Developmental Research Program

发展研究计划

• 批准号: 10171150
• 负责人: KIRSTEN B. MOYSICH
• 金额: $ 17.87万
• 依托单位: ROSWELL PARK CANCER INSTITUTE CORP
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-18 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10171150
• 关键词: Advocate; Application procedure; Area; Award; Basic Science; Cancer Research Project; Clinical; Clinical Sciences; Collaborations; Critiques; Data; Development; Diagnosis; Disabled Persons; Environment; Epidemiologist; Etiology; Evolution; Extramural Activities; Faculty; Financial Support; Foundations; Funding; Funding Agency; Future; Goals; Grant; Human; Incubated; Incubators; Individual; Infrastructure; Institution; International; Lead; Malignant neoplasm of ovary; Measures; Pathogenesis; Patients; Peer Review Grants; Pilot Projects; Population; Population Research; Population Sciences; Prevention; Principal Investigator; Procedures; Process; Program Research Project Grants; Recommendation; Research; Research Personnel; Research Project Grants; Resources; Running; Scientist; Source; Specimen; Study Section; Supplementation; Testing; Therapeutic; Time; Translational Research; Underrepresented Minority; University of Pittsburgh Cancer Institute; Vertebral column; Woman; Work; anticancer research; base; career; clinical application; flexibility; high reward; high risk; improved; innovation; interest; next generation; patient population; programs; recruit; research and development; standard of care; success; translational cancer research; translational research program

Abstract The Developmental Research Program of the Roswell Park Ovarian Cancer SPORE is a platform to support innovative, potentially high-risk/high-reward, investigator-initiated projects with the potential for maturation into translational ovarian cancer research projects that will transition basic and/or population research findings into research focused on human clinical specimens/patient populations. Furthermore, the funds of the Developmental Research Program will be leveraged by encouraging the development of the pilot projects into collaborative, multi-investigator, multi-institutional translational research programs, or as new Individual Research Projects of the Roswell Park Ovarian Cancer SPORE. Therefore, the Developmental Research Program projects are the ultimate measure of the success of a SPORE and form the base for future translational ovarian cancer research at the individual institutions, as they are springboards for the next generation of R01, P01, Consortium, and SPORE grants. The goals of the proposal review process are not only to identify the most exciting projects, but to provide constructive critiques that are of value both for future submission of the projects to extramural funding sources, and for identifying potential collaborators and resources within the Roswell Park Ovarian Cancer SPORE to increase the competitiveness of future applications. Proposals from faculty with established ovarian cancer research programs, or faculty interested in transitioning to translational ovarian cancer research, will be evaluated by a study section identified by the Executive Committee for scientific merit, with recommendations for funding referred to the Internal Advisory Board for award. The unique strengths of the Developmental Research Program lie in its ability to provide significant financial support in a timely manner to high-risk/pilot projects to develop critical preliminary data, provide a flexible mechanism that can respond rapidly to new initiatives or exciting findings through a formal application procedure using the Executive Committee and Internal Advisory Board, or receive even quicker but lesser funds through an ad hoc award from the Discretionary Fund of the Roswell Park Ovarian Cancer SPORE Principal Investigators.

摘要 罗斯威尔公园卵巢癌孢子开发研究计划是支持的平台 创新的、潜在的高风险/高回报、由调查员发起的项目，有可能成熟为 转化性卵巢癌研究项目，将基础和/或人口研究成果转化为 研究的重点是人类临床标本/患者群体。此外，开发银行的资金 将利用研究计划，鼓励将试点项目发展为合作、 多研究人员、多机构翻译研究计划，或作为新的个人研究项目 罗斯威尔公园的卵巢癌孢子。因此，发展研究计划项目是 孢子成功的最终衡量标准，并为未来转化性卵巢癌研究奠定基础 在个别机构，因为它们是下一代R01、P01、财团和 孢子赠与。提案审查过程的目标不仅是确定最令人兴奋的项目，而且 提供建设性的意见，这些意见对今后向外部资助的项目的提交都有价值 来源，并确定罗斯韦尔公园卵巢癌的潜在合作者和资源 增加孢子未来应用的竞争力。来自已建立卵巢的教职员工的建议 癌症研究项目，或有兴趣过渡到转化性卵巢癌研究的教职员工，将是 由执行委员会确定的研究部门对科学价值进行评价，并提出建议 将资金交给内部咨询委员会进行授标。发展的独特优势 研究计划的关键在于其能够及时向高风险/试点项目提供重要的财务支持 开发关键初步数据的项目，提供可快速响应新的 通过使用执行委员会和内部机制的正式申请程序提出倡议或取得令人兴奋的结果 咨询委员会，或从酌情基金获得更快但更少的资金 罗斯威尔公园卵巢癌孢子首席调查员。