Training Program in Metabolic Biology

项目摘要/摘要 加州大学伯克利分校/加州大学旧金山分校代谢生物学联合培训计划(TPMB)为 培训学员在严谨、可重复的科学方面打下坚实的基础，并获得专业技能 和知识，以支持未来人类代谢健康和疾病研究领域的领导者。已建成 围绕一个跨部门、跨机构的培训计划，它汇集了世界领先的研究人员 和来自UCB营养科学和毒理学(NST)和加州大学旧金山分校的糖尿病的导师 中心(DC)为博士前研究员提供无与伦比的培训体验。TPMB寻求吸引 来自不同学术背景的高素质学生群体，包括生物化学、细胞和 分子生物学、营养学和生理学。我们的课程是围绕学术的发展和 具备研究、教学和专业服务方面的技能，目标是建立早期研究 独立性和奠定了研究诚信和责任感的基础。除了服用TPMB外 强调代谢调节、研究设计中的人类健康和疾病主题的特定课程 和重复性，数据分析和解释，以及道德行为，学生将能够轮流 通过加州大学伯纳苏斯分校和加州大学帕纳苏斯分校的实验室在第一年进行。TPMB学生将 体验一个滋养人的、多样化的、令人兴奋的环境，这个环境已经建立了一个完善和整合的 两个校区的计划领导层、研究人员和教官社区，并很清楚 这种方法带来的机遇和潜在的挑战。为了做出明智的选择，他们的 轮流入学的学生将在项目中接触到各种以新陈代谢为中心的研究 通过所有TPMB教职员工的入门讲座和参加计划的联合年度务虚会 提供演讲、海报以及与教职员工、学生和博士后的社交互动。TPMB的核心优势 我们的教师素质和呼吸是人类健康和新陈代谢的重点研究课题吗？ 从摄食行为的中枢调控到脂肪细胞生物学和B细胞及其最新技术 从单细胞测序到代谢组学、遗传学、干细胞生物学和生物工程的方法 以及在临床和临床前环境中进行研究的能力。这一广泛的专业知识和 培养协作科学的方法，并为TPMB学生成功过渡到 在学术界、工业界和政府中从事独立的职业，以解决对 NIDDK和改善人类健康和福祉。

Project Summary/Abstract The UC Berkeley/UCSF joint Training Program in Metabolic Biology (TPMB) offers unique opportunities for trainees to gain a strong foundation in rigorous, reproducible science, and to acquire the professional skills and knowledge to support future leaders in the field of human metabolic health and disease research. Built around an inter-departmental, trans-institutional training program, it brings together world-leading researchers and mentors from UCB's Department of Nutritional Sciences and Toxicology (NST) and UCSF's Diabetes Center (DC) to offer an unparalleled training experience for predoctoral fellows. TPMB seeks to attract a diverse group of highly qualified students from various academic backgrounds including biochemistry, cell and molecular biology, nutrition, and physiology. Our curriculum is build around development of scholarship and skills in research, teaching and professional service with the goals of establishing early research independence and laying a foundation for research integrity and responsibility. In addition to taking TPMB specific courses that emphasize human health and disease topics in metabolic regulation, research design and reproducibility, data analysis and interpretation, as well as ethical conduct, students will be able to rotate through laboratories both on the UCB and UCSF Parnassus campuses in their first year. TPMB students will experience a nurturing, diverse, and exciting environment that has build a well-established and integrated community of program leadership, researchers and preceptors across the two campuses and is well aware of the opportunities and potential challenges this approach offers. In order to make informed choices for their rotations incoming students will be exposed to the variety of metabolism centered research in the program through introductory lectures given by all TPMB faculty and participate in the programs joint annual retreat offering talks, posters, and social interactions with faculty, students, and postdocs. A central strength of TPMB is the quality of our faculty and the breath of human health and metabolism focused research topics ranging from central regulation of feeding behavior to adipocyte biology and ß-cells and state-of-the-art technical approaches from single-cell-sequencing, to metabolomics, genetics, stem cell biology, and bioengineering and the ability to pursue research in both clinical and preclinical settings. This wide range of expertise and approaches foster collaborative science and prepare TPMB students to successfully transition into independent careers in academia, industry, and government to tackle problems central to the mission of NIDDK and to improve human health and wellbeing.