Administrative Core

摘要-行政核心 行政核心将协调IPCAVD计划的科学和行政活动， 确保项目和核心一起运作良好。特别是，它将负责管理 计划的财务管理，计划管理，并通过科学的协调项目和核心 会议和通信，以及确保完全遵守财务和监管规定。主要活动 核心小组将监测IPCAVD相对于里程碑的进展情况，并根据 以确保资源得到有效利用。作为具体目标，核心将提供总体 IPCAVD管理、协调和监督项目（目标1），确保及时进行财务核算 和报告（目标2），确保遵守所有机构、州和联邦研究和cGMP指南 (Aim 3）制定和实施IPCAVD的沟通、出版和数据共享计划（目标4），以及 为所有数据分析提供统计支持（目标5）。核心将与一位 外部咨询委员会（EAC），将审查IPCAVD项目和核心的进展情况，并提供投入 来自DAIDS项目团队，为项目的方向提供指导。核心员工是一个高度 经验丰富的综合管理团队，这将使立即启动和快速进展。 这种团队合作将加速实现该计划的目标，从而最大限度地增加机会， 积极影响人类HIV-1疫苗研究。

ABSTRACT- ADMINISTRATIVE CORE The Administrative Core will coordinate the scientific and administrative activities of this IPCAVD Program, ensuring that the Projects and Cores function well together. In particular, it will be responsible for managing the program’s financial management, program management, and coordinating Projects and Cores through scientific meetings and communications, as well as ensuring full financial and regulatory compliance. A primary activity of the Core will be monitoring IPCAVD progress relative to milestones and measuring this progress against available funding to ensure resources are used efficiently. As Specific Aims, the Core will provide overall IPCAVD management, coordination and supervision of the Program (Aim 1), ensure timely financial accounting and reporting (Aim 2), ensure compliance with all institutional, state, and federal research and cGMP guidelines (Aim 3), develop and implement IPCAVD communication, publication, and data sharing plans (Aim 4), and provide statistical support for all data analyses (Aim 5). The Core will coordinate an annual meeting with an External Advisory Committee (EAC) that will review the progress of IPCAVD Projects and Cores, and with input from the DAIDS Program Team, provide guidance for the Program’s direction. Core staff are part of a highly experienced and integrated management team, which will enable immediate start-up and rapid progress. This teamwork will accelerate advancement toward the Program’s goals, thus maximizing the opportunities to positively impact HIV-1 vaccine research in humans.