Advancing Infectious Disease Detection and Response in Viet Nam

推进越南传染病检测和应对

• 批准号: 10449075
• 负责人: Tan Dang
• 金额: --
• 依托单位: GENERAL DEPARTMENT/ PREVENTIVE MEDICINE
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2024-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10449075
• 关键词: Advancing; Infectious; Disease; Detection; Response

PROJECT SUMMARY FOR APPLICATION Since 1998, the General Department of Preventive Medicine (GDPM) and the United States Centers for Disease Control and Prevention (U.S. CDC) have worked closely to strengthen the surveillance capacity in Viet Nam in emerging infectious disease prevention and response, including preparedness for pandemic influenza. In recent years, the GDPM is the focal point for the Viet Nam Ministry of Health to collaborate with other Ministries in Viet Nam, as well as with international agencies as the national focal point for implementation of International Health Regulations and the Global Health Security Agenda. In 2018, with support from the U.S. CDC, the GDPM has implemented Event Based Surveillance (EBS) and has conducted a nationwide survey on the sero-prevalence of hepatitis B and C. The GDPM would like to propose a Project Application for 5 years. The total funding requested for the first year is USD 504,295 with two research proposals that will expand upon EBS implementation and the nationwide survey on sero-prevalence of hepatitis B and C. The first research study on EBS proposes a mixed methods approach to evaluate different implementation interventions (above routine implementation) in order to improve the frequency, timeliness and quality of the reported events. The second research study proposal focuses on identifying the molecular epidemiology of blood-borne Hepatitis viruses in Viet Nam. The research proposals within this application will be coordinated by the GDPM, a specialized department of the Viet Nam Ministry of Health which performs the function of advising and assisting the Minster of Health in exercising State management, and organizing the implementation of law provisions on preventive medicine nationwide. In this capacity, GDPM is pursuing a Project Application with the U.S. CDC that will support this research to: 1) Use lessons learned from the EBS mixed methods evaluation interventions to improve EBS implementation in Viet Nam; and 2) Provide the necessary database for policy making and action plan development on viral hepatitis prevention and control, as well as diagnosis and management of patients in curative facilities. The research will propose a mixed-methods approach EBS evaluation that will be used to assess the effectiveness and impact of the implementation interventions, and to conduct genotyping of HBV and HCV in a subset of specimens to describe the distribution of their genotypes. We will retrospectively collect costs incurred by any organization involved and essential to the rollout.

申请项目总结 自1998年以来，预防医学总局(GDPM)和美国预防医学中心 疾病控制和预防中心(美国疾控中心)密切合作，加强对 越南预防和应对新发传染病，包括为大流行做好准备 流行性感冒。近年来，GDPM是越南卫生部合作的焦点 与越南其他部委以及作为国家协调中心的国际机构合作 国际卫生条例和全球卫生安全议程的执行情况。2018年，随着 在美国疾控中心的支持下，GDPM已经实施了基于事件的监视(EBS)，并进行了 全国范围内乙肝、丙型肝炎血清流行率调查 GDPM希望提出一个为期5年的项目申请。第一次申请的资金总额 每年504,295美元，其中两项研究建议将在EBS实施后扩大和 全国乙型和丙型肝炎血清流行率调查关于EBS的第一项研究提出 采用混合方法评估不同的执行干预措施(高于常规 执行)，以提高报告事件的频率、及时性和质量。这个 第二项研究计划侧重于确定血液传播疾病的分子流行病学。 越南的肝炎病毒。 本申请范围内的研究建议将由GDPM这一专门部门协调 越南卫生部，其职能是向部长提供咨询和协助 在行使国家管理和组织实施卫生方面的法律规定 全国范围内的预防医学。以此身份，GDPM正在向美国申请项目。 CDC将支持这项研究：1)使用从EBS混合方法评估中吸取的经验教训 干预措施，以改善越南的EBS实施情况；和2)提供必要的数据库，以便 病毒性肝炎防治和诊断方面的政策制定和行动计划制定 以及在治疗设施中对患者的管理。 研究将提出一种混合方法的EBS评估方法，用于评估 实施干预措施的有效性和影响，并对乙肝病毒和丙型肝炎病毒进行基因分型 在样本的子集中描述其基因类型的分布。我们将追溯收集 涉及的任何组织所产生的成本，对推广至关重要。