Developmental Research Program

发展研究计划

• 批准号: 10473686
• 负责人: KIRSTEN B. MOYSICH
• 金额: $ 18.32万
• 依托单位: ROSWELL PARK CANCER INSTITUTE CORP
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-18 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10473686
• 关键词: Advocate; Application procedure; Area; Award; Basic Science; Cancer Research Project; Clinical; Clinical Sciences; Collaborations; Critiques; Data; Development; Diagnosis; Disabled Persons; Environment; Epidemiologist; Etiology; Evolution; Extramural Activities; Faculty; Financial Support; Foundations; Funding; Funding Agency; Future; Goals; Grant; Human; Incubated; Incubators; Individual; Infrastructure; Institution; International; Lead; Malignant neoplasm of ovary; Measures; Pathogenesis; Patients; Peer Review Grants; Pilot Projects; Population; Population Research; Population Sciences; Prevention; Principal Investigator; Procedures; Process; Program Research Project Grants; Recommendation; Research; Research Personnel; Research Project Grants; Resources; Running; Scientist; Source; Specimen; Study Section; Supplementation; Testing; Therapeutic; Time; Translational Research; Underrepresented Minority; University of Pittsburgh Cancer Institute; Vertebral column; Woman; Work; anticancer research; base; career; clinical application; flexibility; high reward; high risk; improved; innovation; interest; next generation; patient population; programs; recruit; research and development; standard of care; success; translational cancer research; translational potential; translational research program

Abstract The Developmental Research Program of the Roswell Park Ovarian Cancer SPORE is a platform to support innovative, potentially high-risk/high-reward, investigator-initiated projects with the potential for maturation into translational ovarian cancer research projects that will transition basic and/or population research findings into research focused on human clinical specimens/patient populations. Furthermore, the funds of the Developmental Research Program will be leveraged by encouraging the development of the pilot projects into collaborative, multi-investigator, multi-institutional translational research programs, or as new Individual Research Projects of the Roswell Park Ovarian Cancer SPORE. Therefore, the Developmental Research Program projects are the ultimate measure of the success of a SPORE and form the base for future translational ovarian cancer research at the individual institutions, as they are springboards for the next generation of R01, P01, Consortium, and SPORE grants. The goals of the proposal review process are not only to identify the most exciting projects, but to provide constructive critiques that are of value both for future submission of the projects to extramural funding sources, and for identifying potential collaborators and resources within the Roswell Park Ovarian Cancer SPORE to increase the competitiveness of future applications. Proposals from faculty with established ovarian cancer research programs, or faculty interested in transitioning to translational ovarian cancer research, will be evaluated by a study section identified by the Executive Committee for scientific merit, with recommendations for funding referred to the Internal Advisory Board for award. The unique strengths of the Developmental Research Program lie in its ability to provide significant financial support in a timely manner to high-risk/pilot projects to develop critical preliminary data, provide a flexible mechanism that can respond rapidly to new initiatives or exciting findings through a formal application procedure using the Executive Committee and Internal Advisory Board, or receive even quicker but lesser funds through an ad hoc award from the Discretionary Fund of the Roswell Park Ovarian Cancer SPORE Principal Investigators.

摘要 罗斯威尔公园卵巢癌的发展研究计划孢子是一个平台，以支持 创新的、潜在的高风险/高回报的、由创业者发起的项目，有可能成熟为 转化卵巢癌研究项目，将基础和/或人口研究结果转化为 研究重点是人类临床标本/患者人群。此外，发展基金 研究计划将通过鼓励试点项目发展为合作， 多研究者，多机构的翻译研究计划，或作为新的个人研究项目， 罗斯威尔公园卵巢癌孢子因此，发展研究计划项目是 SPORE成功的最终衡量标准，并为未来的转化卵巢癌研究奠定基础 在各个机构，因为它们是下一代R 01，P01，联盟的跳板， 孢子赠款。提案审查过程的目标不仅是确定最令人兴奋的项目， 提供建设性的批评，这是有价值的，既为未来提交的项目，以校外资助 来源，并在罗斯威尔公园卵巢癌中确定潜在的合作者和资源 提高未来应用的竞争力。从教师的建议，建立卵巢 癌症研究计划，或有兴趣过渡到转化卵巢癌研究的教师，将 由执行委员会确定的一个具有科学价值的研究部门进行评估，并提出建议 提交内部咨询委员会供资。发展的独特优势 研究计划在于它能够及时地向高风险/试点提供重大的财政支持 开发关键的初步数据的项目，提供一个灵活的机制，可以迅速应对新的 通过执行委员会和内部委员会的正式申请程序， 咨询委员会，或通过酌情基金的特别奖励获得更快但更少的资金 罗斯威尔公园卵巢癌SPORE主要研究者