Administrative Core

项目概要/摘要-核心A HCC OvCa SPORE管理核心（核心A）由SPORE PI罗纳德巴克诺维奇（医学博士）共同指导， 博士和Robert Edwards，MD。核心A将（i）提供科学、财政和一般行政监督， 所有的孢子组成部分，（ii）工作，以促进三个孢子项目的研究生产力，（iii） 扩展SPORE的两个共享资源核心的效用和效率，以及（iv）确保 职业提升计划（CEP）和发展研究计划（DRP），以产生一个管道 新的OvCa调查员和项目。为了确保SPORE的成功，核心A将协调共享 SPORE数据以及内部和外部通信和交互。这包括协调 与合作机构达成协议，并与患者倡导者进行社区外联。核心A将召开 所有SPORE研究者参加的月度会议，协调定期行政和科学 审查、发布和公布RFA，并安排审查收到的CEP和DRP申请，以及 与NCI转化研究计划办公室密切合作。它将提供行政框架， SPORE执行委员会、内部顾问委员会（IAB）和外部顾问委员会通过该委员会 (EAB)可以评估项目活动，并将适当地重新分配资源，以最大限度地实现 的翻译目标。核心A将监控各个SPORE、CEP和DRP的预算 项目和核心，以确保在SPORE和机构共享之间不会发生重复工作 资源，国家财团或合作团体，或其他资助的研究赠款。核心也将 确保SPORE的研究活动符合所有地方和联邦法规 和准则，包括保护病人安全和个人健康信息的准则。核心A将 受益于合格的SPORE管理员的工作，该管理员协助安排和准备报告 和手稿。 影响：通过核心A功能，整个SPORE将受益于基本的 服务，每个SPORE组件将有机会最大限度地致力于 研究和以患者为导向的进展卵巢癌。

PROJECT SUMMARY/ABSTRACT – CORE A The HCC OvCa SPORE Administrative Core (Core A) is co-directed by SPORE PIs Ronald Buckanovich, MD, PhD and Robert Edwards, MD. Core A will (i) provide scientific, fiscal, and general administrative oversight to all SPORE components, (ii) work to facilitate the research productivity of the three SPORE Projects, (iii) expand the utility and efficiency of the SPORE’s two Shared Resource Cores, and (iv) ensure the success of the Career Enhancement Program (CEP) and Developmental Research Program (DRP) to generate a pipeline of new OvCa investigators and projects. To ensure the success of the SPORE, Core A will coordinate sharing of SPORE data as well as internal and external communications and interactions. This includes coordinating agreements with collaborating institutions and community outreach with patient advocates. Core A will convene monthly meetings attended by all SPORE Investigators, coordinate periodic administrative and scientific reviews, release and publicize RFAs and arrange for the review of received CEP and DRP applications, and work closely with the NCI Translational Research Program Office. It will provide the administrative framework through which the SPORE Executive Committee, Internal Advisory Board (IAB), and External Advisory Board (EAB) can evaluate program activities and will redirect resources, as appropriate, to maximize progress toward the SPORE’s translational goals. Core A will monitor the budgets of the individual SPORE, CEP, and DRP Projects and Cores to ensure that no duplication of effort occurs between the SPORE and institutional shared resources, national consortia or cooperative groups, or other funded research grants. The Core will also ensure that the SPORE’s research activities are conducted in compliance with all local and federal regulations and guidelines, including those for protecting the safety and personal health information of patients. Core A will benefit from the effort of a qualified SPORE Administrator who assists in scheduling and in preparing reports and manuscripts. Impact: Through Core A functions, the SPORE as a whole will benefit from the centralization of essential services, and each SPORE component will be afforded the opportunity to maximize the effort devoted to research and patient-oriented advances in ovarian cancer.