American College of Radiology Imaging Network
美国放射学院影像网络
基本信息
- 批准号:7627986
- 负责人:
- 金额:$ 889.64万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:1999
- 资助国家:美国
- 起止时间:1999-03-06 至 2012-12-31
- 项目状态:已结题
- 来源:
- 关键词:American College of Radiology Imaging NetworkAnatomyBiological MarkersBiometryCancer DetectionClinicalClinical TrialsCommunitiesDetectionDevelopmentDiagnosisEffectivenessGeneticGrantImageInstitutionInterventionLeadershipMalignant NeoplasmsMeasuresMethodsMolecular BiologyMonitorPathway interactionsPatientsPhysiciansPhysiologyPlayPopulations at RiskPreventionPreventive InterventionResearchResearch PersonnelRoleSpecialistTechniquesTechnologyUniversitiesWorkanticancer researchbasebioimagingcancer carecancer imagingcancer therapyimprovedprognosticresponsetumor
项目摘要
A growing understanding of the multiple genetic and environmental pathways that contribute to the
development of cancer is leading to the concept of a personalized approach to cancer therapy and
prevention. This requires techniques to characterize patient and tumor factors that will drive specific
targeted interventions and measure their effectiveness. Biomedical imaging now offers the opportunity to
characterize tumor anatomy, physiology, and molecular biology in unprecedented ways. The challenge is to
harness this technology to develop quantitative approaches to diagnosis that will support the development
and application of targeted treatments and preventive interventions. Since its inception, ACRIN has
developed and implemented multicenter clinical trials to establish the effectiveness of imaging in the
detection, characterization and monitoring of cancer. Working with its biostatistics center at Brown
University, ACRIN has assembled a unique organization of hundreds of clinical imaging specialists, other
clinicians, and non-physician researchers at more than a hundred institutions nationally and internationally
working collaboratively with the broader cancer research community dedicated to cancer imaging research.
Over the next grant cycle, ACRIN proposes 3 major scientific objective related to the theme of personalized
cancer care: 1. targeted surveillance of at-risk populations; 2.characterization of cancer in order to drive
targeted therapy; and 3. development of imaging-based predictive and prognostic biomarkers of response to
targeted treatment. Through its continued leadership in the imaging community, ACRIN will play a pivotal
role in the advancement of cancer detection and therapy.
ACRIN will work to discover ways for imaging to improve cancer care. This includes determining the optimal
methods to detect cancer early in order to provide the best opportunity for cure, and establishing techniques
to characterize cancer and its response to treatment in order to choose the most appropriate therapy.
对多种遗传和环境途径的理解日益加深
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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MITCHELL D. SCHNALL其他文献
MITCHELL D. SCHNALL的其他文献
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{{ truncateString('MITCHELL D. SCHNALL', 18)}}的其他基金
ECOG-ACRIN-Based QIN Resource for Advancing Quantitative Cancer Imaging in Clinical Trials
基于 ECOG-ACRIN 的 QIN 资源,用于推进临床试验中的定量癌症成像
- 批准号:
8802078 - 财政年份:2015
- 资助金额:
$ 889.64万 - 项目类别:
ECOG-ACRIN-Based QIN Resource for Advancing Quantitative Cancer Imaging in Clinical Trials
基于 ECOG-ACRIN 的 QIN 资源,用于推进临床试验中的定量癌症成像
- 批准号:
9038339 - 财政年份:2015
- 资助金额:
$ 889.64万 - 项目类别:
RADIAL DCE-MRI FOR ASSESSMENT OF TUMOR VASCULAR RESPONSE
用于评估肿瘤血管反应的径向 DCE-MRI
- 批准号:
8169041 - 财政年份:2010
- 资助金额:
$ 889.64万 - 项目类别:
IMPROVED ANALYTIC MODELS FOR ANALYSIS OF DCE-MRI DATA SETS
用于 DCE-MRI 数据集分析的改进分析模型
- 批准号:
8169042 - 财政年份:2010
- 资助金额:
$ 889.64万 - 项目类别:
RADIAL DCE-MRI FOR ASSESSMENT OF TUMOR VASCULAR RESPONSE
用于评估肿瘤血管反应的径向 DCE-MRI
- 批准号:
7955315 - 财政年份:2009
- 资助金额:
$ 889.64万 - 项目类别:
IMPROVED ANALYTIC MODELS FOR ANALYSIS OF DCE-MRI DATA SETS
用于 DCE-MRI 数据集分析的改进分析模型
- 批准号:
7955316 - 财政年份:2009
- 资助金额:
$ 889.64万 - 项目类别:
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