Integrated Health Sciences Facility Core

综合健康科学设施核心

• 批准号: 10652261
• 负责人: Nirupama Putcha
• 金额: $ 19.87万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-24 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10652261
• 关键词: Address; Advocacy; Advocate; Affect; Animals; Bioinformatics; Biological Specimen Banks; Biometry; Chromium; Communication; Communities; Community Health; Consultations; Core Facility; Data Science; Development Plans; Disease; Ensure; Environmental Exposure; Environmental Hazards; Environmental Health; Environmental Risk Factor; Exposure to; Fostering; Future; Generations; Goals; Health; Health Policy; Health Promotion; Health Sciences; In Vitro; Infrastructure; Institution; Knowledge; Link; Maryland; Mission; Modeling; National Institute of Environmental Health Sciences; Neighborhood Health Center; Outcome; Outcomes Research; Personal Satisfaction; Policies; Population Study; Production; Public Health; Race; Research; Research Design; Research Personnel; Research Project Grants; Resources; Risk; Role; Science; Services; Social Policies; Training; Training and Education; Translating; Translational Research; Translations; Trust; Work; advanced analytics; community based participatory research; community engaged research; community engagement; community organizations; data management; design; experience; faculty community; hazard; human subject; improved; in silico; in vivo; innovation; manufacture; member; multidisciplinary; population health; recruit; sound; translational engagement; translational framework; vulnerable community

ABSTRACT (Integrated Health Sciences Facility Core, IHSFC) The primary mission of the Center for Community Health: Addressing Regional Maryland Environmental Determinants of Disease (CHARMED) is to understand how exposures to environmental factors cause adverse health outcomes and to translate our findings into action to protect and promote the health and well-being of vulnerable communities in the Maryland region. To accomplish this mission, the IHSFC will interact closely with other CHARMED Cores including the Administrative Core (AC), Community Engagement Core (CEC), and the Thematic Research Groups (TRGs), to assist Center members with the design and execution of community- engaged research (CEnR) and co-production of knowledge with community stakeholders. The IHSFC will provide a broad suite of services that will be applied to a CEnR translational framework. To this end, the IHSFC will advance CEnR through fostering and supporting investigator partnerships with community-based organizations, through: Aim 1) assisting them in planning environmental health research; Aim 2) provide them with the necessary resources (expertise, technical) for the execution of scientifically sound, community- responsive research projects; and Aim 3) provide guidance and assistance with effective dissemination and translation of CEnR outcomes and impact to a broad range of stakeholders. These aims will be tightly linked to consultation and other services provided by four interactive teams: 1) Population Health Sciences Team (PHST), 2) Environmental Data Science Team (EDT), 3) Mechanistic Science Team (MST), and 4) Translational Research Team (TST). In close coordination with the CEC and the Executive Committee (EC), the PHST will facilitate stakeholder/investigator team building and creation of inclusive, comprehensive research project plans, that are responsive to the community stakeholder’s needs. The EDT will provide statistical review of study designs and research plans and assist in biostatistical and bioinformatic analyses of results to ensure that all studies are rigorously designed and powered. The MST will provide investigative teams with access to an array of advanced analytical capabilities and infrastructure for the conduct of mechanistic studies needed for basic scientific discovery. The TRT will provide training/education and assistance to Center members and stakeholders in communication and translation of their findings to a broad range of stakeholders in an audience-appropriate manner. The impact of the Center’s research will ideally include but is certainly not limited to an increase in the capacity of CHARMED investigators to conduct translational CEnR research, and to identify the health risks associated with exposures to environmental hazards in the greater Maryland region. Longer term impacts include: 1) changes in community environmental exposures; 2) changes in public health policy; and ultimately in 3) improvements in community health outcomes.

综合健康科学设施核心(IHSFC) 社区健康中心的主要任务：解决马里兰地区的环境问题 疾病的决定因素(魔咒)是为了了解暴露在环境因素下是如何导致不利的 并将我们的调查结果转化为保护和促进健康和福祉的行动 马里兰州地区的弱势社区。为了完成这一使命，IHSFC将与 其他迷人核心，包括管理核心(AC)、社区参与核心(CEC)和 主题研究小组(TRGS)，协助中心成员设计和执行社区- 参与研究(Cenr)并与社区利益攸关方共同生产知识。IHSFC将 提供一系列将应用于cenr翻译框架的服务。为此，IHSFC 将通过促进和支持与社区为基础的调查员伙伴关系来促进CENR 各组织，通过以下方式：目标1)协助其规划环境健康研究；目标2)提供 拥有必要的资源(专业知识、技术)，以执行科学合理的、社区- 响应性研究项目；以及目标3)提供指导和援助，有效传播和 将中央审查结果和影响翻译给广泛的利益攸关方。这些目标将紧密联系在一起 由四个互动团队提供咨询和其他服务：1)人口健康科学团队(PHST)， 2)环境数据科学团队(EDT)，3)机械科学团队(MST)，4)翻译 研究团队(TST)。在与CEC和执行委员会(EC)的密切协调下，公共卫生科学委员会将 促进利益相关者/调查员团队建设和创建包容性、综合性的研究项目计划； 响应社区利益相关者的需求。EDT将提供对研究的统计审查 设计和研究计划，并协助对结果进行生物统计和生物信息分析，以确保所有 研究的设计和动力都是严格的。MST将为调查小组提供访问阵列的权限 先进的分析能力和基础设施，用于进行基础设施所需的机械研究 科学发现。TRT将为中心成员和利益攸关方提供培训/教育和援助 在适合受众的情况下与广泛的利益相关者沟通和翻译他们的调查结果 举止。该中心的研究的影响理想地将包括但肯定不限于增加 有魅力的调查人员进行转译中心研究并识别健康风险的能力 与大马里兰州地区的环境危害有关。更长期的影响 包括：1)社区环境暴露的变化；2)公共卫生政策的变化；以及最终 3)改善社区卫生结果。