Core A: Administrative Core

项目摘要 行政核心的目的是提供行政监督和行政支持的所有孢子， 胰腺癌的治疗方法行政核心将监督所有方案的活动 组成部分，确保遵守当地和联邦赠款管理指南，并促进 项目成员之间的沟通和协作。行政核心的具体目标是： 目标1：促进SPORE内部和内部的沟通、协作和会议。这个核心将是 负责分发SPORE相关材料、议程、监管信息、进度报告，以及 出版物的孢子教师和工作人员。我们将协调双月工作组会议，每月SPORE 指导委员会会议和年度务虚会，以促进交流意见和利用共享资源。 我们将协调外部顾问委员会和内部顾问委员会。我们将继续致力于 网站，提供最新进展和联系信息，向调查人员分发季度最新情况 突出生物样本（核心B）和生物统计学和生物信息学（核心C）提供的资源 核心，并促进生物标本样本和信息的双向流动。该核心还将提供 多机构SPORE临床试验的行政监督。 目标2：为“孢子”方案的所有组成部分提供行政和财政监督及支助。我们将互动 与华盛顿大学的赠款和合同办公室和国家癌症研究所的工作人员一起准备和 提交年度进度报告，并根据需要完成其他项目。 目标3：协调SPORE发展研究计划和职业发展计划 行政活动。该核心将征求申请并协调职业提升的审查 计划（CEP）和发展研究计划（DRP）。这个核心将监控获奖者的进展， 协调获奖者前往其他SPORE机构的旅行，并促进获奖者使用核心资源。 目标4：加强代表性不足的少数民族参与所有宣传教育和体育运动的活动。核心会监督 DRP和CEP倡议促进少数人参与SPORE临床试验和胰腺癌 research.我们将通过领导、社区外展和教育、临床服务， 临床试验应计审计，支持差异研究，保留和招募少数民族，以及 与机构资源差距的沟通。 目标5：确保在与患者参与者的研究的各个方面都解决宣传问题。的 核心将确保所有的SPORE组件适当地纳入宣传问题或关注。我们将 通过两种方式实现这一点，包括患者倡导和患者反馈。 目标6：协助研究者准备学术报告、出版物、法规文件， 以及其他与孢子相关的产品。该核心将负责完成所需的文件 研究者出席地方和国家会议并向机构监管部门提交文件 主体（例如，人类和动物研究方案）、出版物和最终同行评审手稿 在接受后立即由SPORE资金支付给PubMed Central。

PROJECT SUMMARY The Administrative Core aims to provide executive oversight and administrative support for all SPORE in Pancreatic Cancer projects and cores. The Administrative Core will monitor the activities of all program components, ensure compliance with local and federal grant administration guidelines, and facilitate communication and collaboration among program members. The specific aims of the Administrative Core are: Aim 1: Facilitate intra- and inter-SPORE communication, collaboration, and meetings. This core will be responsible for distributing SPORE-related materials, agendas, regulatory information, progress reports, and publications to SPORE faculty and staff. We will coordinate bi-monthly working group meetings, monthly SPORE Steering Committee meetings, and an annual retreat to facilitate exchange of ideas and use of shared resources. We will coordinate the External Advisory Board and Internal Advisory Board. We will maintain a dedicated website to provide progress updates and contact information, distribute quarterly updates to investigators highlighting resources available through the Biospecimen (Core B) and Biostatistics & Bioinformatics (Core C) Cores, and facilitate bidirectional flow of biospecimen samples and information. This core will also provide administrative oversight of multi-institution SPORE clinical trials. Aim 2: Provide administrative and fiscal oversight and support for all SPORE components. We will interact with Washington University's Grants and Contracts Office and National Cancer Institute staff to prepare and submit annual progress reports and complete other projects as needed. Aim 3: Coordinate the SPORE Developmental Research Program and Career Enhancement Program administrative activities. This core will solicit applications and coordinate review for the Career Enhancement Program (CEP) and Developmental Research Program (DRP). This core will monitor awardee progress, coordinate awardees’ travel to peer SPORE institutions, and facilitate use of core resources by awardees. Aim 4: Enhance participation of underrepresented minorities in all SPORE activities. The Core will oversee DRP and CEP initiatives to promote minority participation in SPORE clinical trials and pancreatic cancer research. We will accomplish this through leadership, community outreach and education, clinical services, clinical trial accrual auditing, support of disparities research, retention and recruitment of minorities, and communication with institutional disparities resources. Aim 5: Ensure advocacy issues are addressed in all aspects of research with patient participants. The Core will ensure that all SPORE components properly incorporate advocacy issues or concerns. We will accomplish this in two ways including patient advocacy and patient feedback. Aim 6: Assist investigators in preparing scholarly presentations, publications, regulatory documents, and all other SPORE-related products. This core will be responsible for completing documentation required for investigators presenting at local and national meetings and submitting of documents to institutional regulatory bodies (e.g., human and animal studies protocols), publications, and final peer-reviewed manuscripts supported by SPORE funds to PubMed Central immediately upon acceptance.