EMERGEncy ID Net Study

描述(由申请人提供)：急诊ID网络计划是由美国11个不同地理位置的大学附属医院急诊科组成的哨兵网络。该项目自1995年以来一直由疾病控制中心(CDC)资助，旨在通过评估疾病流行率、风险因素以及在向急诊科提交报告的不同人群中对社区急性演示的管理实践，来应对新出现的传染病的威胁。急诊ID Net前瞻性地进行了几项调查，最近的研究内容包括：急性肾盂肾炎患者中的尿路病原菌耐药性和转归；对感染的特定宿主基因反应；急诊医生(EP)对天花疫苗接种的态度和对生物恐怖威胁的感知风险；以及皮肤和软组织感染患者中耐甲氧西林金黄色葡萄球菌(MRSA)的流行情况。紧急身份证网计划的具体目标是继续与疾控中心合作，对美国各种新出现的感染进行持续调查。这将通过以下方式实现：1)识别急诊科患者中新出现的感染；2)制定研究目标和材料；3)获得人类受试者保护委员会进行研究所需的批准；4)通过急诊科患者的登记和跟踪来实施研究；5)管理收集的数据；6)产生研究结果，并在同行评议的出版物和科学会议上报告我们的发现。紧急身份证网方案在过去10年中取得的成就表明，它有能力迅速解决各种紧急的公共卫生传染病问题，并将调查结果有效地传播给传染病、公共卫生和紧急医学从业者以及公众。

DESCRIPTION (provided by applicant): The EMERGEncy ID NET program is a sentinel network of 11 geographically-diverse, university-affiliated hospital emergency departments in the United States. This program, which has been funded by the Centers for Disease Control (CDC) since 1995, was established to address the threat of emerging infectious diseases by assessing disease prevalence, risk factors, and management practices for acute presentations from the community among a diverse population presenting to emergency departments. EMERGEncy ID NET has prospectively conducted several investigations, most recently addressing uropathogen antimicrobial resistance and outcomes among patients with acute pyelonephritis; specific host gene responses to infections; emergency physicians' (EPs) attitudes towards smallpox vaccination and perceived risk of a bioterrorist threat; and the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) among patients with skin and soft tissue infections. The specific aim for the EMERGEncy ID NET program is to continue collaboration with the CDC to conduct ongoing investigations of various emerging infections in the United States. This will be accomplished by: 1) identifying emerging infections among emergency department patients; 2) developing study objectives and materials; 3) obtaining necessary approvals to conduct the research from Human Subject Protection Committees; 4) implementing the studies through enrollment and follow-up of emergency department patients; 5) managing data collected; 6) generating results from studies and reporting our findings in peer-reviewed publications and at scientific conferences. The accomplishments of the EMERGEncy ID NET program over the past 10 years demonstrate its capability to rapidly address a variety of urgent public health infectious disease problems and propagate the results of investigations effectively to infectious diseases, public health, and emergency medicine Practitioners, and to the public.