer Survivorship Program. This multiclinic design will ensure
successful recruitment as well as increase generalizability of findings. Impact: The proposed study will serve as
a necessary first step in improving screening, detection, and treatment of SD in AYA-CCS; future work will include
establishing broader effectiveness our screening approach through a multicenter randomized trial, as well as
development, testing, and dissemination of multidisciplinary interventions for SD in this population.
项目总结/文摘
项目成果
期刊论文数量(0)
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{{ truncateString('Jenna Demedis', 18)}}的其他基金
Implementation and Evaluation of a Screening Tool for Sexual Dysfunction for Pediatric Cancer Survivors
小儿癌症幸存者性功能障碍筛查工具的实施和评估
- 批准号:
10669609 - 财政年份:2022
- 资助金额:
$ 21.66万 - 项目类别:
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