Research and Methods Core

研究和方法核心

• 批准号: 10661439
• 负责人: JUSTIN D SMITH
• 金额: $ 27.55万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-03 至 2028-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10661439
• 关键词: Address; Adoption; Advanced Malignant Neoplasm; Area; Behavior; Biometry; Cancer Control; Cancer Prevention Intervention; Child; Collaborations; Common Data Element; Community Services; Ensure; Environmental Exposure; Equity; Evidence based intervention; Family; Fostering; Goals; Health; Individual; Inequity; Infrastructure; Intervention; Knowledge; Leadership; Logic; Malignant Neoplasms; Measurement; Measures; Methodology; Methods; Modeling; Modification; Outcome; Persons; Pilot Projects; Policies; Population; Poverty; Poverty Areas; Prevention; Prevention program; Productivity; Reproducibility; Research; Research Activity; Research Design; Research Methodology; Research Project Grants; Research Project Summaries; Research Support; Resources; Science; Specific qualifier value; Structure; System; Techniques; Time; Training; Translational Research; Underserved Population; United States National Institutes of Health; Work; Youth; cancer prevention; career; community engagement; data sharing; economic evaluation; evaluation/testing; evidence base; experience; health care service; health economics; health equity; implementation evaluation; implementation facilitation; implementation outcomes; implementation process; implementation research; implementation science; implementation strategy; improved; individualized prevention; innovation; mortality disparity; novel; prevent; scale up; synergism; tool

RESEARCH AND METHODS CORE: PROJECT SUMMARY The Research and Methods Core (RMC) will drive the application of innovative methodologic solutions to the challenges of implementing evidence-based interventions for the prevention of cancer among people living in persistent poverty. The central goal is achieving reach through equitable implementation to meet the needs and resources of delivery systems that serve youth, families, and individuals in areas of persistent poverty. The RMC will support the research activities of “HOPE & CAIRHE 2gether” (HC2) through three specific aims: Aim 1: INNOVATE: Serve as a hub for cross-project methodologic synergies to advance cancer prevention implementation science in persistent poverty areas. The RMC will ensure proper application of novel implementation research tools while highlighting unique methodologic advancements facilitated by HC2's collaborative structure. Central to this aim are innovations facilitated by three methods developed by RMC Co- Lead Smith: (1) the Implementation Research Logic Model; (2) an implementation outcomes common data elements tool; and (3) a novel and rigorous system for longitudinal tracking of implementation strategies and their dynamic modifications over time. Aim 2: SUPPORT: Ensure methodologic support for HC2 research activities. The RMC will ensure that HC2's Research and Pilot Projects have excellent methodologic support to carry out their specific aims and those of HC2 overall. Specifically, the RMC will identify common data elements, orchestrate the use of shared measures, and provide rigorous quantitative, qualitative, health economic analyses and implementation science methods across the Research and Pilot Projects. We will use quantitative, qualitative, and mixed methods approaches to answer each project's stated specific aims as well as novel and convergent research questions that emerge through HC2's work. Aim 3: EVALUATE: Measure HC2 research productivity and impact. The RMC will collaborate with the Administrative Core to measure and evaluate HC2's progress toward achieving research and training milestones and outcomes. We will use the Translational Science Benefits Model to demonstrate the impact of our work in the real world on metrics salient to HC2 and the Persistent Poverty Initiative (RFA-CA-22-015). The RMC is Co-Led by experts with complementary expertise in prevention implementation science methods, research design, and quantitative, qualitative, and mixed methods analysis. Four workgroups will carry out RMC's aims: (1) Implementation Evaluation & Measurement; (2) Biostatistics & Research Design; (3) Qualitative & Mixed Methods; and (4) Health Economics. RMC will coordinate with the Administrative Core, Career Enhancement Core, and Community Engagement Team to ensure methodologic support and rigor across HC2 activities. RMC's contributions will generate critical methodologic advances towards reducing the cancer mortality disparities experienced by individuals living in persistent poverty.

研究和方法核心：项目摘要 研究和方法核心（RMC）将推动创新方法解决方案的应用， 实施循证干预措施以预防生活中的癌症的挑战 持续的贫困。中心目标是通过公平实施实现覆盖，以满足需求 以及为持续贫困地区的青年、家庭和个人服务的交付系统的资源。的 RMC将通过三个具体目标支持“HOPE & CAIRHE 2gether”（HC 2）的研究活动： 目标1：创新：作为跨项目方法协同作用的中心，以推进癌症预防 在持续贫困地区实施科学。RMC将确保正确应用新的 实施研究工具，同时强调独特的方法学进步促进HC 2的 协作结构。这一目标的核心是由RMC公司开发的三种方法促进的创新， Lead Smith：（1）实施研究逻辑模型;（2）实施结果通用数据 要素工具;以及（3）用于纵向跟踪实施战略的新颖而严格的系统， 随着时间的推移，它们的动态变化。目标2：支持：确保HC 2研究的方法支持 活动RMC将确保HC 2的研究和试点项目有良好的方法支持， 实现其具体目标和HC 2的总体目标。具体而言，RMC将确定通用数据 元素，协调使用共享的措施，并提供严格的定量，定性，健康， 在研究和试点项目中进行经济分析和实施科学方法。我们将使用 定量、定性和混合方法来回答每个项目所陈述的具体目标以及 通过HC 2的工作出现的新颖和收敛的研究问题。目标3：测量：测量HC 2 研究生产力和影响力。RMC将与行政核心合作， 评估HC 2在实现研究和培训里程碑和成果方面的进展。我们将使用 转化科学效益模型，用于展示我们在真实的世界中的工作对指标的影响 对HC 2和持续贫困倡议（RFA-CA-22-015）具有突出意义。 RMC由在预防实施科学方面具有互补专长的专家共同领导 方法，研究设计，定量，定性和混合方法分析。四个工作组将 实现RMC的目标：（1）实施评估和测量;（2）生物统计学和研究设计;（3） 定性和混合方法;（4）卫生经济学。RMC将与行政核心协调， 职业提升核心和社区参与团队，以确保方法上的支持和严谨性 在HC 2活动中。RMC的贡献将产生关键的方法学进步， 生活在持续贫困中的个人经历的癌症死亡率差异。