Informing synthetic decision making using cheminformatic and bioinformatic profil

使用化学信息学和生物信息学分析为综合决策提供信息

• 批准号: 7696771
• 负责人: PAUL ANDREW CLEMONS
• 金额: $ 22.42万
• 依托单位: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-30 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7696771
• 关键词: Area; Biodiversity; Bioinformatics; Biological; Biological Assay; Biological Testing; Biology; Cells; Chemical Structure; Chemicals; Collection; Communities; Computer Analysis; Constitution; Coupling; Data; Data Analyses; Data Set; Decision Making; Descriptor; Disease; Elements; Ensure; Enzyme Inhibition; Feedback; Gene Expression; Heart; Image; Learning; Libraries; Measurement; Measures; Methods; Modeling; Molecular; Numbers; Organic Chemistry; Outcome; Outcome Measure; Pathway interactions; Performance; Property; Research; S Phase; Screening procedure; Shapes; Skeletal system; Speed; Structure; Structure-Activity Relationship; Synthesis Chemistry; base; cheminformatics; drug discovery; method development; molecular shape; research study; size; small molecule; stereochemistry; tool

Extend a chemical biology information model currently used to analyze small-molecule screening data to the area of synthetic organic chemistry, so that decisions in synthesis can be guided by empirical data obtained from the small molecules synthesized in Projects 1, 2, among others. (Project 4)

将目前用于分析小分子筛选数据的化学生物学信息模型扩展为 合成有机化学领域，以便通过经验数据来指导合成决策 从项目1、2等合成的小分子中获得。(项目4)