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The DREAM study began on 9/16/2019. 10 drugs have been tested for their ability to lower the risk of Alzheimer's disease and related dementias (ADRD). These drugs are commonly used to treat rheumatoid arthritis. Encouraging results from one of the drugs tested are being confirmed through parallel validation experiments in cell culture based assays. The next set of analyses will test commonly used anti-asthma drugs. Due to delays arising from the COVID-19 pandemic, a no-cost extension of 9-months has been granted to allow for the completion of proposed analyses of 20 candidate drugs.
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New Cures from Old Medicines - Targeting abnormal metabolism in AD
  • 批准号:
    10019244
  • 项目类别:
  • 资助金额:
    $10.82万
  • 财政年份:
    --
  • 负责人:
    Madhav Thambisetty
  • 依托单位:
Understanding mechanisms and seeking novel biomarkers in Alzheimer's disease
  • 批准号:
    10688757
  • 项目类别:
  • 资助金额:
    $18.99万
  • 财政年份:
    --
  • 负责人:
    Madhav Thambisetty
  • 依托单位:
Understanding mechanisms and seeking novel biomarkers in Alzheimer's disease
  • 批准号:
    10250845
  • 项目类别:
  • 资助金额:
    $296.2万
  • 财政年份:
    --
  • 负责人:
    Madhav Thambisetty
  • 依托单位:
Understanding mechanisms and seeking novel biomarkers in Alzheimer's disease
  • 批准号:
    9351926
  • 项目类别:
  • 资助金额:
    $89.46万
  • 财政年份:
    --
  • 负责人:
    Madhav Thambisetty
  • 依托单位:
国内基金
海外基金
新型F-18标记香豆素衍生物PET探针的研制及靶向Alzheimer's Disease 斑块显像研究
  • 批准号:
    81000622
  • 项目类别:
    青年科学基金项目
  • 资助金额:
    20.0万元
  • 批准年份:
    2010
  • 负责人:
    梁胜
  • 依托单位:
阿尔茨海默病(Alzheimer's disease,AD)动物模型构建的分子机理研究
  • 批准号:
    31060293
  • 项目类别:
    地区科学基金项目
  • 资助金额:
    26.0万元
  • 批准年份:
    2010
  • 负责人:
    郭亚芬
  • 依托单位:
跨膜转运蛋白21(TMP21)对引起阿尔茨海默病(Alzheimer'S Disease)的γ分泌酶的作用研究