Developing Internet-Delivered, Mindfulness-based Intervention to Reduce HIV Risk and Promote Mental and Sexual Health among Young Adult MSM
制定基于互联网的正念干预措施,以降低年轻男男性接触者的艾滋病毒风险并促进心理和性健康
基本信息
- 批准号:10693117
- 负责人:
- 金额:$ 16.84万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-09-01 至 2025-08-31
- 项目状态:未结题
- 来源:
- 关键词:AIDS preventionAddressAdherenceAffectAgeAnxietyBenchmarkingBiological MarkersBisexualClinicalClinical TrialsCounselingDataDevelopmentDiagnosticDisclosureDiscriminationDisparityDistressEducational workshopEpidemicEvaluationFeedbackFocus GroupsFoundationsFundingFutureGaysGrantHIVHIV InfectionsHIV SeronegativityHIV SeropositivityHIV riskHairHealthHealth PromotionHealth ServicesHealth educationHomeHuman immunodeficiency virus testHydrocortisoneImpulsivityIndividualInstitutionInternetInterventionK-Series Research Career ProgramsLeadLinkLongevityMental DepressionMental HealthMental disordersMental health promotionMentored Patient-Oriented Research Career Development AwardMentorsMentorshipMethodsMindfulness TrainingMinority GroupsModelingNational Center for Complementary and Integrative HealthPatient Self-ReportPersonsPhasePhysiologicalPhysiologyPopulationPrevention strategyProcessProductionProtocols documentationProviderPublic HealthPublic Health SchoolsRandomizedResearchResearch PersonnelResourcesRiskSamplingScientistSeriesSexual HealthStigmatizationStressStress and CopingTestingTrainingUnderserved PopulationUniversitiesWorkacceptability and feasibilitybehavioral healthbehavioral health interventionbiological adaptation to stressbiopsychosocialcareerclinical developmentclinical efficacyclinical trial implementationcondomless anal sexcopingdesigndiagnostic strategydisorder preventionefficacious interventionefficacy studyemotion dysregulationevidence baseexperiencefeasibility trialhealth disparityhigh riskimprovedinnovationinternalized stigmaintervention refinementmarginalized communitymen who have sex with menmindfulnessmindfulness interventionmindfulness-based stress reductionminority healthminority stresspilot testpopulation healthpre-exposure prophylaxispreventive interventionprimary outcomeprotocol developmentpsychological distresspsychological symptomrecruitresearch and developmentsample collectionsexual risk behaviorsocial stigmastress reductionsubstance usesyndemicyoung adultyoung men who have sex with men
项目摘要
PROJECT SUMMARY
Young men who have sex with men (YMSM; age 18-34) are disproportionately burdened by HIV. Minority stress and its “downstream” effects in YMSM, including mental health issues, sexual risk behaviors, and suboptimal HIV testing, contribute to the syndemic risks surrounding HIV. Mindfulness-based interventions (MBIs), adapted for HIV prevention among YMSM and internet-based delivery to maximize reach and engagement, could offer an innovative and scalable method to address this public health issue. Consistent with NCCIH’s scientific priority in Disease Prevention and Health Promotion across Lifespan, the current project aims to develop an internet-delivered MBI for HIV prevention among distressed, high-risk YMSM. Specifically, this K23 will provide support for an early phase, exploratory clinical trial by adapting mindfulness-based stress reduction (MBSR) and conducting a feasibility trial among YMSM. Candidate: Dr. Sun is a clinical scientist with a research background in HIV prevention and mental health concerning minority populations and marginalized communities. In recent