Research and Methods Core

我们提议的社区推动的预防肥胖相关癌症研究中心（中心）内的研究和方法核心将为所有核心主任，项目负责人，参与职业提升核心的受训人员以及发展核心的获奖者提供全面，多边的研究和评估资源。服务将包括假设细化，临床和基础科学实验的设计，数据采集和管理，创新和最先进的统计方法的开发和应用，生物统计和地理空间分析，数据解释，以及通过摘要，论文和演示出版中心产生的结果。我们将与所有项目和核心合作，执行所需的定量和定性分析，归档数据集 和分析脚本，以确保分析的再现性，并确保所有结果的正确解释。 我们会在所有研究和试验计划中，采用一致的设计， 与持续贫穷普查区研究有关的背景和成果措施。我们的研究 核心团队参与每个研究项目的开发，适当设计研究 以实现既定的科学目标。我们将定期与项目负责人会面，讨论每个项目的数据处理和分析需求。该核心的成员在管理和集成标准和创新数据类型方面经验丰富，可确保一致和兼容的数据处理。通过为每个项目中的数据分析活动提供研究专业知识和后勤支持，研究和方法核心将有助于专业，道德，高效和严格地使用每个项目生成的数据。

The Research and Methods Core within our proposed Center for Transformative Community-driven Research to Prevent Obesity-related Cancer (the Center) will serve as a comprehensive, multilateral research and evaluation resource to all core directors, project leaders, trainees engaged in the Career Enhancement Core, and awardees of the Developmental Core. Services will include hypothesis refinement, design of clinical and basic science experiments, data acquisition and management, development and application of innovative and state-of-the-art statistical methodology, biostatistical and geospatial analyses, data interpretation, and publication of results generated by the Center through abstracts, papers, and presentations. We will work with all projects and cores in performing the required quantitative and qualitative analyses, archiving data sets and analysis scripts to ensure the reproducibility of analyses and ensure proper interpretation of all results. We will identify and incorporate into all the research and pilot projects the adoption of consistent design(s), contextual and outcome measures relevant to the research in persistent poverty census tracts. Our Research and Methods Core team participated in the development of each research project, properly designing studies to achieve the stated scientific aims. We will meet regularly with project leaders to discuss each project's data processing and analysis needs. The members of this Core are experienced in managing and integrating standard and innovative data types that ensure consistent and compatible data handling. By providing research expertise and logistic support to data analytic activities within each project, the Research and Methods Core will contribute to the professional, ethical, efficient, and rigorous use of the data generated by each project.