NRSA Training Core

NRSA 培训核心

• 批准号: 10653273
• 负责人: Joya Chandra
• 金额: $ 80.15万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-24 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10653273
• 关键词: Address; Admission activity; Area; Awareness; Big Data; Biomedical Research; Cancer Center; Clinical Sciences; Competence; Development; Discipline; Doctor of Medicine; Doctor of Philosophy; Entrepreneurship; Environment; Goals; Health Sciences; Individual; Informatics; Knowledge; Leadership; Medical center; Mentors; National Research Service Awards; Performance; Postdoctoral Fellow; Process; Research; Research Training; Resources; Science; Structure; Students; TNFSF15 gene; Texas; Training; Training Programs; Translational Research; Universities; Work; Workforce Development; career; career development; clinical center; doctoral student; faculty mentor; graduate school; health care delivery; interest; pre-doctoral; programs; skills; translational goal; translational pipeline

Contact PD/PI: McPherson, David D. NRSA-Training-001 (011) This TL1 Training Core, a part of Center for Clinical and Translational Sciences (CCTS) CTSA application, will provide 11 predoctoral PhD or MD/PhD students and 4 postdoctoral fellows annually with high-level and effective training in translational science. The major goal of this program is to provide high-level and effective training that promotes leadership in the translational sciences. TL1 trainees complete a competency-based training program that delivers a foundational understanding of the translational sciences as well as training in essential enrichment areas of career and professional development, including team science, leadership, entrepreneurship, and big data informatics/analytics. This training, with support for up to 2 years, promotes leadership in the translational sciences and contributes to workforce development of this field. Predoctoral trainees are appointed from the diverse student body of The University of Texas M. D. Anderson Cancer Center (UT MDACC) UTHealth Graduate School of Biomedical Sciences (UT-GSBS), a graduate school jointly administered and shared by The University of Texas Health Science Center at Houston (UTHSC-H) and UT MDACC. Postdoctoral trainees are appointed from both UTHSC-H and UT MDACC. This unique collaborative training environment is located in the Texas Medical Center, an extensive, world-class concentration of biomedical research and healthcare delivery. UT-GSBS students are admitted through an umbrella program where they receive fundamental knowledge in the biomedical sciences before branching out into discipline- specific programs offering in-depth research training. However, these discipline-specific programs do not provide a structured opportunity for trainees to gain knowledge and enrichment across the spectrum of translational sciences. This TL1 Training Core is focused on addressing this unmet need. Likewise, this program will provide postdoctoral fellows specialized training in translational sciences. TL1 trainees are selected by a competitive process that identifies promising individuals who show serious interest in translational research, have outstanding performance in coursework, and are mentored by faculty fully aware of the translational mission of the TL1 Core. Trainees are required to take courses and participate in enrichment activities that fulfill 11 targeted competencies that prepare them to rapidly integrate their skills into the clinical and translational sciences workforce. Extensive resources in the translational sciences, available through the CCTS, UTHSC-H, UT MDACC, and the Texas Regional CTSA Consortium, allow trainees to formulate personalized training programs that fit their research and career goals. All mentors are required to take Mentoring Works! Training to help align training and career development. Trainees who complete this program will have obtained specific skills to assist them in conducting collaborative science in the translational workforce.

