Research and Methods Core

我们提议的“社区驱动的变革研究预防肥胖相关癌症中心”（中心）的研究和方法核心将为所有核心主任、项目负责人、参与职业提升核心的学员和发展核心的获奖者提供全面的多边研究和评估资源。服务将包括假设完善、临床和基础科学实验设计、数据采集和管理、创新和最先进统计方法的开发和应用、生物统计和地理空间分析、数据解释，以及通过摘要、论文和演示发表中心产生的结果。我们将与所有项目和核心合作，执行所需的定量和定性分析，存档数据集

The Research and Methods Core within our proposed Center for Transformative Community-driven Research to Prevent Obesity-related Cancer (the Center) will serve as a comprehensive, multilateral research and evaluation resource to all core directors, project leaders, trainees engaged in the Career Enhancement Core, and awardees of the Developmental Core. Services will include hypothesis refinement, design of clinical and basic science experiments, data acquisition and management, development and application of innovative and state-of-the-art statistical methodology, biostatistical and geospatial analyses, data interpretation, and publication of results generated by the Center through abstracts, papers, and presentations. We will work with all projects and cores in performing the required quantitative and qualitative analyses, archiving data sets and analysis scripts to ensure the reproducibility of analyses and ensure proper interpretation of all results. We will identify and incorporate into all the research and pilot projects the adoption of consistent design(s), contextual and outcome measures relevant to the research in persistent poverty census tracts. Our Research and Methods Core team participated in the development of each research project, properly designing studies to achieve the stated scientific aims. We will meet regularly with project leaders to discuss each project's data processing and analysis needs. The members of this Core are experienced in managing and integrating standard and innovative data types that ensure consistent and compatible data handling. By providing research expertise and logistic support to data analytic activities within each project, the Research and Methods Core will contribute to the professional, ethical, efficient, and rigorous use of the data generated by each project.