Integrated Health Sciences Facility Core

综合健康科学设施核心

• 批准号: 10652261
• 负责人: Nirupama Putcha
• 金额: $ 19.87万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-24 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10652261
• 关键词: Address; Advocacy; Advocate; Affect; Animals; Bioinformatics; Biological Specimen Banks; Biometry; Chromium; Communication; Communities; Community Health; Consultations; Core Facility; Data Science; Development Plans; Disease; Ensure; Environmental Exposure; Environmental Hazards; Environmental Health; Environmental Risk Factor; Exposure to; Fostering; Future; Generations; Goals; Health; Health Policy; Health Promotion; Health Sciences; In Vitro; Infrastructure; Institution; Knowledge; Link; Maryland; Mission; Modeling; National Institute of Environmental Health Sciences; Neighborhood Health Center; Outcome; Outcomes Research; Personal Satisfaction; Policies; Population Study; Production; Public Health; Race; Research; Research Design; Research Personnel; Research Project Grants; Resources; Risk; Role; Science; Services; Social Policies; Training; Training and Education; Translating; Translational Research; Translations; Trust; Work; advanced analytics; community based participatory research; community engaged research; community engagement; community organizations; data management; design; experience; faculty community; hazard; human subject; improved; in silico; in vivo; innovation; manufacture; member; multidisciplinary; population health; recruit; sound; translational engagement; translational framework; vulnerable community

ABSTRACT (Integrated Health Sciences Facility Core, IHSFC) The primary mission of the Center for Community Health: Addressing Regional Maryland Environmental Determinants of Disease (CHARMED) is to understand how exposures to environmental factors cause adverse health outcomes and to translate our findings into action to protect and promote the health and well-being of vulnerable communities in the Maryland region. To accomplish this mission, the IHSFC will interact closely with other CHARMED Cores including the Administrative Core (AC), Community Engagement Core (CEC), and the Thematic Research Groups (TRGs), to assist Center members with the design and execution of community- engaged research (CEnR) and co-production of knowledge with community stakeholders. The IHSFC will provide a broad suite of services that will be applied to a CEnR translational framework. To this end, the IHSFC will advance CEnR through fostering and supporting investigator partnerships with community-based organizations, through: Aim 1) assisting them in planning environmental health research; Aim 2) provide them with the necessary resources (expertise, technical) for the execution of scientifically sound, community- responsive research projects; and Aim 3) provide guidance and assistance with effective dissemination and translation of CEnR outcomes and impact to a broad range of stakeholders. These aims will be tightly linked to consultation and other services provided by four interactive teams: 1) Population Health Sciences Team (PHST), 2) Environmental Data Science Team (EDT), 3) Mechanistic Science Team (MST), and 4) Translational Research Team (TST). In close coordination with the CEC and the Executive Committee (EC), the PHST will facilitate stakeholder/investigator team building and creation of inclusive, comprehensive research project plans, that are responsive to the community stakeholder’s needs. The EDT will provide statistical review of study designs and research plans and assist in biostatistical and bioinformatic analyses of results to ensure that all studies are rigorously designed and powered. The MST will provide investigative teams with access to an array of advanced analytical capabilities and infrastructure for the conduct of mechanistic studies needed for basic scientific discovery. The TRT will provide training/education and assistance to Center members and stakeholders in communication and translation of their findings to a broad range of stakeholders in an audience-appropriate manner. The impact of the Center’s research will ideally include but is certainly not limited to an increase in the capacity of CHARMED investigators to conduct translational CEnR research, and to identify the health risks associated with exposures to environmental hazards in the greater Maryland region. Longer term impacts include: 1) changes in community environmental exposures; 2) changes in public health policy; and ultimately in 3) improvements in community health outcomes.

摘要（综合健康科学设施核心，IHSFC） 社区卫生中心的主要任务：针对马里兰州的地区环境 疾病的决定因素（Charmed）是要了解对环境因素的暴露如何导致对手 健康成果，并将我们的发现转化为保护和促进健康和福祉的行动 马里兰州地区的脆弱社区。为了完成这项任务，IHSFC将与 其他迷人的核心，包括行政核心（AC），社区参与核心（CEC）和 主题研究小组（TRG），以协助中心成员的设计和执行社区 - 参与研究（CENR）和与社区利益相关者共同生产知识。 IHSFC会 提供一套广泛的服务，将应用于CENR翻译框架。为此，IHSFC 将通过促进和支持调查员的合作伙伴关系来推进CENR 组织，通过：目标1）协助他们计划环境健康研究；目标2）给他们 凭借必要的资源（专业知识，技术）来执行科学的声音，社区 - 响应式研究项目；目标3）在有效传播和 CENR结果的翻译和对广泛利益相关者的影响。这些目标将紧密相关 四个互动团队提供的咨询和其他服务：1）人口健康科学团队（PHST）， 2）环境数据科学团队（EDT），3）机械科学团队（MST），4）翻译 研究团队（TST）。与CEC和执行委员会（EC）密切协调，PHST将 促进利益相关者/调查员团队建设和创建包容性，全面的研究项目计划， 响应社区利益相关者的需求。 EDT将提供研究统计评论 设计和研究计划，并协助对结果的生物统计和生物信息学分析，以确保所有人 研究经过严格设计和动力。 MST将为调查团队提供访问阵列 基本所需的机械研究的高级分析能力和基础设施 科学发现。 TRT将为中心成员和利益相关者提供培训/教育和协助 在沟通和翻译中，他们的发现与适合观众的广泛利益相关者 方式。理想情况下，该中心研究的影响将包括，但当然不限于增加 诱人的调查人员进行转化CENR研究的能力，并确定健康风险 与大马里兰州地区环境危害的暴露有关。长期影响 包括：1）社区环境暴露的变化； 2）公共卫生政策的变化；最终 在3）改善社区健康成果。