Developing an App-Based Voice Clinical Decision Support Tool to Augment the Sensitivity of the Bedside Swallow Evaluation in Older Adults

开发基于应用程序的语音临床决策支持工具，以提高老年人床边吞咽评估的灵敏度

• 批准号: 10676194
• 负责人: Anais Rameau
• 金额: $ 24.29万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-04 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10676194
• 关键词: Acoustics; Address; Adult; Advocacy; Affect; Aging; Alzheimer' s disease related dementia; Aspiration Pneumonia; Barium swallow; Behavioral Research; Biological Markers; Caring; Cause of Death; Cellular Phone; Characteristics; Clinical; Collaborations; Coughing; Data; Deglutition; Deglutition Disorders; Dehydration; Dental Hygiene; Detection; Elderly; Environment; Evaluation; Evidence based treatment; Exercise; Fellowship; Food; Foundations; Functional disorder; Funding; Geriatrics; Goals; Grant; Head and Neck Surgery; Health Care Costs; Human; Individual; Institution; Language; Leadership; Length of Stay; Lung; Machine Learning; Malnutrition; Mentors; Mentorship; Methods; Morbidity - disease rate; Nurses; Nursing Assessment; Nursing Homes; Oral; Otolaryngologist; Otolaryngology; Pathologist; Patients; Perception; Performance; Pharyngeal structure; Pilot Projects; Protocols documentation; Research; Research Personnel; Risk; Site; Specialist; Speech; Standardization; Techniques; Technology; Testing; United States National Institutes of Health; Vision; Voice; aspirate; canine model; career; career development; clinical decision support; cohort; cost; curriculum development; dietary; digital; experience; flexibility; frailty; high risk; human old age (65+); improved; improved outcome; interdisciplinary collaboration; interest; medical schools; mobile application; mortality risk; novel strategies; prospective; skills; smartphone application; sound; support tools; tool; treatment strategy; vocal cord

PROJECT SUMMARY/ABSTRACT The over-arching goals of Dr, Rameau's Beeson application are (1) to develop an easy-to-use, highly accurate bedside clinical decision support tool to identify swallowing dysfunction in older adults using analysis of features of their recorded voice, cough and speech, and (2) to become a leader in the nascent field of geriatric otolaryngology with a focus on management of speech and swallowing issues in older adults with Alzheimer's disease and related dementias (AD/ADRD). Candidate: The applicant, Dr. Anaïs Rameau, is an otolaryngologist at Weill Cornell Medical College (WCMC) who has demonstrated significant research ability and clinical interest in geriatric otolaryngology, especially in the care of older adults with dysphagia. Dr. Rameau's long-term career goal is to become an independent researcher and academic leader in geriatric dysphagia. She already laid significant foundations towards this goal, developing close mentorship relationships, gaining broad research, clinical, management and leadership skills, and experience as PI on multiple institutional and foundation grants. Mentors: To achieve her objectives, Dr. Rameau has engaged an exceptional, transdisciplinary team of mentors, who are highly successful, NIH-funded investigators and well-recognized leaders and experts in their respective fields. Her mentorship team includes Dr. Mark Lachs, Co-Director of the WCMC Division of Geriatrics, Dr. Michael Stewart, Chair of the WCM Department of Otolaryngology – Head & Neck Surgery, and Dr. Sara Czaja, Director of the Center on Aging and Behavioral Research at WCM. Research: In collaboration with bio-acousticians at the Cornell Lab of Ornithology, our research, both in an excised canine model and a human pilot study, has suggested that conventional acoustic metrics of voice and cough sound differ in important ways between patients with and without aspiration risk. These characteristics may serve as biomarkers of dysphagia, and acoustic analysis of the patient's digitally recorded voice and cough has the potential to effectively differentiate between normal and abnormal swallowing. Including multiple characteristics, such as those specifically evaluating oral frailty, and combining the results may increase accuracy of swallowing dysfunction identification, especially in older adults with AD/ADRD who are more prone to silent aspiration. Adding non-linear methods and machine learning to conventional acoustic analysis may also improve accuracy. Dr. Rameau proposes to use these techniques to develop a clinical decision support tool that incorporates analysis of multiple characteristics of a patient's recorded voice and cough to determine their aspiration risk. To increase the potential for use of this tool at the bedside, she will modify it for recordings on a smartphone as part of a mobile application. Upon completion of this research, she plans to submit an R01 to prospectively examine the performance of the clinical decision support tool in a multi-site RCT in large, diverse cohort of older adults.

项目总结/文摘

项目成果

Outcomes of Gender-Affirming Voice and Communication Modification Training for Non-binary Individuals: A Case Series.

针对非二元个体的性别肯定声音和沟通修改培训的结果：案例系列。

• DOI: 10.1016/j.jvoice.2023.08.005
• 发表时间: 2023
• 期刊: Journal of voice : official journal of the Voice Foundation
• 作者: Chadwick,KeithA;Liao,David;Alter,IsaacL;Coleman,Rachel;Andreadis,Katerina;Riekki,Rebecca;Waldman,Jack;Rives,Hal;Pitti,Mary;Rameau,Anaïs
• 通讯作者: Rameau,Anaïs

Should Injection Laryngoplasty Be Performed for Acute Unilateral Vocal Fold Paralysis to Improve Swallowing safety?

急性单侧声襞麻痹是否应进行注射喉成形术以提高吞咽安全？

• DOI: 10.1002/lary.30537
• 发表时间: 2023
• 期刊: The Laryngoscope
• 作者: Yiu,Yin;Gorelik,Daniel;Rameau,Anaïs
• 通讯作者: Rameau,Anaïs

Trust in Machine Learning Driven Clinical Decision Support Tools Among Otolaryngologists.

• DOI: 10.1002/lary.31260
• 发表时间: 2024-01
• 期刊: The Laryngoscope
• 作者: Han Chen;Xiaoyue Ma;Hal Rives;Aisha Serpedin;Peter Yao;A. Rameau

Concurrent Validity of a Low-Cost Manometer for Objective Assessments of Respiratory Muscle Strength.

低成本压力计客观评估呼吸肌力量的同时有效性。

• DOI: 10.1002/lary.31106
• 发表时间: 2024
• 期刊: The Laryngoscope
• 作者: Curtis,JamesA;Mocchetti,Valentina;Rameau,Anaïs
• 通讯作者: Rameau,Anaïs

Validation of a 3D-Printed Percutaneous Injection Laryngoplasty Simulator: A Randomized Controlled Trial.

3D 打印经皮注射喉成形术模拟器的验证：随机对照试验。

• DOI: 10.1002/lary.30878
• 发表时间: 2024
• 期刊: The Laryngoscope
• 作者: Kostas,JuliannaC;Lee,AndrewS;Arunkumar,Amit;Han,Catherine;Lee,Mark;Goel,AlexanderN;Alrassi,James;Crosby,Tyler;Clark,ChristineM;Amin,Milan;Abu-Ghanem,Sara;Kirke,Diana;Rameau,Anaïs
• 通讯作者: Rameau,Anaïs