Improving Opioid Use Disorder Treatment for Hospitalized Patients with Endocarditis

改善心内膜炎住院患者的阿片类药物使用障碍治疗

• 批准号: 10684265
• 负责人: Rachel Elizabeth French
• 金额: $ 7.22万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10684265
• 关键词: Accident and Emergency department; Acute; Address; Admission activity; Antibiotics; Caring; Certification; Charge; Clinic; Collaborations; Communities; Data; Development; Dissemination and Implementation; Endocarditis; Evidence based treatment; Expert Opinion; Faculty; Fellowship; Foundations; Goals; Grant; Healthcare; Hospital Costs; Hospitalization; Hospitals; Individual; Infection; Infective endocarditis; Inpatients; Intervention; Interview; Intravenous; Knowledge; Left; Length of Stay; Maps; Medical; Medicine; Mentorship; Methods; Modeling; Morbidity - disease rate; Nurses; Outcome; Pain; Patient Readmission; Patient-Focused Outcomes; Patients; Pennsylvania; Perception; Persons; Physicians; Population; Preparation; Primary Care; Quality of Care; Recovery; Recurrence; Registered nurse; Research; Research Institute; Research Personnel; Scholarship; School Nursing; Social Workers; Specialist; Structure; Substance Use Disorder; Training; Training Activity; Treatment Efficacy; United States; Universities; University Hospitals; Vulnerable Populations; Withdrawal; Work; Writing; care delivery; career; cost; design; economic evaluation; effective therapy; effectiveness/implementation trial; efficacy testing; evidence base; high risk; hospital care; hospital patient care; hospitalization rates; implementation framework; implementation science; implementation strategy; improved; improved outcome; injection drug use; inpatient service; model design; mortality; mortality risk; opioid epidemic; opioid injection; opioid use; opioid use disorder; patient engagement; patient oriented; programs; skills; treatment program

PROJECT SUMMARY/ABSTRACT Patients hospitalized for opioid use disorder-associated infective endocarditis (OUD-IE) have distinctly poor outcomes and high costs. Despite the availably of effective treatment for opioid use disorder and the opportunity to intervene during hospitalization, health care staff tend not to address opioid use disorder during hospitalization for OUD-IE. Existing models of hospital care for patients with opioid use disorder can inform hospital care delivery for OUD-IE patients, though significant adaptation of these models is needed to meet the unique needs of OUD- IE patients related to their prolonged hospital stays. Little is known regarding how to best deploy evidence-based opioid use disorder interventions for medically hospitalized patients. The aims of the proposed study are to: 1) Characterize current practices of health care staff regarding hospital care delivery for OUD-IE patients; 2) Examine the appropriateness, feasibility, and acceptability of implementing evidence-based opioid use disorder care for hospitalized OUD-IE patients; and 3) Adapt an intervention for hospitalized OUD-IE patients and develop a corresponding toolkit of implementation strategies. To accomplish these aims, I will engage health care staff who care for OUD-IE patients at the Hospital of the University of Pennsylvania and will rely on mentorship and collaborators from faculty in the University of Pennsylvania's Schools of Nursing and Medicine. Qualitative data, in conjunction with expert opinion, will be integrated to inform an adapted opioid use disorder intervention for OUD-IE patients and a corresponding toolkit of implementation strategies. Findings from this study will increase the currently limited efficacy of care delivery for hospitalized patients with opioid use disorder and ultimately enhance their outcomes. This program of research and corresponding training activities will facilitate the applicant's long-term goal of pursuing an academic research career committed to improving the quality of care and outcomes for hospitalized people with substance use disorders through implementation science. Specific training goals are to: 1) Understand current practices for care delivery for hospitalized patients with OUD; 2) Acquire a strong foundation in methods for the proposed project and for future research; 3) Develop skills related to designing and implementing new practices in hospitals; and 4) Integrate professional development, grant writing, and scholarship to prepare to be an independent researcher.

项目总结/文摘

项目成果

Adapting psychotherapy in collaborative care for treating opioid use disorder and co-occurring psychiatric conditions in primary care.

在协作护理中采用心理治疗，治疗阿片类药物使用障碍和初级护理中并发的精神疾病。

• DOI: 10.1037/fsh0000791
• 发表时间: 2023
• 期刊: Families, systems & health : the journal of collaborative family healthcare
• 作者: French,Rachel;Worley,Julie;Lowenstein,Margaret;Bogner,HillaryR;Calderbank,Tara;DePhilippis,Dominick;Forrest,Andrew;ConnollyGibbons,MaryBeth;Harris,RebeccaArden;Heywood,Saida;Kampman,Kyle;Mandell,DavidS;McKay,JamesR;Newman,
• 通讯作者: Newman,

"I Just Need Proper Treatment": Being Hospitalized for Endocarditis among Individuals Who Inject Drugs Being Hospitalized for Endocarditis.

“我只需要适当的治疗”：注射药物因心内膜炎住院的个体中因心内膜炎住院。

• DOI: 10.1007/s11606-023-08133-3
• 发表时间: 2023
• 期刊: Journal of general internal medicine
• 影响因子: 5.7
• 作者: French,Rachel;McFadden,Rachel;Stewart,Rebecca;Christian,Hanna;Compton,Peggy
• 通讯作者: Compton,Peggy

"Because of this rotation, this is what I want to do": Implementation and evaluation of a telehealth opioid use disorder clinical placement for nurse practitioner students.

“因为这次轮换，这就是我想做的事情”：为护士实习生实施和评估远程医疗阿片类药物使用障碍临床安置。

• DOI: 10.1097/jxx.0000000000000949
• 发表时间: 2023
• 期刊: Journal of the American Association of Nurse Practitioners
• 影响因子: 1.2
• 作者: French,Rachel;Lyons,Erica;Schachter,Allison;Treston,JuneA;Marshall,Ami;Lattimer,Jennie;Bisaga,Adam;Behar,Emily;Aronowitz,ShoshanaV
• 通讯作者: Aronowitz,ShoshanaV

"I wouldn't need Narcan for myself, but I can have it for somebody else:" perceptions of harm reduction among hospitalized patients with OUD.

• DOI: 10.1186/s13722-023-00395-w
• 发表时间: 2023-06-24
• 期刊: ADDICTION SCIENCE & CLINICAL PRACTICE
• 影响因子: 3.7
• 作者: French, Rachel;Davis, M. Holliday;Aronowitz, Shoshana V.;Crowe, Molly;Abrams, Matthew;Edwards, Grace;Lowenstein, Margaret
• 通讯作者: Lowenstein, Margaret

Opportunities to improve opioid use disorder care for hospitalised patients with endocarditis.

• DOI: 10.1136/bmjoq-2023-002420
• 发表时间: 2023-12-18
• 期刊: BMJ open quality
• 影响因子: 1.4