Big Data Health Science Scholar Program for Infectious Diseases

传染病大数据健康科学学者计划

• 批准号: 10655607
• 负责人: Neset Hikmet
• 金额: $ 13.83万
• 依托单位: UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-10 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10655607
• 关键词: Academic Training; Active Learning; Age; Area; Artificial Intelligence; Big Data; Biochemistry; Biomedical Engineering; Businesses; COVID-19; Caring; Cessation of life; Chemistry; Clinical Sciences; Communicable Diseases; Competence; Data; Databases; Development; Electronic Health Record; Entrepreneurship; Environment; Faculty; Fostering; Funding; Genomics; Goals; HIV; HIV/AIDS; Health; Health Sciences; Healthcare; Hour; Infectious Diseases Research; Information Technology; Infrastructure; Intelligence; Knowledge; Link; Machine Learning; Manuscripts; Mathematics; Measures; Mentors; Methodology; Mission; National Institute of Allergy and Infectious Disease; Outcome; Patients; Persons; Process; Public Health; Qualifying; Research; Risk; Scholars Program; Schools; Science; Scientist; South Carolina; Strategic Planning; Students; Talents; Technology; Training; Training Programs; Underrepresented Populations; United States; behavioral and social science; big-data science; college; community engagement; comorbidity; data streams; disease transmission; doctoral student; experience; faculty mentor; genomic data; hands on research; health data; health science research; improved; innovation; insight; interest; mobile computing; nanomaterials; next generation; pre-doctoral; programs; recruit; social media; statistics; summer research; training opportunity; wearable device

Abstract Today, a critical mass of previously collected linked health care data is now available for optimizing patient health outcomes. Information, insights, and intelligence existing in such health care data can be unlocked efficiently using Big Data Science (BDS).As people age and live longer, increased demand for care will be two-fold, one for those living with more comorbidities, and second the emergent risks from new infectious diseases like COVID-19.The recent NIAID strategic plan for COVID-19 highlights the urgent and important need for high-quality scientific research to improve knowledge around disease transmission, surveillance, and its impact on health outcomes, and to develop both biomedical and public health measures to mitigate illness and death. The existence of several massive, and information rich big data streams in healthcare (e.g., electronic health records [EHR], mobile technologies, wearable devices, genomic data, geospatial data etc.) and the advances in information and computational technologies (e.g., machine learning and artificial intelligence) now offer an excellent hands-on training opportunity for applying innovative Big Data science (BDS) research to infectious diseases such as HIV/AIDS and COVID-19. To cultivate a thriving and talented pipeline of next generation scientists, it is essential to engage current students early and provide new and innovative training opportunities to generate interest in the biomedical, social, and behavioral, and clinical sciences. Therefore, we propose offering a 10-week Short-Term Summer Research Training Program titled “Big Data Health Science Scholar Program for Infectious Diseases” targeted towards predoctoral students in physical and/or quantitative sciences (departments of biomedical engineering, integrated information technology, chemistry/biochemistry, mathematics, statistics etc.) from across South Carolina (SC) and the United States (US). Predoctoral students completing this training will engage in experiential learning through hands- on research in infectious disease areas like HIV/AIDS, and COVID-19, both relevant to the NIAID mission. Selected predoctoral students will be paired with Program Faculty mentors from a pool of distinguished participating faculty for one-on-one mentoring. Trainees will be chosen through a competitive process based on their proposed research plan and goals for the summer experience. Specifically, we plan to recruit 8 predoctoral students from physical and quantitative sciences across the US per year (a total of 40 over the entire funding period) to participate in the 10-week summer intensive training program with the following objectives: Objective 1: Create a summer big data science training pipeline for qualified predoctoral students by exposing them to relevant courses/training for competency development in the application of BDS to infectious disease research. Objective 2: Engage trainees in hands-on research using HIV and COVID-19 data. Objective 3: Provide trainees with rich research mentoring experience in BDS research and professional development for at least one year (summer included). The proposed training program will be implemented with support of the existing infrastructure of USC's Big Data Health Center (BDHSC). The BDHSC, one of the USC's Excellence initiatives, promotes and supports Big Data health science research at USC and across SC through capacity development, academic training, professional development, community engagement, and methodological advancement. BDHSC contains 5 content cores (EHR, geospatial, genomic, social media, and bio-nanomaterial) and two supporting hubs (business/entrepreneurship and technology) with the involvement of 43 faculty from 10 USC college/schools. Upon the completion of the proposed training, each trainee is expected to: 1) complete 12 hours of academic training; 2) obtain hands-on BDS experience working on NIAID-funded research databases; and 3) develop at least one BDS manuscript on HIV or COVID-19 with their Program Faculty mentor. The training program will foster the research environment to encourage diverse applicants, including those from underrepresented groups, to pursue further Big Data health science research in HIV, COVID-19 and other NIAID focus areas.

