Deep imaging for understanding molecular processes in complex organisms

深度成像用于了解复杂生物体的分子过程

• 批准号: LE240100091
• 负责人: Prof Elizabeth New
• 金额: $ 66.68万
• 依托单位: The University of Sydney
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE240100091
• 关键词: Deep; imaging; understanding; molecular; processes

This project aims to establish a new fluorescence-based imaging platform that provides an unprecedented combination of sensitivity and spectral discrimination for investigating molecular processes deep within biological tissues. It aims to generate fundamental knowledge in biology, chemistry and materials science relevant to emerging technologies including synthetic tissue construction, nanoparticle assisted delivery of bioactive compounds, molecular sensors, and designer plants. Expected outcomes are high impact discoveries, training opportunities, cross-disciplinary and cross-institutional collaborations and publications addressing fundamental questions that will ultimately contribute to improved crop production and biomedical products.

该项目旨在建立一个新的基于荧光的成像平台，提供前所未有的灵敏度和光谱分辨力的组合，用于研究生物组织深处的分子过程。它旨在产生与新兴技术相关的生物学，化学和材料科学的基础知识，包括合成组织构建，纳米颗粒辅助递送生物活性化合物，分子传感器和设计植物。预期成果是高影响力的发现，培训机会，跨学科和跨机构的合作和出版物，解决最终将有助于改善作物生产和生物医学产品的基本问题。