Molecular biophysics predoctoral training at the Ohio State University

项目概要/摘要 俄亥俄州州立大学（OSU）的分子生物物理学培训计划（MBTP）成立于2017年， 分子生物物理学培训和互动的组织原则。OSU是一个综合性的公共土地 格兰特大学是美国最大的大学之一，近20%的学生来自少数民族。OSU 拥有强大的研究团队，吸引了大量分子生物物理学学生，但毕业于 培训和研究社区分散在几个研究生课程，部门， 院校我们在通过共享的分子生物物理学社区建立统一的分子生物物理学社区方面取得了巨大进展， 培养下一代定量生物医学科学家的使命。MBTP带来了不同的群体 一起，创造一个综合的培训经验，其中来自三个不同的研究生课程的学生 （生物物理学，俄亥俄州国家生物化学计划和化学研究生课程）和许多不同的 本科专业的学生相互学习，并从更广泛的导师群体中学习。所有学员获得核心 在大分子和物理生物化学的培训，在生物物理学的基础，并在负责 以最高标准的严谨性和可重复性进行研究。这种广度确保受训者能够 同样好地沟通我们最具挑战性的生物医学问题和现代定量 和分子方法来解决这些问题，同时成为负责任的公民和研究人员。的协调计划 从广泛的选修课程选择，确保学生有足够的深度，成功地在他们的 研究项目。每月一次的系列研讨会和每年一次的专题讨论会为该计划提供了凝聚力， 将独特的培训机会融入职业探索、专业发展、最佳指导 实践，并持续参与道德操守培训。在这里，我们建议深化和扩大这一项目， 吸引了一大批来自医学和工程领域的年轻研究人员作为培训师， 培养一个更大的，但仍然高度多样化的学生群体，提高定量技能的严谨性，并扩大 重点领域包括冷冻EM和生物医学工程。与此同时，培训人员将参与证据- 基于实践来提升他们的指导技能。NIH在该项目中投入的资源将 由机构增强，共同使我们能够招募和留住最强的跨学科学生 更多地纳入代表性不足的群体。卓越、协作和 跨学科，多样性和包容性是用来建立在我们的最高质量的培训原始计划， 为分子生物物理学的学生提供研究和职业发展。

PROJECT SUMMARY/ABSTRACT The Molecular Biophysics Training Program (MBTP) at The Ohio State University (OSU) was formed in 2017 as an organizing principle for training and interaction in molecular biophysics. OSU is a comprehensive public land grant university, one of the largest in the nation, and nearly 20% of its students are from minority groups. OSU has a strong group of researchers and attracts a strong student pool in molecular biophysics, but graduate training and the research community were fragmented over several graduate programs, departments, and colleges. We have made great progress in building a unified molecular biophysics community through a shared mission of training the next generation of quantitative biomedical scientists. MBTP brings disparate groups together and creates an integrated training experience, in which students from three different graduate programs (Biophysics, the Ohio State Biochemistry Program, and the Chemistry Graduate Program) and many different undergraduate majors learn from each other and from a broader group of mentors. All trainees obtain core training in macromolecular and physical biochemistry, in the fundamentals of biophysics, and in the responsible conduct of research with the highest standard of rigor and reproducibility. This breadth ensures that trainees can communicate equally well about our most challenging biomedical problems and about the modern quantitative and molecular methods to address these, while being responsible citizens and researchers. A coordinated plan from a wide selection of elective courses ensures that students have enough depth to be successful in their research projects. A monthly workshop series and a yearly symposium provide cohesion to the program and incorporate unique training opportunities in career exploration, professional development, mentoring best practices, and continuous engagement with ethics training. Here we propose to deepen and expand this project, drawing in a large, diverse community of new young investigators in medicine and engineering as trainers, training a larger though still highly diverse cohort of students, raising the rigor of quantitative skills, and expanding focus areas to include cryo-EM and biomedical engineering. At the same time, trainers will engage in evidence- based practices to elevate their mentoring skills. The resources invested in the program by NIH will be augmented by the institution, together allowing us to recruit and retain the strongest interdisciplinary students with greater inclusion of underrepresented groups. Guiding principles of excellence, collaboration and interdisciplinarity, and diversity and inclusion are used to build on our original plan for the highest quality training, research and career development for students of molecular biophysics.