Research Training in Sensorimotor Neurorehabilitation

项目摘要 这项建议的目标是在感觉运动神经康复方面实施一种新的研究训练 该计划旨在培养下一代科学家，以满足对神经科学日益增长的需求- 基于康复解决方案。西北大学在运动研究方面有着悠久的、公认的历史 控制、运动残疾和康复以及神经重组；以及在培训下一代 运动和康复科学家(MRS)通过西北大学跨系 自2009年以来，神经科学计划(NUIN)博士计划取得了成功，其成果体现在 20名毕业生目前在学术界和工业界领导着成功的研究生涯。拟议中的计划 建立在这项研究和培训记录的基础上，以培养具有临床和生活/应用能力的学生为使命 有科学背景和具有临床背景的博士后将成为康复科学家 基础、转化性或临床研究。这些科学家将有能力整合来自 涉及感觉运动神经康复的多个学科，包括神经科学、工程学和 临床科学。培训计划将侧重于四个培训目标：1)为 感觉运动功能和控制的基本神经生物学，包括动物之间洞察力的翻译 和人体研究模型；2)学习测量的基本工程实验方法 以及神经和肌肉骨骼感觉和运动功能的分析；3)促进知识共享 在博士后和博士后之间运动障碍患者的临床管理中 学员；及4)提供专业发展训练，以支援日后的康复研究工作 成功。该计划的独特结构是对具有临床专业知识的博士后实习生进行夫妇培训 博士前实习生专注于神经科学。该项目是同类项目中第一个提供博士后 物理治疗医生的研究培训(DPT)，这是一个尚未开发的潜在科学家队列，具有 出现在以科学为基础的医学和循证实践的当代时代。这些DPT 博士后名额的候选人将从研究密集的物理治疗项目中挑选出来 美国。博士前实习生将从NUIN-MRS计划中抽出。翻译型 该计划的跨学科性质将允许临床研究人员与基础和 应用科学研究人员，为翻译研究培训提供了独特的机会。我们打算 为总共12名博士后实习生和5名博士后实习生提供最多两年的NIH资助 每个人。提供额外的机构支持，形式是为受训人员提供学费和津贴，以及 多样性研究金，以支持多样性招聘工作。

Project Summary The goal of this proposal is to implement a novel Research Training in Sensorimotor Neurorehabilitation program to prepare the next generation of scientists that can address the growing need for neuroscience- based rehabilitation solutions. Northwestern University has a long and recognized history in the study of motor control, motor disability and recovery, and neural reorganization; and in training the next generation of movement and rehabilitation scientists (MRS) through the Northwestern University Interdepartmental Neuroscience Program (NUIN) PhD program since 2009, with demonstrated success reflected in more than 20 graduates currently leading successful research careers in academia and industry. The proposed program is built on this research and training record with the mission to train students with clinical and life/applied science backgrounds and post-doctoral fellows with clinical backgrounds to become rehabilitation scientists in basic, translational or clinical research. These scientists will have the ability to integrate knowledge from the various disciplines involved in sensorimotor neurorehabilitation, including neuroscience, engineering and clinical sciences. The training program will focus on four training goals: 1) to provide a thorough grounding in the basic neurobiology of sensorimotor function and control, including translation of insights between animal and human research models; 2) to learn fundamental engineering experimental methods for measurement and analysis of neuronal and musculoskeletal sensory and motor function; 3) to facilitate knowledge sharing in the clinical management of individuals with movement disorders between the post-doctoral and pre-doctoral trainees; and 4) to provide professional development training to support future rehabilitation research career success. The unique structure of the program, couples training of post-doctoral trainees with clinical expertise with pre-doctoral trainees focusing on neuroscience. The program is the first of its kind to provide post-doctoral research training of Doctors of Physical Therapy (DPT), an untapped cohort of prospective scientists that has emerged in the contemporary age of science-based medicine and evidence-based practice. These DPT candidates for post-doctoral slots will be drawn from research intensive Physical Therapy Programs across the United States. Pre-doctoral trainees will be drawn from the NUIN-MRS program. The translational interdisciplinary nature of the program will allow close interaction between clinical investigators and basic and applied sciences investigators, providing a unique opportunity for training in translational research. We intend to support a total of 12 pre-doctoral trainees and 5 post-doctoral trainees with NIH funding for up to two years each. Additional institutional support is available in the form of tuition and stipend supplements for trainees and diversity fellowships to support diversity recruiting efforts.