SCH: A personalized wearable rehabilitation sensing system for stroke survivors

在美国，每年约有80万人患有脑中风， 每年的成本约为330亿美元。中风也是残疾的主要原因，大多数中风幸存者表现出 尽管中风后进行了广泛的康复，但仍存在持续的运动障碍。因此，独立生活 大多数中风幸存者重返工作岗位的机会有限。大多数中风幸存者 上肢和下肢运动障碍，范围从无法触及和抓握物体到有限的 阿姆斯壮尽管在临床上进行了广泛的康复治疗，这些持续性损伤仍然严重 限制独立生活，部分原因是临床环境中的培训效果无法有效转移 日常生活活动（ADL）。此外，在慢性病中无法执行基本的日常功能， 由于肢体废用和/或神经肌肉的适应不良， 系统我们假设，一个持续的康复训练，是融入社区生活（例如， 在家里，在购物中心，或在公园）可以利用诊所康复效果，并提高日常生活质量。 中风幸存者的功能。 本项目的目标是开发一个个性化的基于社区的康复传感系统， 改善这些人的日常功能。因此，我们的建议直接涉及NICHD科学 研究主题5：为残疾人提供安全有效的治疗和设备。我们 寻求一种佩戴舒适、操作中功率低、并且使用友好的真正可佩戴的系统（例如， 通过智能手机）。该系统将包括三个基本组成部分： 可穿戴传感器网络监测手臂和腿部功能活动;低功耗数据采集， 处理和传输协议;以及智能手机APP，用于将培训结果传达给 用户和临床医生通过互联网，并从他们那里获得反馈。具体而言，我们提出以下目标。 目标1：开发真正的可穿戴传感器网络，可以监测涉及受影响的身体活动 和中风幸存者对侧的肢体。目标2：将多模态传感网络集成到一个 这是一个连贯的系统，并有效地传达传感器数据。目标3：从图像中提取显著特征 获取运动活动信息，并提供个性化的社区康复指导。目标4： 评价系统性能和临床可行性。 相关性（参见说明）： 这项研究的结果可以改变中风幸存者的个性化康复， 真正的可穿戴系统，可在各种社区环境中进行持续康复，这可以实现远程康复。 康复，并最大限度地恢复中风幸存者的功能。可穿戴式身体活动跟踪 承诺医疗保健和福祉的范式转变。我们系统的用户友好性还可以 便于在其他运动障碍的临床人群中广泛应用。

In the United States, there are about 800,000 people per year suffering a cerebral stroke, and the associated cost is about $33 billion per year. Stroke is also a leading cause of disability, and most stroke survivors exhibit persistent motor impairments despite extensive rehabilitation after the stroke. As a result, independent living and return to the work force is limited in a majority of stroke survivors. A majority of stroke survivors exhibit upper and lower limb motor impairments, ranging from incapability of reaching and grasping objects to limited ambulation. Despite extensive rehabilitation therapy in the clinic, these persistent impairments still severely limit independent living, partly because the training effect in the clinical setting is not effectively transferred to activities of daily living (ADL). Furthermore, the inability to perform essential daily functions at the chronic stage can further exacerbate the impairment, due to limb disuse and/or maladaptation of the neuromuscular system. We hypothesize that a continuous rehabilitation training that is integrated into community living (e.g., at home, in the shopping mall, or at the park) can capitalize the clinic rehabilitation effect and enhance daily functions of stroke survivors. The goal of this project is to develop a personalized community-based rehabilitation sensing system to improve daily functions of these individuals. Thus, our proposal directly addresses the NICHD scientific research theme 5: Advancing Safe and Effective Therapeutics and Devices for People with Disabilities. We seek a truly wearable system that is comfortable to wear, low power in operation, and friendly to use (e.g., via smartphones). The system will include three essential components: a nanomaterial-enabled multimodal wearable sensor network to monitor arm and leg functional activities; a low-power data acquisition, processing, and transmission protocol; and a smart phone APP to communicate training outcomes to the users and clinicians via internet and receive feedback from them. Specifically, we propose the following aims. Aim 1: To develop truly wearable sensor network that can monitor the physical activities involving the affected and contralateral limbs of stroke survivors. Aim 2: To integrate the multi-modality sensing network into a coherent system and efficiently communicate the sensor data. Aim 3: To extract prominent features from the acquired motor activity information and provide personalized community rehabilitation guidance. Aim 4: To evaluate the system performance and clinical feasibility. RELEVANCE (See instructions): The outcome of the proposed research could transform personalized rehabilitation of stroke survivors with a truly wearable system for continuous rehabilitation at various community settings, which could enable tele- rehabilitation, and maximize functional recovery of stroke survivors. Wearable physical activity tracking promises a paradigm shift for healthcare and wellbeing. The user-friendly nature of our system can also facilitate wide applications in other clinical populations with motor impairment.