CORALE-SeroNet Admin Core

CORALE-SeroNet 管理核心

• 批准号: 10688395
• 负责人: Susan Cheng
• 金额: $ 31.71万
• 依托单位: CEDARS-SINAI MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-30 至 2024-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10688395
• 关键词: 2019-nCoV; Address; Administrative Coordination; Advisory Committees; Advocate; Annual Reports; Basic Science; Bioinformatics; Budgets; COVID-19 susceptibility; Clinical Research; Clinical Sciences; Collaborations; Communication; Communities; Data Set; Educational workshop; Ensure; Evaluation; Feedback; Generations; Goals; Immune; Immunity; Inflammatory Response; Infrastructure; Investigation; Knowledge; Leadership; Letters; Monitor; Participant; Patients; Policies; Population Sciences; Preparation; Productivity; Progress Reports; Publications; Reporting; Research; Research Personnel; Research Project Grants; Resource Allocation; Resource Sharing; Resources; Scientist; Services; Structure; Therapeutic; Training Activity; Translating; Translational Research; Translations; Vision; Work; biobank; data dissemination; data sharing; meetings; operation; organizational structure; programs; public repository; recruit

ABSTRACT for Administrative Core The Administrative Core will provide a centralized, coordinated infrastructure for effectively supporting, evaluating, and stimulating progress towards the overall scientific goals of the CORALE-SeroNet U54 Program. The Core led by the Program Directors (Drs. Susan Cheng, Jane Figueiredo, and Michael Karin) will interact with Internal and External Advisory Committees and a Community Advisory Board and will provide regular feedback on programmatic initiatives and progress toward achieving the following goals. First, to provide leadership to ensure overall program productivity and effective collaboration across the SeroNET consortium. The Administrative Core will provide: (a) centralized and efficient administrative support and coordination of all CORALE-U54 activities and all collaborative efforts across the SeroNet consortium; (b) regular monitoring and evaluation of all project activities and generation of reports for internal and external stakeholders including assessments of opportunities for translation between basic and clinical research and the most effective allocation of resources; (c) engagement with advisory committees and external organizations, including other SeroNet centers and external investigators regarding progress toward the overall goals of SeroNet and opportunities for augmenting or integrating scientific and training activities; (d) financial administrative support to ensure appropriate management of budgets and financial resources; (e) support to ensure research compliance and integrity of all research programs; and, (f) administrative coordination for the dissemination of data and results, including data sharing and publication of all research findings. In particular, the Leadership Administrative Core has an active communication plan and resources for disseminating our ongoing findings to the broader clinical, research and lay communities. Second, the Administrative core will provide organizational structure and management support for the Resource Cores. The Administrative Core will provide an efficient and centralized administrative structure to support all activities of the two Cores: (a) Recruitment and Biobanking Core (RBC), and (b) the Immune Bioanalytics Core (IBC). Thirdly. The Administrative Core will provide organizational structure and management to collaborate within SeroNet and beyond. Our vision is to develop and manage a research program that will integrate our team of population, clinical, translational, and basic science scientists and unique patients resources with the broader scientific community led by SeroNET to meet the urgent need to understand the underlying mechanisms and potential therapeutic approaches to address key knowledge gaps regarding SARS-CoV-2 susceptibility and potential for immunity.

《行政核心摘要》 行政核心将提供一个集中、协调的基础设施，以有效地支持、 评估和激励朝着Corale-SeroNet U54计划的总体科学目标取得的进展。 由项目主任(苏珊·程博士、简·菲格雷多博士和迈克尔·卡林博士)领导的核心将进行互动 与内部和外部咨询委员会以及社区咨询委员会合作，并将定期提供 关于方案倡议和实现以下目标的进展的反馈。第一，提供 领导力，以确保整个SeroNET联盟的整体计划生产力和有效协作。 行政核心将提供：(A)集中和有效的行政支助和协调 Corale-U54活动和整个SeroNet财团的所有协作努力；(B)定期监测和 评价所有项目活动并为内部和外部利益攸关方生成报告，包括 评估基础研究和临床研究之间的转换机会和最有效的分配 (C)与咨询委员会和外部组织，包括其他SeroNet组织接触 中心和外部调查人员关于实现SeroNet总体目标的进展情况和机会 加强或整合科学和培训活动；(D)提供财政行政支助，以确保 适当管理预算和财政资源；(E)支持确保研究合规和 所有研究方案的完整性；(F)传播数据和成果的行政协调， 包括数据共享和所有研究成果的发布。尤其是领导行政核心 有积极的沟通计划和资源，将我们正在进行的研究成果传播给更广泛的临床， 研究和外行社区。第二，行政核心将提供组织结构和 对资源核心的管理支持。行政核心将提供高效和集中的 支持两个核心的所有活动的行政结构：(A)征聘和生物库核心(RBC)， (B)免疫生物分析核心(IBC)。第三点。行政核心将提供组织 在SeroNet内外进行协作的结构和管理。我们的愿景是开发和管理一个 研究计划将整合我们的人口、临床、转化和基础科学科学家团队 和独特的患者资源与以SeroNET为首的更广泛的科学界合作，以满足以下迫切需求 了解解决关键知识差距的潜在机制和潜在的治疗方法 关于SARS-CoV-2的易感性和免疫潜力。