years, she has pursued clinical and research development in mindfulness. Building on her prior work, she is applying for a five-year K23 Career Development Award to obtain training, mentorship, and research experience to become an expert in adapting and evaluating internet-delivered MBI to address HIV-related health disparities and an independent investigator capable of R01 funding. Mentoring: A stellar team of senior investigators serve on the advisory panel. Drs. Don Operario and Judson Brewer are co-primary mentors, who have complimentary expertise in HIV prevention for MSM and internet-based MBI for behavioral health. Three co-mentors bring expertise in internet-based HIV intervention with young adults (Dr. Larry Brown), mindfulness for population health (Dr. Eric Loucks), and stress physiology (Dr. Audrey Tyrka). Research: Guided by the ADAPT-ITT model, the proposed project aims to (1) adapt MBSR for distressed, high risk YMSM and internet-delivery using focus groups with YMSM (n=30) and stakeholders (n=16), (2) refine the intervention protocol by administering adapted materials to distressed, high risk YMSM (n=18) and stakeholders (n=16) via theatre testing, and (3) examine the feasibility and acceptability of the adapted iMBI for HIV prevention by randomizing 40 distressed, high-risk YMSM to the iMBI (n=20) and a Health Education condition (n=20). The study will examine recruitment and retention, intervention adherence (e.g., attendance, at-home practice), completion of assessment (HIV testing, sexual risk behaviors, hair sample collection, mental health, minority stress and coping), and acceptability of the intervention. Trainings: Dr. Sun will receive training in MBSR, intervention adaptation and implementation for YMSM and internet-delivery, and a biopsychosocial-based understanding of stress through coursework, seminars, workshops, directed readings, and mentored research. Guided by an excellent mentorship team, these training and research experiences will establish the candidate’s career as an expert in HIV-related behavioral health and iMBI for minority health. The candidate is institutionally supported by Brown University School of Public Health.
项目摘要
男男性行为青年(18-34岁)感染艾滋病毒的比例过高。少数民族的压力及其“下游”影响YMSM,包括心理健康问题,性风险行为,和次优的艾滋病毒检测,有助于周围的艾滋病毒的综合风险。基于正念的干预措施(MBI)适用于YMSM中的艾滋病毒预防和基于互联网的交付,以最大限度地扩大覆盖范围和参与度,可以提供一种创新且可扩展的方法来解决这一公共卫生问题。与NCCIH在疾病预防和终身健康促进方面的科学优先事项相一致,目前的项目旨在开发一种互联网交付的MBI,用于在痛苦的高危YMSM中预防艾滋病毒。具体来说,K23将通过调整基于正念的减压(MBSR)并在YMSM中进行可行性试验,为早期探索性临床试验提供支持。候选人:孙博士是一名临床科学家,研究背景是少数民族和边缘化社区的艾滋病毒预防和心理健康。近年来,她一直致力于正念的临床和研究发展。在她以前的工作的基础上,她正在申请一个为期五年的K23职业发展奖,以获得培训,指导和研究经验,成为适应和评估互联网提供的MBI的专家,以解决与艾滋病毒相关的健康差距和独立调查员能够R 01资金。指导:一个由高级调查员组成的一流团队在咨询小组中任职。Don Operario博士和Judson Brewer博士是共同的主要导师,他们在MSM的艾滋病毒预防和基于互联网的行为健康MBI方面拥有丰富的专业知识。三位共同导师带来了基于互联网的艾滋病毒干预与年轻人(拉里布朗博士),人口健康的正念(埃里克劳克斯博士)和压力生理学(奥黛丽蒂尔卡博士)的专业知识。调研:在ADAPT-ITT模型的指导下,拟议的项目旨在(1)使用YMSM(n=30)和利益相关者(n=16)的焦点小组调整MBSR用于苦恼的高风险YMSM和互联网交付,(2)通过剧院测试向苦恼的高风险YMSM(n=18)和利益相关者(n=16)管理改编的材料来完善干预方案,(3)将40例抑郁高危YMSM随机分为iMBI组(n=20)和健康教育组(n = 20),研究iMBI预防HIV感染的可行性和可接受性。该研究将检查招募和保留,干预依从性(例如,参与、在家实践)、完成评估(艾滋病毒检测、性风险行为、头发样本采集、心理健康、少数民族压力和应对)以及干预措施的可接受性。培训:孙博士将通过课程、研讨会、讲习班、指导性阅读和指导性研究接受MBSR、YMSM和互联网交付的干预适应和实施以及基于生物心理社会的压力理解方面的培训。在优秀的导师团队的指导下,这些培训和研究经验将使候选人成为艾滋病毒相关行为健康和iMBI少数民族健康专家。这位候选人得到了布朗大学公共卫生学院的机构支持。
项目成果
期刊论文数量(17)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Experiences of stigma, psychological distress, and facilitative coping among pregnant people with gestational diabetes mellitus.