摘要 今天，以前收集的大量相关医疗保健数据现在可用于 优化患者健康结果。信息、洞察力和智慧存在于这样的健康 使用大数据科学（BDS）可以有效地解锁护理数据。随着人们年龄的增长和生活的改善， 更长的时间，对护理的需求将增加两倍，一个是那些患有更多合并症的人， 其次是新冠肺炎等新型传染病的紧急风险。 COVID-19战略计划强调了对高质量科学研究的迫切和重要需求 开展研究，以提高对疾病传播、监测及其对 卫生成果，并制定生物医学和公共卫生措施，以减轻疾病 与死存在多个海量且信息丰富的大数据流， 医疗保健（例如，电子健康记录[EHR]，移动的技术，可穿戴设备， 基因组数据、地理空间数据等）以及信息和计算技术的进步 技术（例如，机器学习和人工智能）现在提供了一个很好的动手 将创新的大数据科学（BDS）研究应用于传染病的培训机会 艾滋病和COVID-19等疾病。培养一个蓬勃发展的人才管道， 因此，有必要尽早让现有的学生参与进来，并提供新的和 创新的培训机会，以产生对生物医学，社会和行为的兴趣， 和临床科学。因此，我们建议提供为期10周的短期夏季研究 培训计划名为“传染病大数据健康科学学者计划” 针对物理和/或定量科学的博士前学生（ 生物医学工程，综合信息技术，化学/生物化学， 数学、统计学等）从横跨南卡罗来纳州（SC）和美国（US）。 完成这项培训的博士前学生将通过动手进行体验式学习- 艾滋病毒/艾滋病和COVID-19等传染病领域的研究，两者都与 NIAID使命。选定的博士前学生将与计划教师导师配对， 一个杰出的参与教师一对一的指导池。学员将被选中 根据他们提出的夏季研究计划和目标， 体验.具体而言，我们计划从物理和定量方面招收8名博士生 美国各地的科学每年（在整个资助期间共40）参加 为期10周的暑期强化培训计划，目标如下： 目标1：为合格的博士预科生创建夏季大数据科学培训管道 学生，让他们参加有关的课程/培训， BDS在传染病研究中的应用。 目标2：让学员参与使用艾滋病毒和COVID-19数据的实践研究。 目标3：为学员提供丰富的BDS研究指导经验， 专业发展至少一年（包括夏季）。拟议的培训 该计划将在南加州大学大数据健康现有基础设施的支持下实施 中心（BDHSC）。BDHSC是南加州大学的卓越计划之一， 通过能力发展，在南加州大学和整个南加州大学进行大数据健康科学研究， 学术培训，专业发展，社区参与和方法 进步。BDHSC包含5个内容核心（EHR、地理空间、基因组、社交媒体和 生物纳米材料）和两个支持中心（商业/创业和技术）， 来自10所南加州大学学院/学校的43名教师参与。在完成拟议的 培训，每位学员预计：1）完成12小时的学术培训; 2）获得 在NIAID资助的研究数据库上工作的实践BDS经验;以及3）在 至少有一份关于艾滋病毒或COVID-19的BDS手稿与他们的计划教师导师。培训 该计划将促进研究环境，以鼓励不同的申请人，包括那些 从代表性不足的群体中，进一步开展艾滋病毒的大数据健康科学研究， COVID-19和其他NIAID重点领域。