Research and Methods Core

研究和方法核心：项目总结 研究和方法核心(RMC)将推动创新方法解决方案的应用 在活人中实施预防癌症的循证干预的挑战 长期处于贫困之中。中心目标是通过公平执行来实现覆盖范围，以满足需求 以及为长期贫困地区的青年、家庭和个人提供服务的服务系统的资源。这个 RMC将通过三个具体目标支持“HOPE&CAIRHE 2gether”(HC2)的研究活动： 目标1：创新：作为促进癌症预防的跨项目方法协同作用的枢纽 持续贫困地区的实施科学。RMC将确保正确应用新颖的 实施研究工具，同时强调由HC2的S推动的独特方法进步 协作结构。这一目标的核心是由RMC公司开发的三种方法促进的创新。 Lead Smith：(1)实施研究逻辑模型；(2)实施结果公共数据 要素工具；和(3)新的和严格的系统，用于纵向跟踪执行战略和 它们随时间的动态变化。目标2：支持：确保对二氯甲烷研究提供方法学支持 活动。RMC将确保HC2的S研究和试点项目获得良好的方法学支持 落实他们的具体目标和HC2的总体目标。具体地说，RMC将识别公共数据 要素，协调共享措施的使用，并提供严格的定量、定性、健康 研究和试点项目中的经济分析和实施科学方法。我们将使用 定量、定性和混合方法，以回答每个项目所述的特定目标以及 通过S的工作，出现了新颖而收敛的研究问题。目标3：评估：测量HC2 研究生产力和影响力。RMC将与管理核心合作，以衡量和 评估S在实现研究和培训里程碑和成果方面取得的进展。我们将使用 翻译科学收益模型，展示我们在现实世界中的工作对指标的影响 HC2和持久贫困倡议的突出特点(RFA-CA-22-015)。 RMC由在预防实施科学方面具有互补专业知识的专家共同领导 方法、研究设计、定量、定性和混合分析方法。四个工作组将 落实RMC的目标：(1)实施评估和测量；(2)生物统计学和研究设计；(3) 定性和混合方法；(4)卫生经济学。RMC将与管理核心协调， 职业提升核心和社区参与团队，以确保方法支持和严谨 跨HC2活动。RMC的贡献将产生关键的方法学进步，以减少 生活在持续贫困中的个人所经历的癌症死亡率差异。

RESEARCH AND METHODS CORE: PROJECT SUMMARY The Research and Methods Core (RMC) will drive the application of innovative methodologic solutions to the challenges of implementing evidence-based interventions for the prevention of cancer among people living in persistent poverty. The central goal is achieving reach through equitable implementation to meet the needs and resources of delivery systems that serve youth, families, and individuals in areas of persistent poverty. The RMC will support the research activities of “HOPE & CAIRHE 2gether” (HC2) through three specific aims: Aim 1: INNOVATE: Serve as a hub for cross-project methodologic synergies to advance cancer prevention implementation science in persistent poverty areas. The RMC will ensure proper application of novel implementation research tools while highlighting unique methodologic advancements facilitated by HC2's collaborative structure. Central to this aim are innovations facilitated by three methods developed by RMC Co- Lead Smith: (1) the Implementation Research Logic Model; (2) an implementation outcomes common data elements tool; and (3) a novel and rigorous system for longitudinal tracking of implementation strategies and their dynamic modifications over time. Aim 2: SUPPORT: Ensure methodologic support for HC2 research activities. The RMC will ensure that HC2's Research and Pilot Projects have excellent methodologic support to carry out their specific aims and those of HC2 overall. Specifically, the RMC will identify common data elements, orchestrate the use of shared measures, and provide rigorous quantitative, qualitative, health economic analyses and implementation science methods across the Research and Pilot Projects. We will use quantitative, qualitative, and mixed methods approaches to answer each project's stated specific aims as well as novel and convergent research questions that emerge through HC2's work. Aim 3: EVALUATE: Measure HC2 research productivity and impact. The RMC will collaborate with the Administrative Core to measure and evaluate HC2's progress toward achieving research and training milestones and outcomes. We will use the Translational Science Benefits Model to demonstrate the impact of our work in the real world on metrics salient to HC2 and the Persistent Poverty Initiative (RFA-CA-22-015). The RMC is Co-Led by experts with complementary expertise in prevention implementation science methods, research design, and quantitative, qualitative, and mixed methods analysis. Four workgroups will carry out RMC's aims: (1) Implementation Evaluation & Measurement; (2) Biostatistics & Research Design; (3) Qualitative & Mixed Methods; and (4) Health Economics. RMC will coordinate with the Administrative Core, Career Enhancement Core, and Community Engagement Team to ensure methodologic support and rigor across HC2 activities. RMC's contributions will generate critical methodologic advances towards reducing the cancer mortality disparities experienced by individuals living in persistent poverty.