Negative symptom formation in schizophrenia: An electrophysiological, neurophysiological and computational modelling investigation
Negative symptom formation in schizophrenia: An electrophysiological, neurophysiological and computational modelling investigation
批准号:
nhmrc : 1090716
负责人:
金额:
$26.11万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Early Career Fellowships
财政年份:
2015
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2015-01-01 至 2018-12-31
中文摘要
精神分裂症的阴性和认知症状被认为与更广泛认可的阳性症状如幻觉和妄想一样致残。最近有人提出,精神分裂症的阴性症状可能是由奖励和惩罚的学习改变引起的。该项目将研究精神分裂症患者在基于奖励和惩罚的学习任务中的大脑活动,同时应用计算建模。
英文摘要
The Negative and cognitive symptoms of schizophrenia have been recognised as being just as disabling as the more widely recognised positive symptoms such as hallucinations and delusions. Recently it has been proposed that negative symptoms in schizophrenia might be caused by alterations in learning from rewards and punishments. This project will investigate brain activity in people with schizophrenia during reward and punishment based learning tasks while applying computational modelling.
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