Core--Histochemistry

组织化学核心提供最先进的技术支持、设施，以及本计划项目主要研究人员所需的组织化学和形态方法的协作专业知识。组织化学核心服务和设施包括组织固定和处理(包括冷冻切片)、组织学和组织化学染色(例如LacZ)、免疫细胞化学、荧光显微镜、图像分析和激光捕获 显微解剖。如有必要，组织化学核心可提供原位杂交和共聚焦显微镜。被提议的组织化学核心主任是丹尼斯·G·巴斯金博士，他是组织化学和糖尿病/内分泌学研究领域的知名科学家。他是华盛顿大学的医学研究教授，也是西雅图退伍军人医学中心的高级研究职业科学家。巴斯金博士将监督组织化学核心的行政和科学活动，并担任利用该核心的项目项目研究的合作者。

The Histochemistry Core provides state-of-the-art technical support, facilities, and collaborative expertise for histochemical and morphological methods needed by the principal investigators of this Program Project. Histochemistry Core services and facilities include tissue fixation and processing (including cryostat sectioning), histological and histochemical staining (e.g., lacZ), immunocytochemistry, fluorescence microscopy, image analysis, and laser capture microdissection. If necessary, the Histochemistry Core can provide in situ hybridization and confocal microscopy. The proposed Director of the Histochemistry Core is Dr. Denis G. Baskin, an established scientist in the fields of histochemistry and diabetes/endocrinology research. He is Research Professor of Medicine at the University of Washington and is also Senior Research Career Scientist in the Seattle VA Medical Center. Dr. Baskin will oversee the administrative and scientific activities of the Histochemistry Core and act as a collaborator on Program Project studies that utilize the core.