联系PD/PI：McPherson，David D. NRSA-Training-001（011） 这个TL1培训核心是临床和转化科学中心（CCTS）CTSA应用的一部分，将 每年提供11位专业博士学位或医学博士学位/博士学位学生和4名博士后研究员，并提供高级和 有效的翻译科学培训。该计划的主要目标是提供高级有效 培训可以促进转化科学领域的领导。 TL1学员完成了基于能力的 培训计划对转化科学和培训有基本的理解 职业和专业发展的基本丰富领域，包括团队科学，领导力， 企业家精神和大数据信息学/分析。这项培训最多支持2年，促进了 转化科学领域的领导能力，并为该领域的劳动力发展做出了贡献。主肠道 学员是从得克萨斯大学M. D. Anderson Cancer的多元化学生团体任命的 中心（UT MDACC）联合研究生院的Uthealth生物医学科学研究生院（UT-GSB） 由休斯敦（UTHSC-H）和UT的德克萨斯大学健康科学中心管理和共享 MDACC。博士后学员由UTHSC-H和UT MDACC任命。这种独特的合作 培训环境位于德克萨斯医学中心，这是一个广泛的世界一流的集中度 生物医学研究和医疗保健提供。 UT-GSB的学生通过雨伞计划被录取 他们在生物医学科学领域获得基本知识之前，然后将 提供深入研究培训的特定计划。但是，这些纪律特定的程序没有 为学员提供了一个结构化的机会 翻译科学。该TL1训练核心的重点是满足这种未满足的需求。同样，这个 计划将提供翻译科学专业培训的博士后研究员。 TL1学员是 由竞争过程选择，该过程确定有前途的个人，他们对 翻译研究，在课程中表现出色，并受到教师的指导 TL1核心的转化任务。学员必须参加课程并参加 充实的活动达到了11种有针对性的能力，使他们迅速将技能融入到 临床和转化科学劳动力。转化科学的大量资源，可用 通过CCT，UTHSC-H，UT MDACC和德克萨斯州CTSA联盟，允许受训者 制定适合其研究和职业目标的个性化培训计划。所有导师都必须 接受指导作品！培训以帮助调整培训和职业发展。完成此工作的受训者 计划将获得特定的技能，以帮助他们在翻译中进行协作科学 劳动力。

项目成果

Clinical, molecular, metabolic, and immune features associated with oxidative phosphorylation in melanoma brain metastases.

• DOI: 10.1093/noajnl/vdaa177
• 发表时间: 2021-01
• 期刊: Neuro-oncology advances
• 作者: Fischer GM;Guerrieri RA;Hu Q;Joon AY;Kumar S;Haydu LE;McQuade JL;Vashisht Gopal YN;Knighton B;Deng W;Hudgens CW;Lazar AJ;Tetzlaff MT;Davies MA
• 通讯作者: Davies MA

Human Minor Salivary Glands: A Readily Available Source of Salivary Stem/Progenitor Cells for Regenerative Applications.

人类小唾液腺：用于再生应用的唾液干细胞/祖细胞的现成来源。

• DOI: 10.1007/978-1-0716-3609-1_3
• 发表时间: 2024
• 期刊: Methods in molecular biology (Clifton, N.J.)
• 作者: Barrows,CaitlynnML;Wu,Danielle;Young,Simon;Farach-Carson,MaryC
• 通讯作者: Farach-Carson,MaryC

Introduction of Medical Physics Leadership Academy (MPLA) case studies.

• DOI: 10.1002/acm2.13187
• 发表时间: 2021-03
• 期刊: Journal of applied clinical medical physics
• 影响因子: 2.1
• 作者: Gronberg M;Wang D;Medical Physics Leadership Academy (MPLA) Cases Subcommittee, American Association of Physicists in Medicine (AAPM)
• 通讯作者: Medical Physics Leadership Academy (MPLA) Cases Subcommittee, American Association of Physicists in Medicine (AAPM)

Applications of CRISPR Genome Editing to Advance the Next Generation of Adoptive Cell Therapies for Cancer.

• DOI: 10.1158/2159-8290.cd-20-1083
• 发表时间: 2021-03
• 期刊: Cancer discovery
• 影响因子: 28.2
• 作者: Fix SM;Jazaeri AA;Hwu P
• 通讯作者: Hwu P

Statistical process control to monitor use of a web-based autoplanning tool.

• DOI: 10.1002/acm2.13803
• 发表时间: 2022-12
• 期刊: JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS
• 影响因子: 2.1
• 作者: Mehrens, Hunter;Douglas, Raphael;Gronberg, Mary;Nealon, Kelly;Zhang, Joy;Court, Laurence
• 通讯作者: Court, Laurence