Implementation Science Core [Parent Title: PREVENTING INFANT INFECTIONS WITH IMPLEMENTATION SCIENCE IN MALAWI]

实施科学核心 [父标题：在马拉维通过实施科学预防婴儿感染]

基本信息

批准号：
10701193
负责人：
Brian W Pence
金额：
$ 20.31万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-05-15 至 2028-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10701193
关键词：
Address Applied Research Breast Feeding Clinical Sciences Data Collection Development Ensure Evaluation Evidence based intervention Fellowship Funding Goals Guidelines HIV Institution International Internships Intervention Knowledge Learning Malawi Manuscripts Measurement Mental Health Mentors Monitor North Carolina Outcome Parents Prevention Research Research Design Research Personnel Research Project Grants Resources Science Scientist Series Testing Training Training Programs Translating Translational Research Translations United States National Institutes of Health Validation Vertical Disease Transmission Wit Woman doctoral student evidence base experience implementation evaluation implementation facilitation implementation intervention implementation measures implementation outcomes implementation research implementation science implementation strategy improved infant infection innovation meetings member organizational readiness postnatal prevent programs protocol development real world application scale up skills synergism tool

项目摘要

Implementation Science Core – Summary Many interventions have been developed and tested for elimination of mother-to-child transmission but the translation and implementation of these interventions into real-world settings has remained limited. Implementation science provides the necessary tools to ensure that interventions are implemented well and their impact in real-world settings is realized. The goal of the implementation science core is to provide scientific support to each of the PRI3SM implementation science research projects to ensure the latest principles and approaches in implementation science are applied appropriately to maximize the impact of the research projects through the following aims: Aim 1. To provide support and resources to enable investigators at UNC Project Malawi to effectively implement evidence-based EMTCT interventions. The implementation science core will provide assistance with selection and application of implementation science study designs to guide protocol development; identification, selection, and adaptation of implementation strategies to facilitate implementation of PRI3SM projects; selection of appropriate implementation outcomes and assistance in the development and validation of data collection tools for measuring implementation outcomes of the PRI3SM projects; implementation, monitoring and evaluation of evidence-based PRI3SM interventions in real-world settings; identification of key barriers and facilitators to implementing PRI3SM interventions; organizational readiness assessments for implementation of the PRI3SM projects and supporting qualitative measurement of implementation science outcomes and construct such as acceptability, feasibility, barriers and facilitators and organizational readiness. Aim 2: To provide trainees and junior investigators from existing local IS training programs with opportunities for real-world application of implementation science concepts. The Implementation Science Core will provide internship and fellowship placements and mentored experiential training in implementation science for junior investigators such as master’s and PhD students and graduates from existing implementation science training programs. The Implementation Science Core will leverage the capacity building program for PRI3SM to fully establish an Implementation Science Unit at UNC Project Malawi for ongoing support with implementation science training and resources. The ongoing support will include formal meetings and a seminar series with trainees to provide a platform for exchange of skills and experiences, presentations on projects and relevant implementation science topics, and review of manuscripts.

实施科学核心 - 摘要已经开发并测试了许多干预措施，以消除母亲到孩子的传播，但将这些干预措施转换和实施为现实世界的设置仍然有限。实施科学提供了必要的工具，以确保干预措施得到很好的实施，并且实现了它们在现实环境中的影响。实施科学核心的目的是提供对每个PRI3SM实施科学研究项目的科学支持，以确保最新适当地应用了实施科学的原则和方法，以最大化通过以下目的进行研究项目：目的1。提供支持和资源，以使马拉维UNC项目的调查人员有效地实施基于证据的EMTCT干预措施。实施科学核心将提供帮助通过选择和应用实施科学研究设计来指导协议开发；识别，选择和适应实施策略以促进PRI3SM的实施项目；选择适当的实施成果和在开发和验证方面的帮助用于衡量PRI3SM项目实施结果的数据收集工具；执行，在现实世界中监视和评估基于证据的PRI3SM干预措施；键的识别实施PRI3SM干预措施的障碍和促进者；组织准备评估 PRI3SM项目的实施并支持实施科学的定性测量结果和构建，例如可接受性，可行性，障碍和促进者以及组织准备。目标2：为现有本地的受训人员和初级调查员提供培训计划实施科学概念的实际应用机会。实施科学核心将提供实习和奖学金安置，并修改专家培训初级调查人员的实施科学，例如硕士和博士生以及毕业生现有的实施科学培训计划。实施科学核心将利用 PRI3SM的能力构建计划，以完全建立MALAWI的UNC项目的实施科学部门为实施科学培训和资源提供持续的支持。持续的支持将包括正式的会议和开创性的系列培训，以提供技能交换的平台经验，有关项目的演讲和相关实施科学主题以及手稿的审查。