Community-Driven Indigenous Research, Cultural Strengths & Leadership to Advance Equity in Drug Use Outcomes (CIRCLE)

项目摘要 药物和酒精使用相关的健康问题和过量死亡不成比例地影响质量和 许多美国印第安人和阿拉斯加原住民（土著）社区的寿命。拟议 社区驱动的土著研究，文化优势和领导力，以促进物质使用的公平 成果（圈）卓越中心（P50）旨在解决与药物使用有关的健康问题， 与不同的原住民社区合作。通过研究、培训和推广，我们将应对 土著人民呼吁更加注重恢复和预防、力量来源、文化和 以家庭为基础的健康方法和政策解决方案。P50项目和核心将与 强调四个交叉领域，所有这些领域都以促进土著健康公平为基础：1） 土著和同盟领导; 2）社区/部落为基础的竞争性研究（C/TBPR）; 3）解决 通过精确的公共卫生异源性;和4）集中优势，包括评估土著文化 健康的框架。为了反映这些专题方法，中心的总体目标包括： 以影响为重点的C/TBPR，以确定物质使用风险和保护因素以及干预措施的异质性 方面的影响.我们还将促进土著学者的发展，以扩大土著的自主权， 以及围绕酒精和药物使用的研究、实践和政策的创新。我们的目标是进一步扩大和 深化我们与教育设施，研究人员，部落和城市原住民社区，政策， 制造商和公众作为国家资源，更快地吸收和分享新方法， 促进土著人健康公平的措施和方案。为了实现这些目标，该中心将 1）行政核心，负责监督治理、行政结构、科学优先事项，以及 2）研究核心，提供方法学方面的专门知识，以支持中心的研究; 3)支持土著药物使用研究创新的核心试点项目，以及4）三个研究项目， 将开展多学科和协同科学，重点是吸毒预防，干预和政策。 拟议的工作符合NIDA的种族平等倡议行动步骤，包括增加CBPR和公平- 推动伙伴关系，以消除药物使用不公平现象。

PROJECT SUMMARY Drug and alcohol use related health problems and overdose deaths disproportionately impact quality and longevity of life for many American Indian and Alaska Native (Indigenous) communities. The proposed Community-Driven Indigenous Research, Cultural Strengths & Leadership to Advance Equity in Substance Use Outcomes (CIRCLE) Center of Excellence (P50) aims to address drug use related health problems in collaboration with diverse Indigenous communities. Through research, training, and outreach, we will respond to calls from Indigenous Peoples for enhanced focus on recovery and prevention, sources of strength, culture and family-based approaches to wellness, and policy solutions. The P50 projects and cores will operate with emphasis on four cross-cutting domains, all centered on a bedrock of promoting Indigenous Health Equity: 1) Indigenous & Allied Leadership; 2) Community/Tribally Based Participatory Research (C/TBPR); 3) Addressing Heterogeneity via Precision Public Health; and 4) Centering Strengths, including Assessing Indigenous Cultural Frameworks of Health. Reflecting these thematic approaches, the Center's overarching aims include conducting impact-focused, C/TBPR to identify heterogeneity in substance use risk and protective factors and intervention effects. We will also foster the development of Indigenous scholars to expand Indigenous autonomy, capacity and innovation in research, practice, and policy surrounding alcohol and drug use. We further aim to expand and deepen our engagement with educational facilities, researchers, Tribal and Urban Native communities, policy makers, and the public to serve as a national resource for more rapid uptake and sharing of novel methods, measures, and programs in service to Indigenous health equity. To achieve these goals, the Center will house the following: 1) Administrative Core to oversee governance, administrative structures, scientific priorities, and training activities; 2) Research Core to provide methodological expertise to support the research of the Center; 3) Pilot Project Core to support innovation in Indigenous drug use research, and 4) Three Research Projects that will conduct multidisciplinary and synergistic science focused on drug use prevention, intervention, and policy. The proposed work aligns with NIDA's Racial Equity Initiative action steps, including increased CBPR and equity- driven partnerships to combat drug use inequities.