Strengthening Research Administration and Management for Critical HIV Research in Kenya (STRAM-CHR)

加强肯尼亚关键艾滋病毒研究的研究行政和管理 (STRAM-CHR)

• 批准号: 10472812
• 负责人: James Machoki M'Imunya
• 金额: $ 10.15万
• 依托单位: UNIVERSITY OF NAIROBI
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-02 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10472812
• 关键词: AIDS prevention; Administrator; Award; Basic Science; Businesses; Clinical Research; Collaborations; Communication; Country; Development; Ensure; Epidemic; Ethical Review; Evaluation; Extramural Activities; Faculty; Funding; Funding Opportunities; Goals; Grant; Guidelines; HIV; HIV Infections; HIV therapy; Human Resources; Incidence; Infection; Infrastructure; Institution; International; Investments; Kenya; Knowledge; Medical Education; Mentorship; Monitor; Occupational activity of managing finances; Office of Administrative Management; Outcome; Play; Policies; Practice Management; Prevention; Process; Research; Research Activity; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Research Training; Role; Scientist; Strategic Planning; Targeted Research; Technology; Training; Training Programs; Translational Research; United States National Institutes of Health; Universities; Update; Washington; Work; burden of illness; human subject protection; implementation research; improved; innovation; institutional capacity; mortality; next generation; programs; skills; systems research

ABSTRACT Kenya remains one of the countries in the world with high HIV disease burden with approximately 1.6 million Kenyans living with HIV, and 46,000 new infections annually. Though appreciable progress has been made towards epidemic control, impact is patchy: the incidence of new HIV infections, HIV-related mortality, and severe illness remain unacceptably high. More than 75% of financing for HIV prevention and treatment activities is through external donor funds. From the earliest onset of the HIV epidemic, the University of Nairobi has played an important role in the prevention and control of the HIV epidemic through basic, translational, clinical, and implementation research. However, most of the research projects have been led by international collaborators with fewer local faculty and scientists originating high impact HIV-related research. A major barrier has been insufficient human resources with requisite knowledge and skills to support in the application, management and administration of funded research projects and this has contributed significantly to the paucity of locally initiated high impact HIV research. Over the years, the UoN has made efforts to enhance research administration and management leading to the establishment of the Center for Research, Innovation and Grants Advancement (CERIGA). This Center is an outcome of investments by the US National Institutes of Health (NIH) through the International Extramural Associates Development Award (IEARDA) and the Medical education Partnership Initiative (MEPI) is mandated to support researchers at the University of Nairobi throughout the grant management cycle by identifying funding opportunities, supporting researchers through the application process, management during implementation and closeout in compliance with donor requirements. In partnership with the University of Washington (UW), we propose to implement a project entitled “Strengthening Research Administration and Management for Critical HIV Research in Kenya (STRAM-CHR)” aimed at enhancing local capacity for administrative and financial management required for the research infrastructure support functions at the University of Nairobi (UoN) and local partner institutions. Through this project, first, we aim to provide additional and updated knowledge and skills to research administration personnel working at CERIGA, other funded projects within the UoN, the UoN Finance Department and other institutions collaboratively implementing research projects to build their capacity to support investigators and researchers who are conducting critical HIV research. Secondly, we plan to develop key policies and guidelines for Research Administration and Management at the UoN and develop new ones where they do not exist. Thirdly, we aim to review, update and convert existing relevant training programs to e-format with specific focus on: Research administration and management; Research integrity oversight; Ethical review of research; Information and communications technology systems (ICT) for research and Monitoring and Evaluation. These courses will be accessed by the larger team of research administrators within UoN and all its partners. By the end of the three years of this project, we believe that the UoN will have increased capacity to support application and implementation of donor funded projects and CERIGA will emerge as a Center of Excellence in Research Administration and Management supporting several institutions in Kenya and beyond. Page 1 of 77

摘要 肯尼亚仍然是世界上艾滋病毒疾病负担高的国家之一， 肯尼亚艾滋病毒感染者，每年新增46，000例感染者。虽然已经取得了可观的进展 在控制流行病方面，影响是零散的：新的艾滋病毒感染发生率，艾滋病毒相关死亡率， 严重疾病的发病率仍然高得令人无法接受。超过75%的资金用于艾滋病毒预防和治疗 活动是通过外部捐助资金进行的。从艾滋病毒流行病最早开始， 内罗毕在预防和控制艾滋病毒流行方面发挥了重要作用， 翻译、临床和实施研究。然而，大多数研究项目都是由 由国际合作者与较少的当地教师和科学家发起高影响艾滋病毒相关 research.一个主要障碍是缺乏具备必要知识和技能的人力资源， 支持资助研究项目的申请、管理和行政工作， 这在很大程度上导致了当地发起的高影响力艾滋病毒研究的缺乏。多年来，联合国 努力加强研究行政和管理， 研究、创新和赠款促进中心（CERIGA）。该中心是一个结果， 美国国立卫生研究院（NIH）通过国际校外协会进行的投资 发展奖（IERDA）和医学教育合作伙伴计划（MEPI）的任务是 通过确定资金，在整个赠款管理周期中支持内罗毕大学的研究人员 机会，在申请过程中支持研究人员，实施过程中的管理 并按照捐助方的要求进行收尾工作。与华盛顿大学（UW）合作， 我们建议实施一个名为“加强科研行政管理"的项目 肯尼亚关键艾滋病毒研究基金会（STRAM-ESTA），旨在加强地方行政能力， 和财务管理所需的研究基础设施的支持功能在大学 内罗毕办事处和当地伙伴机构。通过这个项目，首先，我们的目标是提供额外的和 为在CERIGA和其他资助项目工作的研究管理人员提供最新的知识和技能 在联合国内部，联合国财务部和其他机构合作开展研究 开展项目，建设他们的能力，以支持正在进行关键艾滋病毒研究的调查人员和研究人员， research.第二，我们计划为研究行政部门制订主要政策和指引， 管理在UoN和开发新的，他们不存在。第三，我们的目标是审查、更新 并将现有的相关培训计划转换为电子格式，具体侧重于： 与管理;研究诚信监督;研究道德审查;信息与传播 信息和通信技术系统（ICT）的研究和监测与评估。这些课程将由 Uo及其所有合作伙伴内部更大的研究管理团队。到三年结束时， 我们相信，通过这个项目，联合国将有更强的能力来支持应用和实施 捐助者资助的项目和CERIGA将成为一个卓越的研究管理中心， 管理支持肯尼亚和其他地区的几个机构。 第1页，共77页