Development of a Novel Virtual Reality Treatment for Emerging Adults with ADHD

开发一种针对患有多动症的新兴成人的新型虚拟现实治疗方法

• 批准号: 10721084
• 负责人: Joshua Morris Langberg
• 金额: $ 59.92万
• 依托单位: RUTGERS, THE STATE UNIV OF N.J.
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10721084
• 关键词: Address; Adherence; Adult; Algorithms; Attention; Attention deficit hyperactivity disorder; Behavior; Behavior Therapy; Behavioral; Behavioral Mechanisms; Clinical Psychology; Computer software; Data; Development; Disease; Dose; Engineering; Engineering Psychology; Environment; Evaluation; Executive Dysfunction; Eye; Feedback; Focus Groups; Goals; Impairment; Individual; Interruption; Intervention; Libraries; Light; Measures; Mediation; Mediator; Mental Health; Monitor; Motivation; Mus; Parents; Participant; Performance; Pharmaceutical Preparations; Phase; Practice Guidelines; Productivity; Protocols documentation; Psychological reinforcement; Randomized; Randomized, Controlled Trials; Reading; Recommendation; Research Personnel; Resolution; Resources; Rewards; Structure; Students; Surveys; Symptoms; Techniques; Technology; Testing; Time; Traction; Treatment Efficacy; Universities; Visual; Work; Writing; cognitive training; college; computer science; contingency management; distraction; efficacy evaluation; emerging adult; evidence base; experience; follow-up; gaze; health equity; improved; invention; laptop; novel; pilot test; professional atmosphere; randomized trial; support tools; teacher; tool; university student; usability; virtual reality; virtual reality environment; virtual reality headset; virtual reality intervention; virtual world; ward

Project Summary/Abstract Attention deficit hyperactivity disorder (ADHD) is a highly prevalent and impairing disorder. Behavioral treatments that structure the environment and provide frequent and consistent monitoring are efficacious but resource and time intensive, leading to problems with access and adherence. This study will utilize a virtual reality platform to minimize distractions and provide the structure and monitoring necessary for individuals with ADHD to maintain focus while completing homework and studying. The virtual reality (VR) headset will place students in a distraction free environment that automates the frequent and consistent point-of-performance feedback and reinforcement that serves as the core mechanisms of behavioral treatment. The VR technology will allow for direct comparison between two novel intervention approaches and a VR passthrough to laptop control. Survey and objective data (keyboard and mouse click data) will be collected to directly evaluate the impact of VR on core targets of action, including concentration, motivation, and homework effort. This novel alternative to medication and behavior therapy offers a completely new tool for supporting individuals with ADHD. This study includes four separate projects, three in the R61 phase and a large randomized trial in the R33 phase. Project 1 (N = 30 college students with ADHD) focuses on optimizing and refining objective data capture algorithms to quantify on-task behavior and work productivity while completing a variety of different types of academic tasks. Project 2 (N = 30 college students with ADHD) focuses on developing and refining on-task monitoring and performance feedback algorithms within VR, including a green, yellow, and red-light display that allows individuals with ADHD to receive consistent and frequent feedback and work towards specific short-terms goals and rewards. Focus groups will also be completed to improve VR feasibility and usability. Project 3 involves a small randomized controlled trial to ensure that the key targets of action are engaged. Project 3 will assess the feasibility/usability and preliminary effects of the VR environment alone (n=15) as compared to VR environment + contingency management (n=15) and a passthrough control wearing of the VR headset (n=15). Time on-task, homework motivation, and homework effort are the proposed mechanisms of action. If the Go/No-Go criteria are met in Project 3, the protocol moves to Project 4, which involves a randomized trial of the VR intervention. 252 college students with ADHD will be randomized to receive either: (1) VR environment alone, (2) VR environment + contingency management, or (3) pass-through VR headset control for 8 weeks. Measures of mental health and academic functioning will be collected at baseline, 4 weeks, 8 weeks, and at a 3-month follow-up.

项目总结/摘要 注意力缺陷多动障碍（ADHD）是一种高度流行的损害性疾病。行为 结构化环境并提供频繁和一致的监测的治疗是有效的， 资源和时间密集型，导致访问和遵守方面的问题。本研究将利用虚拟 现实平台，以尽量减少分心，并提供必要的结构和监测个人与 ADHD在完成作业和学习时保持专注。虚拟现实（VR）头显将 学生在一个分心自由的环境，自动化的频繁和一致的性能点 反馈和强化是行为治疗的核心机制。vr技术 将允许直接比较两种新的干预方法和VR直通到笔记本电脑 控制将收集调查和客观数据（键盘和鼠标点击数据），以直接评估 VR对核心行动目标的影响，包括专注力，动机和家庭作业的努力。这本小说 替代药物和行为治疗提供了一个全新的工具，支持个人与 多动症。这项研究包括四个独立的项目，三个在R61阶段，一个大型的随机试验， R33阶段。项目1（N = 30名患有ADHD的大学生）专注于优化和精炼客观数据 捕获算法，以量化任务行为和工作效率，同时完成各种不同的 学术任务的类型。项目2（N = 30名患有ADHD的大学生）专注于开发和完善 VR中的任务监控和性能反馈算法，包括绿色、黄色和红色指示灯 显示器，允许患有ADHD的个人接收一致和频繁的反馈，并努力 短期目标和奖励。还将完成焦点小组讨论，以提高VR的可行性， 可用性项目3涉及一项小型随机对照试验，以确保行动的关键目标是 订婚了项目3将单独评估VR环境的可行性/可用性和初步效果 （n=15）与VR环境+应急管理（n=15）和穿通对照佩戴相比 VR头戴式耳机（n=15）。作业时间、作业动机和作业努力度是本研究的三个重要指标 行动机制。如果在项目3中满足Go/No-Go标准，则方案移至项目4， 涉及虚拟现实干预的随机试验。252名患有ADHD的大学生将被随机分配到 接收：（1）单独的VR环境，（2）VR环境+应急管理，或（3）直通 VR头显控制8周。心理健康和学术功能的措施将收集在 基线、4周、8周和3个月随访时。