- DOI:10.1186/s12884-023-05949-z
- 发表时间:2023-09-07
- 期刊:
- 影响因子:3.1
- 作者:
- 通讯作者:
Selecting and describing control conditions in mobile health randomized controlled trials: a proposed typology.
- DOI:10.1038/s41746-023-00923-7
- 发表时间:2023-09-30
- 期刊:
- 影响因子:15.2
- 作者:
- 通讯作者:
Mindfulness-Based Mobile Health to Address Unhealthy Eating Among Middle-Aged Sexual Minority Women With Early Life Adversity: Mixed Methods Feasibility Trial.
基于正念的移动健康,以解决患有早期生命逆境的中年性少数民族妇女中不健康的饮食:混合方法可行性试验。
- DOI:10.2196/46310
- 发表时间:2023-09-26
- 期刊:
- 影响因子:7.4
- 作者:Sun, Shufang;Nardi, William;Murphy, Matthew;Scott, Ty;Saadeh, Frances;Roy, Alexandra;Brewer, Judson
- 通讯作者:Brewer, Judson
Mobile phone-based interventions for mental health: A systematic meta-review of 14 meta-analyses of randomized controlled trials.
- DOI:10.1371/journal.pdig.0000002
- 发表时间:2022-01-01
- 期刊:
- 影响因子:0
- 作者:Goldberg, Simon B;Lam, Sin U;Sun, Shufang
- 通讯作者:Sun, Shufang
Mental Health Problems of HIV Healthcare Providers During the COVID-19 Pandemic: The Interactive Effects of Stressors and Coping.
- DOI:10.1007/s10461-020-03073-z
- 发表时间:2021-01
- 期刊:
- 影响因子:4.4
- 作者:Mi T;Yang X;Sun S;Li X;Tam CC;Zhou Y;Shen Z
- 通讯作者:Shen Z
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Shufang Sun其他文献
Shufang Sun的其他文献
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{{ truncateString('Shufang Sun', 18)}}的其他基金
Developing Internet-Delivered, Mindfulness-based Intervention to Reduce HIV Risk and Promote Mental and Sexual Health among Young Adult MSM
制定基于互联网的正念干预措施,以降低艾滋病毒风险并促进年轻男男性接触者的心理和性健康
- 批准号:
10675151 - 财政年份:2020
- 资助金额:
$ 16.84万 - 项目类别:
Developing Internet-Delivered, Mindfulness-based Intervention to Reduce HIV Risk and Promote Mental and Sexual Health among Young Adult MSM
制定基于互联网的正念干预措施,以降低年轻男男性接触者的艾滋病毒风险并促进心理和性健康
- 批准号:
10471408 - 财政年份:2020
- 资助金额:
$ 16.84万 - 项目类别:
Developing Internet-Delivered, Mindfulness-based Intervention to Reduce HIV Risk and Promote Mental and Sexual Health among Young Adult MSM
制定基于互联网的正念干预措施,以降低年轻男男性接触者的艾滋病毒风险并促进心理和性健康
- 批准号:
10082672 - 财政年份:2020
- 资助金额:
$ 16.84万 - 项目类别:
Developing Internet-Delivered, Mindfulness-based Intervention to Reduce HIV Risk and Promote Mental and Sexual Health among Young Adult MSM
制定基于互联网的正念干预措施,以降低年轻男男性接触者的艾滋病毒风险并促进心理和性健康
- 批准号:
10248557 - 财政年份:2020
- 资助金额:
$ 16.84万 - 项目类别:
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